U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Recurrent Lip and Oral Cavity Squamous Cell Carcinoma

MedGen UID:
852486
•Concept ID:
C0280363
•
Neoplastic Process

Definition

The reemergence of lip and oral cavity squamous cell carcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Lip and Oral Cavity Squamous Cell Carcinoma

Professional guidelines

PubMed

Potential Alternative Therapeutic Modalities for Management Head and Neck Squamous Cell Carcinoma: A Review.
Afshari K, Sohal KS
Cancer Control 2023 Jan-Dec;30:10732748231185003. doi: 10.1177/10732748231185003. PMID: 37328298Free PMC Article
Interstitial Brachytherapy for Lip Cancer: Technical Aspects to Individualize Treatment Approach and Optimize Outcomes.
Merfeld EC, Witek ME, Francis DM, Burr AR, Wallace CR, Kuczmarska-Haas A, Lamichhane N, Kimple RJ, Glazer TA, Wieland AM, McCulloch TM, Hartig GK, Harari PM
Pract Radiat Oncol 2023 Jul-Aug;13(4):340-345. Epub 2023 Jan 25 doi: 10.1016/j.prro.2023.01.004. PMID: 36709044Free PMC Article
Management of high-risk squamous cell carcinoma of the skin.
Samarasinghe V, Madan V, Lear JT
Expert Rev Anticancer Ther 2011 May;11(5):763-9. doi: 10.1586/era.11.36. PMID: 21554051

Recent clinical studies

Etiology

Outcomes of Squamous Cell Carcinoma of the Lip Treated With Mohs Micrographic Surgery: A Retrospective Cohort Study.
Nadir U, Le K, Shi K, Srivastava D, Nijhawan RI
Dermatol Surg 2023 Dec 1;49(12):1108-1111. Epub 2023 Nov 1 doi: 10.1097/DSS.0000000000003992. PMID: 37910651
Clinicopathologic Characteristics of Young Patients with Oral Squamous Cell Carcinoma.
Mneimneh WS, Xu B, Ghossein C, Alzumaili B, Sethi S, Ganly I, Khimraj A, Dogan S, Katabi N
Head Neck Pathol 2021 Dec;15(4):1099-1108. Epub 2021 Apr 2 doi: 10.1007/s12105-021-01320-w. PMID: 33797696Free PMC Article
Squamous cell carcinoma of the head and neck in children.
Dombrowski ND, Wolter NE, Irace AL, Robson CD, Perez-Atayde AR, Mack JW, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 Feb;117:131-137. Epub 2018 Nov 20 doi: 10.1016/j.ijporl.2018.11.019. PMID: 30579067
High-dose-rate brachytherapy using molds for lip and oral cavity tumors.
Unetsubo T, Matsuzaki H, Takemoto M, Katsui K, Hara M, Katayama N, Waki T, Kanazawa S, Asaumi J
Radiat Oncol 2015 Apr 8;10:81. doi: 10.1186/s13014-015-0390-z. PMID: 25888772Free PMC Article
Management of high-risk squamous cell carcinoma of the skin.
Samarasinghe V, Madan V, Lear JT
Expert Rev Anticancer Ther 2011 May;11(5):763-9. doi: 10.1586/era.11.36. PMID: 21554051

Diagnosis

Clinicopathologic Characteristics of Young Patients with Oral Squamous Cell Carcinoma.
Mneimneh WS, Xu B, Ghossein C, Alzumaili B, Sethi S, Ganly I, Khimraj A, Dogan S, Katabi N
Head Neck Pathol 2021 Dec;15(4):1099-1108. Epub 2021 Apr 2 doi: 10.1007/s12105-021-01320-w. PMID: 33797696Free PMC Article
Primary Intraosseous Squamous Cell Carcinoma Involving the Jaw Bones: A Systematic Review and Update.
de Morais EF, Carlan LM, de Farias Morais HG, Pinheiro JC, Martins HDD, Barboza CAG, de Almeida Freitas R
Head Neck Pathol 2021 Jun;15(2):608-616. Epub 2020 Oct 12 doi: 10.1007/s12105-020-01234-z. PMID: 33044723Free PMC Article
Squamous cell carcinoma of the head and neck in children.
Dombrowski ND, Wolter NE, Irace AL, Robson CD, Perez-Atayde AR, Mack JW, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 Feb;117:131-137. Epub 2018 Nov 20 doi: 10.1016/j.ijporl.2018.11.019. PMID: 30579067
Congenital epulis.
Merglová V, Mukensnabl P, Andrle P
BMJ Case Rep 2012 Jul 9;2012 doi: 10.1136/bcr.01.2012.5483. PMID: 22778448Free PMC Article
Management of high-risk squamous cell carcinoma of the skin.
Samarasinghe V, Madan V, Lear JT
Expert Rev Anticancer Ther 2011 May;11(5):763-9. doi: 10.1586/era.11.36. PMID: 21554051

