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Epulis

MedGen UID:
82751
•Concept ID:
C0266919
•
Disease or Syndrome
Synonym: Epulides
SNOMED CT: Epulis (71708001); Localized gingival enlargement (45676007); Epulis (45676007); Gingival polyp (45676007)
 
Monarch Initiative: MONDO:0003396

Definition

A non-neoplastic nodular lesion that arises from the gingiva. [from NCI]

Professional guidelines

PubMed

Congenital Epulis: Diagnosis and Management.
Lim KH, Toner MB, Millar D, Jackson C
Ulster Med J 2023 Jan;92(1):16-18. Epub 2023 Jan 6 PMID: 36762132Free PMC Article
Histopathological analysis of the differential diagnosis of peripheral odontogenic fibroma from fibrous epulis.
Manabe K, Yakeishi M, Sakaguchi W, Saruta J, Tsukinoki K
J Oral Biosci 2019 Dec;61(4):221-225. Epub 2019 Oct 25 doi: 10.1016/j.job.2019.10.003. PMID: 31669716
New treatment strategy for granulomatous epulis: intralesional injection of propranolol.
Liu C, Qin ZP, Fan ZN, Zhao WJ, Wang YM, Wei FC, Li KL, Liu SH
Med Hypotheses 2012 Feb;78(2):327-9. Epub 2011 Nov 30 doi: 10.1016/j.mehy.2011.11.013. PMID: 22133559

Recent clinical studies

Therapy

Bleeding epulis gravidarum: what to evaluate?
Iorio GG, Carbone L, Donadono V, Rovetto MY, Sarno L, Saccone G, Mazzarelli LL, Sirico A, Esposito G, Buonfantino C, DI Girolamo R, Arduino B, D'Alessandro P, Maruotti GM
Minerva Obstet Gynecol 2022 Apr;74(2):171-177. doi: 10.23736/S2724-606X.21.04960-5. PMID: 35421917
Role of prenatal imaging in the diagnosis and management of fetal facio-cervical masses.
Zheng W, Gai S, Qin J, Qiu F, Li B, Zou Y
Sci Rep 2021 Jan 14;11(1):1385. doi: 10.1038/s41598-021-80976-4. PMID: 33446872Free PMC Article
Sclerotherapy for the recurrent granulomatous epulis with pingyangmycin.
Cai Y, Sun R, He KF, Zhao YF, Zhao JH
Med Oral Patol Oral Cir Bucal 2017 Mar 1;22(2):e214-e218. doi: 10.4317/medoral.21422. PMID: 28160580Free PMC Article
Unusual oral manifestations and evolution in glycogen storage disease type Ib.
Mortellaro C, Garagiola U, Carbone V, Cerutti F, Marci V, Bonda PL
J Craniofac Surg 2005 Jan;16(1):45-52. doi: 10.1097/00001665-200501000-00010. PMID: 15699644
Oral contraceptives and the dental practitioner.
Duxbury AJ, Leach FN
Dent Update 1982 Mar;9(2):97-9. PMID: 6959925

Prognosis

Congenital Upper Lip Sinus.
Zhang J, Li Z, Pang P
J Craniofac Surg 2024 Jul-Aug 01;35(5):e438-e441. Epub 2024 May 2 doi: 10.1097/SCS.0000000000010138. PMID: 38688013
Clinical and pathological analysis of congenital granular cell tumor.
Zheng C, Su J, Liang X, Wu J, Gu W, Zhao X
Hua Xi Kou Qiang Yi Xue Za Zhi 2022 Dec 1;40(6):710-715. doi: 10.7518/hxkq.2022.06.013. PMID: 36416325Free PMC Article
Changing indications and antenatal prognostic factors for ex-utero intrapartum treatment procedures.
Porter H, Trivedi A, Marquez M, Gibson P, Melov SJ, Mishra U, Jani P, Cheng AT, Nayyar R, Alahakoon TI
Prenat Diagn 2022 Oct;42(11):1420-1428. Epub 2022 Sep 9 doi: 10.1002/pd.6230. PMID: 36045557
Odontogenic and Developmental Oral Lesions in Pediatric Patients.
Bilodeau EA, Hunter KD
Head Neck Pathol 2021 Mar;15(1):71-84. Epub 2021 Mar 15 doi: 10.1007/s12105-020-01284-3. PMID: 33723756Free PMC Article
Granular cell tumors.
Kershisnik M, Batsakis JG, Mackay B
Ann Otol Rhinol Laryngol 1994 May;103(5 Pt 1):416-9. doi: 10.1177/000348949410300514. PMID: 8179261

Clinical prediction guides

Clinical and pathologic factors associated with the relapse of fibrous gingival hyperplasia.
Xu K, Zhu Y, Li Y, Huang J, Wan Q, Hao J, Ji Z, Liu Y, Tay FR, Jiao K, Niu L
J Am Dent Assoc 2022 Dec;153(12):1134-1144.e2. Epub 2022 Oct 25 doi: 10.1016/j.adaj.2022.08.014. PMID: 36307356
A New Look at the History of Peripheral Ameloblastoma.
Ide F, Ito Y, Miyazaki Y, Nishimura M, Kusama K, Kikuchi K
Head Neck Pathol 2020 Dec;14(4):1052-1057. Epub 2020 May 25 doi: 10.1007/s12105-020-01168-6. PMID: 32451874Free PMC Article
Comparsion of staining characteristics of Toto bodies.
Padala SS, Kiresur MA, Ananthaneni A, Guduru VS, Puneeth HK, Bhavana B
Biotech Histochem 2018;93(5):336-339. Epub 2018 May 21 doi: 10.1080/10520295.2018.1441441. PMID: 29781718
A report on the clinical-pathological correlations of 788 gingival lesion.
Gambino A, Carbone M, Broccoletti R, Carcieri P, Conrotto D, Carrozzo M, Arduino PG
Med Oral Patol Oral Cir Bucal 2017 Nov 1;22(6):e686-e693. doi: 10.4317/medoral.21845. PMID: 29053652Free PMC Article
Congenital granular cell epulis.
Conrad R, Perez MC
Arch Pathol Lab Med 2014 Jan;138(1):128-31. doi: 10.5858/arpa.2012-0306-RS. PMID: 24377822

Recent systematic reviews

Congenital Upper Lip Sinus.
Zhang J, Li Z, Pang P
J Craniofac Surg 2024 Jul-Aug 01;35(5):e438-e441. Epub 2024 May 2 doi: 10.1097/SCS.0000000000010138. PMID: 38688013

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