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Oversedated

MedGen UID:
852661
•Concept ID:
C0542127
•
Finding
Synonym: Oversedation

Definition

A level of sedation that is greater than the intended level. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOversedated

Professional guidelines

PubMed

Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients.
Fleming MF, Davis J, Passik SD
Pain Med 2008 Nov;9(8):1098-106. Epub 2008 Aug 18 doi: 10.1111/j.1526-4637.2008.00491.x. PMID: 18721174Free PMC Article

Recent clinical studies

Etiology

Evaluation of Nonintubated Analgesia Practices in Critical Care Transport.
Esteves AM, Gilchrist HE, Markwood JM, Bondurant M, Roginski MA
Air Med J 2023 Jul-Aug;42(4):259-262. Epub 2023 Apr 14 doi: 10.1016/j.amj.2023.03.006. PMID: 37356886
The Effectiveness of α2 Agonists As Sedatives in Pediatric Critical Care: A Propensity Score-Matched Cohort Study.
Hayden JC, Doherty DR, Dawkins I, Leacy FP, Healy M, Breatnach CV, Cousins G, Gallagher PJ
Crit Care Med 2019 Jul;47(7):e580-e586. doi: 10.1097/CCM.0000000000003789. PMID: 31033500
Exploring Antipsychotic Prescribing Behaviors for Nursing Home Residents With Dementia: A Qualitative Study.
Walsh KA, Sinnott C, Fleming A, Mc Sharry J, Byrne S, Browne J, Timmons S
J Am Med Dir Assoc 2018 Nov;19(11):948-958.e12. Epub 2018 Sep 18 doi: 10.1016/j.jamda.2018.07.004. PMID: 30241987
Psychotropic Drug Use in Physically Restrained, Critically Ill Adults Receiving Mechanical Ventilation.
Guenette M, Burry L, Cheung A, Farquharson T, Traille M, Mantas I, Mehta S, Rose L
Am J Crit Care 2017 Sep;26(5):380-387. doi: 10.4037/ajcc2017677. PMID: 28864434
Identification of acute brain failure using electronic medical records.
Reddy DR, Singh TD, Guru PK, Sakusic A, Gajic O, O'Horo JC, Rabinstein AA
J Crit Care 2016 Aug;34:12-6. Epub 2016 Mar 16 doi: 10.1016/j.jcrc.2016.03.008. PMID: 27288602Free PMC Article

Diagnosis

Changes in public order after the opening of an overdose monitoring facility for people who inject drugs.
León C, Cardoso LJP, Johnston S, Mackin S, Bock B, Gaeta JM
Int J Drug Policy 2018 Mar;53:90-95. Epub 2018 Jan 2 doi: 10.1016/j.drugpo.2017.12.009. PMID: 29294417
Identification of acute brain failure using electronic medical records.
Reddy DR, Singh TD, Guru PK, Sakusic A, Gajic O, O'Horo JC, Rabinstein AA
J Crit Care 2016 Aug;34:12-6. Epub 2016 Mar 16 doi: 10.1016/j.jcrc.2016.03.008. PMID: 27288602Free PMC Article
Methadone conversion in infants and children: Retrospective cohort study of 199 pediatric inpatients.
Fife A, Postier A, Flood A, Friedrichsdorf SJ
J Opioid Manag 2016 May-Jun;12(2):123-30. doi: 10.5055/jom.2016.0324. PMID: 27194197
Comparison of two ketamine-propofol dosing regimens for sedation during interventional radiology procedures.
Erden IA, Pamuk AG, Akinci SB, Koseoglu A, Aypar U
Minerva Anestesiol 2010 Apr;76(4):260-5. Epub 2009 Nov 24 PMID: 20332739
The COMFORT behavioural scale and the modified FLACC scale in paediatric intensive care.
Johansson M, Kokinsky E
Nurs Crit Care 2009 May-Jun;14(3):122-30. doi: 10.1111/j.1478-5153.2009.00323.x. PMID: 19366409

