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Abnormal basophil count

MedGen UID:
663422
•Concept ID:
C0580547
•
Finding
Synonyms: Basophil count abnormal; Basophil count outside reference range
SNOMED CT: Basophil count abnormal (165528007); Basophil count outside reference range (165528007)
 
HPO: HP:0031806

Definition

Any deviation from the normal number of basophils per volume in the blood circulation. [from HPO]

Professional guidelines

PubMed

Blood Cell Count Ratios at Baseline are Associated with Initial Clinical Response to Clozapine in Treatment-Resistant, Clozapine-Naïve, Schizophrenia-Spectrum Disorder.
Llorca-Bofí V, Bioque M, Madero S, Mallorquí A, Oliveira C, Garriga M, Parellada E, García-Rizo C
Pharmacopsychiatry 2024 Jul;57(4):173-179. Epub 2024 Apr 15 doi: 10.1055/a-2290-6386. PMID: 38621701
Evaluation of the Beckman Coulter UniCel DxH 800 and Abbott Diagnostics Cell-Dyn Sapphire hematology analyzers on pediatric and neonatal specimens in a tertiary care hospital.
Tan BT, Nava AJ, George TI
Am J Clin Pathol 2011 Jun;135(6):929-38. doi: 10.1309/AJCP2EXNSLGGRVSQ. PMID: 21571966
Proposal of a morphologic bone marrow response score for imatinib mesylate treatment in chronic myelogenous leukemia.
Lugli A, Ebnoether M, Cogliatti SB, Gratwohl A, Passweg J, Hess U, Korte W, Hawle H, Tinguely M, Borisch B, Mach-Pascual S, Von Juergensonn S, Tichelli A, Dirnhofer S
Hum Pathol 2005 Jan;36(1):91-100. doi: 10.1016/j.humpath.2004.10.012. PMID: 15712187

Recent clinical studies

Therapy

A lasso and random forest model using flow cytometry data identifies primary myelofibrosis.
Zhang F, Wang YZ, Chang Y, Yuan XY, Shi WH, Shi HX, Shen JZ, Liu YR
Cytometry B Clin Cytom 2024 Jul;106(4):272-281. Epub 2024 Apr 22 doi: 10.1002/cyto.b.22173. PMID: 38647185
An immune window of opportunity to prevent spontaneous abortion: prepregnancy peripheral leukocytes and subsets were associated with a decreased risk of spontaneous abortion.
Liu Y, Yang Y, Zhao C, Liu M, Xu D, Wu H, Lei J, Deng Y, Xie W, Huang J, Wu S, Zhang Y, Zhang H, He Y, Peng Z, Wang Y, Shen H, Wang Q, Zhang Y, Yan D, Wang L, Ma X
Hum Reprod 2024 Feb 1;39(2):326-334. doi: 10.1093/humrep/dead261. PMID: 38166353
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities.
Steen NE, Rahman Z, Szabo A, Hindley GFL, Parker N, Cheng W, Lin A, O'Connell KS, Sheikh MA, Shadrin A, Bahrami S, Karthikeyan S, Hoseth EZ, Dale AM, Aukrust P, Smeland OB, Ueland T, Frei O, Djurovic S, Andreassen OA
Schizophr Bull 2023 Sep 7;49(5):1345-1354. doi: 10.1093/schbul/sbad082. PMID: 37319439Free PMC Article
Prognostic factors in chronic myeloid leukaemia.
Hernández-Boluda JC, Cervantes F
Best Pract Res Clin Haematol 2009 Sep;22(3):343-53. doi: 10.1016/j.beha.2009.04.005. PMID: 19959085
Syndromes of acute nonlymphocytic leukemia.
Koeffler HP
Ann Intern Med 1987 Nov;107(5):748-58. doi: 10.7326/0003-4819-107-5-748. PMID: 3310797