Therapy

5-Aminolevulinic acid photodynamic therapy for early-stage lip squamous cell carcinoma.
Wang P, Zhang G, Zhang L, Zhou Z, Shi L, Zeng Q, Zhu L, Wang X
Photodiagnosis Photodyn Ther 2021 Sep;35:102321. Epub 2021 May 17 doi: 10.1016/j.pdpdt.2021.102321. PMID: 34015543
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).
Cohen EEW, Bell RB, Bifulco CB, Burtness B, Gillison ML, Harrington KJ, Le QT, Lee NY, Leidner R, Lewis RL, Licitra L, Mehanna H, Mell LK, Raben A, Sikora AG, Uppaluri R, Whitworth F, Zandberg DP, Ferris RL
J Immunother Cancer 2019 Jul 15;7(1):184. doi: 10.1186/s40425-019-0662-5. PMID: 31307547Free PMC Article
Squamous cell carcinoma of the head and neck in children.
Dombrowski ND, Wolter NE, Irace AL, Robson CD, Perez-Atayde AR, Mack JW, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 Feb;117:131-137. Epub 2018 Nov 20 doi: 10.1016/j.ijporl.2018.11.019. PMID: 30579067
High-dose-rate brachytherapy using molds for lip and oral cavity tumors.
Unetsubo T, Matsuzaki H, Takemoto M, Katsui K, Hara M, Katayama N, Waki T, Kanazawa S, Asaumi J
Radiat Oncol 2015 Apr 8;10:81. doi: 10.1186/s13014-015-0390-z. PMID: 25888772Free PMC Article
Management of high-risk squamous cell carcinoma of the skin.
Samarasinghe V, Madan V, Lear JT
Expert Rev Anticancer Ther 2011 May;11(5):763-9. doi: 10.1586/era.11.36. PMID: 21554051

Prognosis

Outcomes of Squamous Cell Carcinoma of the Lip Treated With Mohs Micrographic Surgery: A Retrospective Cohort Study.
Nadir U, Le K, Shi K, Srivastava D, Nijhawan RI
Dermatol Surg 2023 Dec 1;49(12):1108-1111. Epub 2023 Nov 1 doi: 10.1097/DSS.0000000000003992. PMID: 37910651
Clinicopathologic Characteristics of Young Patients with Oral Squamous Cell Carcinoma.
Mneimneh WS, Xu B, Ghossein C, Alzumaili B, Sethi S, Ganly I, Khimraj A, Dogan S, Katabi N
Head Neck Pathol 2021 Dec;15(4):1099-1108. Epub 2021 Apr 2 doi: 10.1007/s12105-021-01320-w. PMID: 33797696Free PMC Article
Primary Intraosseous Squamous Cell Carcinoma Involving the Jaw Bones: A Systematic Review and Update.
de Morais EF, Carlan LM, de Farias Morais HG, Pinheiro JC, Martins HDD, Barboza CAG, de Almeida Freitas R
Head Neck Pathol 2021 Jun;15(2):608-616. Epub 2020 Oct 12 doi: 10.1007/s12105-020-01234-z. PMID: 33044723Free PMC Article
Evaluation and Prognostic Significance of Galectin-3 Expression in Oral Squamous Cell Carcinoma.
Tokmak S, Arık D, Pınarbaşlı Ö, Gürbüz MK, Açıkalın MF
Ear Nose Throat J 2021 Sep;100(5_suppl):578S-583S. Epub 2019 Dec 15 doi: 10.1177/0145561319893861. PMID: 31838918
Management of high-risk squamous cell carcinoma of the skin.
Samarasinghe V, Madan V, Lear JT
Expert Rev Anticancer Ther 2011 May;11(5):763-9. doi: 10.1586/era.11.36. PMID: 21554051

Clinical prediction guides

Clinical and pathological correlation of P(53) expression in oral cancers.
Ravishankar B, Madhavi BV, Kalagara A, Bodepudi S, Harnadh S, Bindu PJ, Pydi VR, Raj BP, Nitya G, Rishik B
Pathol Res Pract 2024 Jan;253:155071. Epub 2023 Dec 29 doi: 10.1016/j.prp.2023.155071. PMID: 38181580
Evaluation and Prognostic Significance of Galectin-3 Expression in Oral Squamous Cell Carcinoma.
Tokmak S, Arık D, Pınarbaşlı Ö, Gürbüz MK, Açıkalın MF
Ear Nose Throat J 2021 Sep;100(5_suppl):578S-583S. Epub 2019 Dec 15 doi: 10.1177/0145561319893861. PMID: 31838918
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).
Cohen EEW, Bell RB, Bifulco CB, Burtness B, Gillison ML, Harrington KJ, Le QT, Lee NY, Leidner R, Lewis RL, Licitra L, Mehanna H, Mell LK, Raben A, Sikora AG, Uppaluri R, Whitworth F, Zandberg DP, Ferris RL
J Immunother Cancer 2019 Jul 15;7(1):184. doi: 10.1186/s40425-019-0662-5. PMID: 31307547Free PMC Article
The stem cell markers expression CD44v6 and podoplanin in lip cancer: clinical significance.
Garcia AS, Assao A, Carvalho AL, Soares FA, Kowalski LP, Oliveira DT
Virchows Arch 2019 Jun;474(6):745-754. Epub 2019 Feb 15 doi: 10.1007/s00428-019-02539-3. PMID: 30770986
Squamous cell carcinoma of the lip. A retrospective study of 146 patients.
Gutiérrez-Pascual M, Vicente-Martín FJ, Fernández-Álvarez JG, Martín-López R, Pinedo-Moraleda F, López-Estebaranz JL
J Eur Acad Dermatol Venereol 2012 Sep;26(9):1116-21. Epub 2011 Sep 19 doi: 10.1111/j.1468-3083.2011.04227.x. PMID: 21923660

Recent systematic reviews

Primary Intraosseous Squamous Cell Carcinoma Involving the Jaw Bones: A Systematic Review and Update.
de Morais EF, Carlan LM, de Farias Morais HG, Pinheiro JC, Martins HDD, Barboza CAG, de Almeida Freitas R
Head Neck Pathol 2021 Jun;15(2):608-616. Epub 2020 Oct 12 doi: 10.1007/s12105-020-01234-z. PMID: 33044723Free PMC Article
Identifying risk factors for the prognosis of head and neck cutaneous squamous cell carcinoma: A systematic review and meta-analysis.
Zeng S, Fu L, Zhou P, Ling H
PLoS One 2020;15(9):e0239586. Epub 2020 Sep 29 doi: 10.1371/journal.pone.0239586. PMID: 32991600Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...