Therapy

Evaluation of Nonintubated Analgesia Practices in Critical Care Transport.
Esteves AM, Gilchrist HE, Markwood JM, Bondurant M, Roginski MA
Air Med J 2023 Jul-Aug;42(4):259-262. Epub 2023 Apr 14 doi: 10.1016/j.amj.2023.03.006. PMID: 37356886
Personalized sedation goal for agitated delirium in patients with cancer: Balancing comfort and communication.
Hui D, De La Rosa A, Urbauer DL, Nguyen T, Bruera E
Cancer 2021 Dec 15;127(24):4694-4701. Epub 2021 Aug 25 doi: 10.1002/cncr.33876. PMID: 34432293Free PMC Article
The Effectiveness of α2 Agonists As Sedatives in Pediatric Critical Care: A Propensity Score-Matched Cohort Study.
Hayden JC, Doherty DR, Dawkins I, Leacy FP, Healy M, Breatnach CV, Cousins G, Gallagher PJ
Crit Care Med 2019 Jul;47(7):e580-e586. doi: 10.1097/CCM.0000000000003789. PMID: 31033500
Exploring Antipsychotic Prescribing Behaviors for Nursing Home Residents With Dementia: A Qualitative Study.
Walsh KA, Sinnott C, Fleming A, Mc Sharry J, Byrne S, Browne J, Timmons S
J Am Med Dir Assoc 2018 Nov;19(11):948-958.e12. Epub 2018 Sep 18 doi: 10.1016/j.jamda.2018.07.004. PMID: 30241987
Psychotropic Drug Use in Physically Restrained, Critically Ill Adults Receiving Mechanical Ventilation.
Guenette M, Burry L, Cheung A, Farquharson T, Traille M, Mantas I, Mehta S, Rose L
Am J Crit Care 2017 Sep;26(5):380-387. doi: 10.4037/ajcc2017677. PMID: 28864434

Prognosis

Personalized sedation goal for agitated delirium in patients with cancer: Balancing comfort and communication.
Hui D, De La Rosa A, Urbauer DL, Nguyen T, Bruera E
Cancer 2021 Dec 15;127(24):4694-4701. Epub 2021 Aug 25 doi: 10.1002/cncr.33876. PMID: 34432293Free PMC Article
Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients.
Fleming MF, Davis J, Passik SD
Pain Med 2008 Nov;9(8):1098-106. Epub 2008 Aug 18 doi: 10.1111/j.1526-4637.2008.00491.x. PMID: 18721174Free PMC Article
Epidemiology of sedation and sedation adequacy for mechanically ventilated patients in a medical and surgical intensive care unit.
Weinert CR, Calvin AD
Crit Care Med 2007 Feb;35(2):393-401. doi: 10.1097/01.CCM.0000254339.18639.1D. PMID: 17205015

Clinical prediction guides

Personalized sedation goal for agitated delirium in patients with cancer: Balancing comfort and communication.
Hui D, De La Rosa A, Urbauer DL, Nguyen T, Bruera E
Cancer 2021 Dec 15;127(24):4694-4701. Epub 2021 Aug 25 doi: 10.1002/cncr.33876. PMID: 34432293Free PMC Article
The Effectiveness of α2 Agonists As Sedatives in Pediatric Critical Care: A Propensity Score-Matched Cohort Study.
Hayden JC, Doherty DR, Dawkins I, Leacy FP, Healy M, Breatnach CV, Cousins G, Gallagher PJ
Crit Care Med 2019 Jul;47(7):e580-e586. doi: 10.1097/CCM.0000000000003789. PMID: 31033500
Psychotropic Drug Use in Physically Restrained, Critically Ill Adults Receiving Mechanical Ventilation.
Guenette M, Burry L, Cheung A, Farquharson T, Traille M, Mantas I, Mehta S, Rose L
Am J Crit Care 2017 Sep;26(5):380-387. doi: 10.4037/ajcc2017677. PMID: 28864434
Identification of acute brain failure using electronic medical records.
Reddy DR, Singh TD, Guru PK, Sakusic A, Gajic O, O'Horo JC, Rabinstein AA
J Crit Care 2016 Aug;34:12-6. Epub 2016 Mar 16 doi: 10.1016/j.jcrc.2016.03.008. PMID: 27288602Free PMC Article
The COMFORT behavioural scale and the modified FLACC scale in paediatric intensive care.
Johansson M, Kokinsky E
Nurs Crit Care 2009 May-Jun;14(3):122-30. doi: 10.1111/j.1478-5153.2009.00323.x. PMID: 19366409

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