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Abnormal tympanic membrane morphology

MedGen UID:
868056
•Concept ID:
C4022447
•
Finding
Synonyms: Abnormality of the eardrum; Abnormality of the tympanic membrane
 
HPO: HP:0040090

Definition

Any structural abnormality of the tympanic membrane [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal tympanic membrane morphology

Professional guidelines

PubMed

Assessment and management of retraction pockets.
Alper C, Olszewska E
Otolaryngol Pol 2017 Feb 28;71(1):1-21. doi: 10.5604/01.3001.0009.5547. PMID: 28485292
Clinical practice guidelines for the diagnosis and management of otitis media with effusion (OME) in children in Japan, 2015.
Ito M, Takahashi H, Iino Y, Kojima H, Hashimoto S, Kamide Y, Kudo F, Kobayashi H, Kuroki H, Nakano A, Hidaka H, Takahashi G, Yoshida H, Nakayama T
Auris Nasus Larynx 2017 Oct;44(5):501-508. Epub 2017 May 1 doi: 10.1016/j.anl.2017.03.018. PMID: 28473270
Management of Conductive Hearing Loss in Children.
Dougherty W, Kesser BW
Otolaryngol Clin North Am 2015 Dec;48(6):955-74. Epub 2015 Sep 8 doi: 10.1016/j.otc.2015.06.007. PMID: 26360369

Recent clinical studies

Etiology

Otosclerosis under the magnifying glass.
Bălaşa Vîrzob CR, Cloşca RM, Poenaru M, Morar R, Balica NC, Sarău CA, Ioniţă I, Baderca F
Rom J Morphol Embryol 2023 Apr-Jun;64(2):189-197. doi: 10.47162/RJME.64.2.09. PMID: 37518876Free PMC Article
Otitis media.
Schilder AG, Chonmaitree T, Cripps AW, Rosenfeld RM, Casselbrant ML, Haggard MP, Venekamp RP
Nat Rev Dis Primers 2016 Sep 8;2(1):16063. doi: 10.1038/nrdp.2016.63. PMID: 27604644Free PMC Article
Surgical anatomy and pathology of the middle ear.
Luers JC, Hüttenbrink KB
J Anat 2016 Feb;228(2):338-53. Epub 2015 Oct 19 doi: 10.1111/joa.12389. PMID: 26482007Free PMC Article
The contralateral ear in cholesteatoma.
da Costa SS, Teixeira AR, Rosito LP
Eur Arch Otorhinolaryngol 2016 Jul;273(7):1717-21. Epub 2015 Jul 30 doi: 10.1007/s00405-015-3736-0. PMID: 26223352
Stapedectomy in children.
House JW, Sheehy JL, Antunez JC
Laryngoscope 1980 Nov;90(11 Pt 1):1804-9. doi: 10.1288/00005537-198011000-00007. PMID: 7432061

Diagnosis

Otosclerosis under the magnifying glass.
Bălaşa Vîrzob CR, Cloşca RM, Poenaru M, Morar R, Balica NC, Sarău CA, Ioniţă I, Baderca F
Rom J Morphol Embryol 2023 Apr-Jun;64(2):189-197. doi: 10.47162/RJME.64.2.09. PMID: 37518876Free PMC Article
Otitis media.
Schilder AG, Chonmaitree T, Cripps AW, Rosenfeld RM, Casselbrant ML, Haggard MP, Venekamp RP
Nat Rev Dis Primers 2016 Sep 8;2(1):16063. doi: 10.1038/nrdp.2016.63. PMID: 27604644Free PMC Article
Congenital Cholesteatoma.
Walker D, Shinners MJ
Pediatr Ann 2016 May 1;45(5):e167-70. doi: 10.3928/00904481-20160401-01. PMID: 27171804
Smith-McGuckin spot.
Smith CW
J R Soc Med 1985 Jan;78(1):18-26. doi: 10.1177/014107688507800105. PMID: 4038519Free PMC Article
Tympanometry.
Shanks JE
Ear Hear 1984 Sep-Oct;5(5):268-80. doi: 10.1097/00003446-198409000-00003. PMID: 6542036