Prognosis

Elucidating hematological profile and electrolyte balance in oral cancer patients.
Sundaravadivelu I, Renu K, Kavitha S, Priya VV, Gayathri R, Ronsivalle V, Cicciù M, Minervini G
Minerva Dent Oral Sci 2024 Aug;73(4):224-229. Epub 2024 Jul 2 doi: 10.23736/S2724-6329.24.04902-7. PMID: 38953794
Characterization and trajectories of hematological parameters prior to severe COVID-19 based on a large-scale prospective health checkup cohort in western China: a longitudinal study of 13-year follow-up.
Lin Y, Yang Y, Xiang N, Wang L, Zheng T, Zhuo X, Shi R, Su X, Liu Y, Liao G, Du L, Huang J
BMC Med 2024 Mar 7;22(1):105. doi: 10.1186/s12916-024-03326-x. PMID: 38454462Free PMC Article
Low serum neutrophil count predicts a positive prostate biopsy.
Fujita K, Imamura R, Tanigawa G, Nakagawa M, Hayashi T, Kishimoto N, Hosomi M, Yamaguchi S
Prostate Cancer Prostatic Dis 2012 Dec;15(4):386-90. Epub 2012 Jul 10 doi: 10.1038/pcan.2012.27. PMID: 22777394
Prognostic factors in chronic myeloid leukaemia.
Hernández-Boluda JC, Cervantes F
Best Pract Res Clin Haematol 2009 Sep;22(3):343-53. doi: 10.1016/j.beha.2009.04.005. PMID: 19959085
Prevalence and clinical characteristics of myelodysplastic syndrome with bone marrow eosinophilia or basophilia.
Matsushima T, Handa H, Yokohama A, Nagasaki J, Koiso H, Kin Y, Tanaka Y, Sakura T, Tsukamoto N, Karasawa M, Itoh K, Hirabayashi H, Sawamura M, Shinonome S, Shimano S, Miyawaki S, Nojima Y, Murakami H
Blood 2003 May 1;101(9):3386-90. Epub 2002 Dec 27 doi: 10.1182/blood-2002-03-0947. PMID: 12506028

Clinical prediction guides

Characterization and trajectories of hematological parameters prior to severe COVID-19 based on a large-scale prospective health checkup cohort in western China: a longitudinal study of 13-year follow-up.
Lin Y, Yang Y, Xiang N, Wang L, Zheng T, Zhuo X, Shi R, Su X, Liu Y, Liao G, Du L, Huang J
BMC Med 2024 Mar 7;22(1):105. doi: 10.1186/s12916-024-03326-x. PMID: 38454462Free PMC Article
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities.
Steen NE, Rahman Z, Szabo A, Hindley GFL, Parker N, Cheng W, Lin A, O'Connell KS, Sheikh MA, Shadrin A, Bahrami S, Karthikeyan S, Hoseth EZ, Dale AM, Aukrust P, Smeland OB, Ueland T, Frei O, Djurovic S, Andreassen OA
Schizophr Bull 2023 Sep 7;49(5):1345-1354. doi: 10.1093/schbul/sbad082. PMID: 37319439Free PMC Article
Effects of Different Kinds of Hand Sanitizers on Complete Blood Count and Leukocyte Differential Count.
Li Z, Yang S, Yang B, Ding J, Cui L
Clin Lab 2022 Aug 1;68(8) doi: 10.7754/Clin.Lab.2021.211005. PMID: 35975494
Epidemiological and clinical implications of asymptomatic malaria and schistosomiasis co-infections in a rural community in western Kenya.
Kamau E, Yates A, Maisiba R, Singoei V, Opot B, Adeny R, Arima CO, Otieno V, Sumbi CS, Okoth RO, Abdi F, Mwalo M, Ochola J, Otieno J, Ake J, Imbach M, Turley HA, Juma D, Akala HM, Owuoth J, Andagalu B, Crowell TA, Nwoga C, Cowden J, Polyak CS; RV393 Study Group
BMC Infect Dis 2021 Sep 9;21(1):937. doi: 10.1186/s12879-021-06626-2. PMID: 34503469Free PMC Article
Acute erythroid neoplastic proliferations. A biological study based on 62 patients.
Domingo-Claros A, Larriba I, Rozman M, Irriguible D, Vallespí T, Aventin A, Ayats R, Millá F, Solé F, Florensa L, Gallart M, Tuset E, Lopez C, Woessner S
Haematologica 2002 Feb;87(2):148-53. PMID: 11836165

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