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Dermatomyofibroma

MedGen UID:
698522
•Concept ID:
C1275239
•
Neoplastic Process
SNOMED CT: Dermatomyofibroma (403995000)

Definition

A rare benign cutaneous mesenchymal neoplasm of fibroblastic/myofibroblastic differentiation. (WHO 2018) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDermatomyofibroma

Professional guidelines

PubMed

Dermatomyofibromas presenting in pediatric patients: clinicopathologic characteristics and differential diagnosis.
Tardío JC, Azorín D, Hernández-Núñez A, Guzmán A, Torrelo A, Herráiz M, Espinosa P, Moreno A, Granados R, Colmenero I
J Cutan Pathol 2011 Dec;38(12):967-72. Epub 2011 Jul 14 doi: 10.1111/j.1600-0560.2011.01739.x. PMID: 21752049

Recent clinical studies

Etiology

Plexiform Myofibroblastoma: Clinicopathologic Analysis of 36 Cases of a Distinctive Benign Tumor of Soft Tissue Affecting Mainly Children and Young Adults.
Papke DJ Jr, Al-Ibraheemi A, Fletcher CDM
Am J Surg Pathol 2020 Nov;44(11):1469-1478. doi: 10.1097/PAS.0000000000001534. PMID: 32618598
Dermatomyofibromas presenting in pediatric patients: clinicopathologic characteristics and differential diagnosis.
Tardío JC, Azorín D, Hernández-Núñez A, Guzmán A, Torrelo A, Herráiz M, Espinosa P, Moreno A, Granados R, Colmenero I
J Cutan Pathol 2011 Dec;38(12):967-72. Epub 2011 Jul 14 doi: 10.1111/j.1600-0560.2011.01739.x. PMID: 21752049
Dermatomyofibroma: clinicopathologic and immunohistochemical analysis of 56 cases and reappraisal of a rare and distinct cutaneous neoplasm.
Mentzel T, Kutzner H
Am J Dermatopathol 2009 Feb;31(1):44-9. doi: 10.1097/DAD.0b013e3181914e6f. PMID: 19155724
Myofibroblastic tumours: an update.
Fletcher CD
Verh Dtsch Ges Pathol 1998;82:75-82. PMID: 10095420
New entities in cutaneous soft tissue tumours.
Calonje E, Fletcher CD
Pathologica 1993 Jan-Feb;85(1095):1-15. PMID: 8390634

Diagnosis

Multiple dermatomyofibromas.
Lima LAF, Lisboa GM, Silva Filho EAD, Rabelo G
An Bras Dermatol 2018 Mar;93(2):268-270. doi: 10.1590/abd1806-4841.20186748. PMID: 29723353Free PMC Article
Dermatomyofibroma.
Campagnolo OA, Morais CF, Ughini MO, Aoki CM, Menegazzo M
An Bras Dermatol 2017 Jan-Feb;92(1):101-103. doi: 10.1590/abd1806-4841.20175189. PMID: 28225965Free PMC Article
Dermatofibrosarcoma protuberans--an update.
Breuninger H, Sebastian G, Garbe C
J Dtsch Dermatol Ges 2004 Aug;2(8):661-7. doi: 10.1046/j.1439-0353.2004.04056.x. PMID: 16279228
Dermatomyofibroma (Plaqueförmige Dermale Fibromatose).
Tani M, Komura A, Ichihashi M
J Dermatol 1997 Dec;24(12):793-7. doi: 10.1111/j.1346-8138.1997.tb02329.x. PMID: 9492446
Linear dermatomyofibroma.
Trotter MJ, McGregor GI, O'Connell JX
Clin Exp Dermatol 1996 Jul;21(4):307-9. doi: 10.1111/j.1365-2230.1996.tb00104.x. PMID: 8959908

Prognosis

Fibrous histiocytoma/dermatofibroma in children: the same as adults?
Berklite L, Ranganathan S, John I, Picarsic J, Santoro L, Alaggio R
Hum Pathol 2020 May;99:107-115. Epub 2020 Apr 1 doi: 10.1016/j.humpath.2020.03.012. PMID: 32246988
Dermatomyofibromas Arising in Children: Report of Two New Cases and Review of the Literature.
Ma JE, Wieland CN, Tollefson MM
Pediatr Dermatol 2017 May;34(3):347-351. Epub 2017 Mar 20 doi: 10.1111/pde.13104. PMID: 28318057
Dermatomyofibromas presenting in pediatric patients: clinicopathologic characteristics and differential diagnosis.
Tardío JC, Azorín D, Hernández-Núñez A, Guzmán A, Torrelo A, Herráiz M, Espinosa P, Moreno A, Granados R, Colmenero I
J Cutan Pathol 2011 Dec;38(12):967-72. Epub 2011 Jul 14 doi: 10.1111/j.1600-0560.2011.01739.x. PMID: 21752049
Dermatomyofibroma mimicking granuloma annulare.
Cano Martínez N, Fernández-Antón Martínez C, Barchino Ortiz L, Lecona Echevarría M, Campos Domínguez M
Dermatol Online J 2011 Jun 15;17(6):3. PMID: 21696683
Dermatofibrosarcoma protuberans--an update.
Breuninger H, Sebastian G, Garbe C
J Dtsch Dermatol Ges 2004 Aug;2(8):661-7. doi: 10.1046/j.1439-0353.2004.04056.x. PMID: 16279228

Clinical prediction guides

A rare case report for dermatomyofibroma in nasion.
Fu S, Zhang J, Zhan Y, Zhang H, Herman EI, Lu Q, Zhou Y, Zhang G
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Sep 28;43(9):1037-1040. doi: 10.11817/j.issn.1672-7347.2018.09.017. PMID: 30333298
A tale of two clones: Caldesmon staining in the differentiation of cutaneous spindle cell neoplasms.
Beck EM, Bauman TM, Rosman IS
J Cutan Pathol 2018 Aug;45(8):581-587. Epub 2018 May 22 doi: 10.1111/cup.13259. PMID: 29687929
New entities in cutaneous soft tissue tumours.
Calonje E, Fletcher CD
Pathologica 1993 Jan-Feb;85(1095):1-15. PMID: 8390634
Dermatomyofibroma: additional observations on a distinctive cutaneous myofibroblastic tumour with emphasis on differential diagnosis.
Mentzel T, Calonje E, Fletcher CD
Br J Dermatol 1993 Jul;129(1):69-73. doi: 10.1111/j.1365-2133.1993.tb03314.x. PMID: 8369212

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