Therapy

Conductive hearing loss with a "dry middle ear cleft"-A comprehensive pictorial review with CT.
Nguyen T, Pulickal G, Singh A, Lingam R
Eur J Radiol 2019 Jan;110:74-80. Epub 2018 Nov 22 doi: 10.1016/j.ejrad.2018.11.024. PMID: 30599877
Clinical practice guidelines for the diagnosis and management of otitis media with effusion (OME) in children in Japan, 2015.
Ito M, Takahashi H, Iino Y, Kojima H, Hashimoto S, Kamide Y, Kudo F, Kobayashi H, Kuroki H, Nakano A, Hidaka H, Takahashi G, Yoshida H, Nakayama T
Auris Nasus Larynx 2017 Oct;44(5):501-508. Epub 2017 May 1 doi: 10.1016/j.anl.2017.03.018. PMID: 28473270
Otitis media.
Schilder AG, Chonmaitree T, Cripps AW, Rosenfeld RM, Casselbrant ML, Haggard MP, Venekamp RP
Nat Rev Dis Primers 2016 Sep 8;2(1):16063. doi: 10.1038/nrdp.2016.63. PMID: 27604644Free PMC Article
A meta-analysis of the long-term hearing outcomes and complications associated with atresiaplasty.
Li CL, Dai PD, Yang L, Zhang TY
Int J Pediatr Otorhinolaryngol 2015 Jun;79(6):793-797. Epub 2015 Apr 9 doi: 10.1016/j.ijporl.2015.03.032. PMID: 25912684
Tympanic membrane changes in central tympanic membrane perforations.
Oktay MF, Cureoglu S, Schachern PA, Paparella MM, Kariya S, Fukushima H
Am J Otolaryngol 2005 Nov-Dec;26(6):393-7. doi: 10.1016/j.amjoto.2005.05.005. PMID: 16275408

Prognosis

Isolated Incudostapedial Cholesteatomas: Unique Radiologic and Surgical Features.
MacDonald B, Bommakanti K, Mallo M, Carvalho D
Ear Nose Throat J 2021 Jun;100(3_suppl):243S-248S. Epub 2020 Nov 25 doi: 10.1177/0145561320973785. PMID: 33237827
Paper patching for patulous eustachian tube.
Kim SJ, Shin SA, Lee HY, Park YH
Acta Otolaryngol 2019 Feb;139(2):122-128. Epub 2019 Feb 14 doi: 10.1080/00016489.2018.1541505. PMID: 30762451
Membranous band between the tympanic membrane and the external auditory canal.
Kimitsuki T
Int J Pediatr Otorhinolaryngol 2014 Apr;78(4):690-2. Epub 2014 Jan 23 doi: 10.1016/j.ijporl.2014.01.017. PMID: 24525023
Persistent otorrhoea with an abnormal tympanic membrane secondary to squamous cell carcinoma of the tympanic membrane.
de Zoysa N, Stephens J, Mochloulis GM, Kothari PB
J Laryngol Otol 2011 Mar;125(3):318-20. Epub 2010 Oct 29 doi: 10.1017/S0022215110002203. PMID: 21029503
Smith-McGuckin spot.
Smith CW
J R Soc Med 1985 Jan;78(1):18-26. doi: 10.1177/014107688507800105. PMID: 4038519Free PMC Article

Clinical prediction guides

Otosclerosis under the magnifying glass.
Bălaşa Vîrzob CR, Cloşca RM, Poenaru M, Morar R, Balica NC, Sarău CA, Ioniţă I, Baderca F
Rom J Morphol Embryol 2023 Apr-Jun;64(2):189-197. doi: 10.47162/RJME.64.2.09. PMID: 37518876Free PMC Article
Correlation of Blast-Induced Tympanic Membrane Perforation with Peripheral Cochlear Synaptopathy.
Kurioka T, Mizutari K, Satoh Y, Shiotani A
J Neurotrauma 2022 Jul;39(13-14):999-1009. Epub 2022 Apr 4 doi: 10.1089/neu.2021.0487. PMID: 35243914
Membranous band between the tympanic membrane and the external auditory canal.
Kimitsuki T
Int J Pediatr Otorhinolaryngol 2014 Apr;78(4):690-2. Epub 2014 Jan 23 doi: 10.1016/j.ijporl.2014.01.017. PMID: 24525023
Structural tympanic membrane changes in secretory otitis media and cholesteatoma.
Knutsson J, Bagger-Sjöbäck D, von Unge M
Otol Neurotol 2011 Jun;32(4):596-601. doi: 10.1097/MAO.0b013e318214ea62. PMID: 21765386
Tympanic membrane changes in central tympanic membrane perforations.
Oktay MF, Cureoglu S, Schachern PA, Paparella MM, Kariya S, Fukushima H
Am J Otolaryngol 2005 Nov-Dec;26(6):393-7. doi: 10.1016/j.amjoto.2005.05.005. PMID: 16275408

Recent systematic reviews

Spontaneous Congenital Perilabyrinthine Cerebrospinal Fluid Fistulas.
Lovin BD, Appelbaum EN, Makoshi L, Whitehead WE, Sweeney AD
Ann Otol Rhinol Laryngol 2021 Dec;130(12):1360-1368. Epub 2021 Apr 9 doi: 10.1177/00034894211007242. PMID: 33834882
Middle ear congenital cholesteatoma: systematic review, meta-analysis and insights on its pathogenesis.
Gilberto N, Custódio S, Colaço T, Santos R, Sousa P, Escada P
Eur Arch Otorhinolaryngol 2020 Apr;277(4):987-998. Epub 2020 Jan 18 doi: 10.1007/s00405-020-05792-4. PMID: 31955213

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