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Gnathomiasis

MedGen UID:
6651
Concept ID:
C0018013
Disease or Syndrome
Synonym: Infection by Gnathostoma
SNOMED CT: Infection caused by Gnathostoma (44086001); Infection by Gnathostoma (44086001); Gnathostomiasis (44086001); Gnathomiasis (44086001); Gnathostomosis (44086001)
 
Monarch Initiative: MONDO:0005776

Definition

An infection that is caused by nematodes of the genus Gnathostoma, which is commonly found in Southeast Asia, and which is transmitted via the consumption of contaminated raw/undercooked birds, eels, fish, frogs, or reptiles. The pattern of symptoms is species-dependent, and extraintestinal manifestations are due to larval migration (e.g., pulmonary infiltrates, eosinophilic meningitis, or painful, pruritic subcutaneous swellings, and peripheral blood eosinophilia). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGnathomiasis

Professional guidelines

PubMed

Senthong V, Chindaprasirt J, Sawanyawisuth K
Hawaii J Med Public Health 2013 Jun;72(6 Suppl 2):52-4. PMID: 23901385Free PMC Article
Strady C, Dekumyoy P, Clement-Rigolet M, Danis M, Bricaire F, Caumes E
Am J Trop Med Hyg 2009 Jan;80(1):33-5. PMID: 19141836
Ittiprasert W, Butraporn P, Kitikoon V, Klongkamnuankarn K, Pholsena K, Vanisaveth V, Sakolvaree Y, Chongsa-nguan M, Tapchaisri P, Mahakunkijcharoen Y, Kurazono H, Hayashi H, Chaicumpa W
Parasitol Int 2000 Sep;49(3):209-18. doi: 10.1016/s1383-5769(00)00046-5. PMID: 11426576

Recent clinical studies

Etiology

Lupi O, Downing C, Lee M, Pino L, Bravo F, Giglio P, Sethi A, Klaus S, Sangueza OP, Fuller C, Mendoza N, Ladizinski B, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):929-44; quiz 945-6. doi: 10.1016/j.jaad.2014.11.034. PMID: 26568337
Sawanyawisuth K, Chotmongkol V
Handb Clin Neurol 2013;114:207-15. doi: 10.1016/B978-0-444-53490-3.00015-7. PMID: 23829911
Pittella JE
Handb Clin Neurol 2013;114:65-88. doi: 10.1016/B978-0-444-53490-3.00005-4. PMID: 23829901
Herman JS, Chiodini PL
Clin Microbiol Rev 2009 Jul;22(3):484-92. doi: 10.1128/CMR.00003-09. PMID: 19597010Free PMC Article
Nithiuthai S, Anantaphruti MT, Waikagul J, Gajadhar A
Vet Parasitol 2004 Dec 9;126(1-2):167-93. doi: 10.1016/j.vetpar.2004.09.018. PMID: 15567584

Diagnosis

Smith S, Wilson I, Starck L, Binotto E, Ho J, Hanson J
Med J Aust 2021 Aug 16;215(4):164-165.e1. Epub 2021 Jul 22 doi: 10.5694/mja2.51189. PMID: 34296434
Liu GH, Sun MM, Elsheikha HM, Fu YT, Sugiyama H, Ando K, Sohn WM, Zhu XQ, Yao C
Parasit Vectors 2020 Dec 9;13(1):616. doi: 10.1186/s13071-020-04494-4. PMID: 33298141Free PMC Article
Lupi O, Downing C, Lee M, Pino L, Bravo F, Giglio P, Sethi A, Klaus S, Sangueza OP, Fuller C, Mendoza N, Ladizinski B, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):929-44; quiz 945-6. doi: 10.1016/j.jaad.2014.11.034. PMID: 26568337
Román GC
Handb Clin Neurol 2014;121:1521-48. doi: 10.1016/B978-0-7020-4088-7.00102-4. PMID: 24365434
Sawanyawisuth K, Chotmongkol V
Handb Clin Neurol 2013;114:207-15. doi: 10.1016/B978-0-444-53490-3.00015-7. PMID: 23829911

Therapy

Smith S, Wilson I, Starck L, Binotto E, Ho J, Hanson J
Med J Aust 2021 Aug 16;215(4):164-165.e1. Epub 2021 Jul 22 doi: 10.5694/mja2.51189. PMID: 34296434
Chai JY, Jung BK, Hong SJ
Korean J Parasitol 2021 Jun;59(3):189-225. Epub 2021 Jun 21 doi: 10.3347/kjp.2021.59.3.189. PMID: 34218593Free PMC Article
Lupi O, Downing C, Lee M, Pino L, Bravo F, Giglio P, Sethi A, Klaus S, Sangueza OP, Fuller C, Mendoza N, Ladizinski B, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):929-44; quiz 945-6. doi: 10.1016/j.jaad.2014.11.034. PMID: 26568337
Herman JS, Chiodini PL
Clin Microbiol Rev 2009 Jul;22(3):484-92. doi: 10.1128/CMR.00003-09. PMID: 19597010Free PMC Article
Magaña M, Messina M, Bustamante F, Cazarín J
Am J Dermatopathol 2004 Apr;26(2):91-5. doi: 10.1097/00000372-200404000-00001. PMID: 15024188

Prognosis

Bravo FG
Mod Pathol 2020 Jan;33(Suppl 1):118-127. Epub 2019 Nov 4 doi: 10.1038/s41379-019-0399-1. PMID: 31685961
Lupi O, Downing C, Lee M, Bravo F, Giglio P, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):947-57; quiz 957-8. doi: 10.1016/j.jaad.2014.11.035. PMID: 26568338
Lupi O, Downing C, Lee M, Pino L, Bravo F, Giglio P, Sethi A, Klaus S, Sangueza OP, Fuller C, Mendoza N, Ladizinski B, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):929-44; quiz 945-6. doi: 10.1016/j.jaad.2014.11.034. PMID: 26568337
Lv S, Zhang Y, Steinmann P, Zhou XN, Utzinger J
Adv Parasitol 2010;72:351-408. doi: 10.1016/S0065-308X(10)72012-1. PMID: 20624537
Bravo F, Sanchez MR
Dermatol Clin 2003 Oct;21(4):655-68, viii. doi: 10.1016/s0733-8635(03)00090-1. PMID: 14717406

Clinical prediction guides

Kongwattananon W, Wiriyabanditkul T, Supwatjariyakul W, Somkijrungroj T
Ocul Immunol Inflamm 2023 Jul;31(5):1092-1096. Epub 2022 May 19 doi: 10.1080/09273948.2022.2073239. PMID: 35588303
Sears WJ, Qvarnstrom Y, Dahlstrom E, Snook K, Kaluna L, Baláž V, Feckova B, Šlapeta J, Modry D, Jarvi S, Nutman TB
Clin Infect Dis 2021 Oct 5;73(7):e1594-e1600. doi: 10.1093/cid/ciaa1791. PMID: 33252651Free PMC Article
Bravo FG
Mod Pathol 2020 Jan;33(Suppl 1):118-127. Epub 2019 Nov 4 doi: 10.1038/s41379-019-0399-1. PMID: 31685961
Intapan PM, Khotsri P, Kanpittaya J, Chotmongkol V, Sawanyawisuth K, Maleewong W
Am J Trop Med Hyg 2010 Oct;83(4):927-9. doi: 10.4269/ajtmh.2010.10-0113. PMID: 20889894Free PMC Article
Eduardo SL
Southeast Asian J Trop Med Public Health 1991 Dec;22 Suppl:16-22. PMID: 1822878

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