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1-5 finger syndactyly

MedGen UID:
869302
•Concept ID:
C4023728
•
Congenital Abnormality
Synonyms: Webbed 1-5 fingers; Webbed 1st-5th fingers
 
HPO: HP:0010708

Definition

Syndactyly with fusion of fingers one to five (complete syndactyly of all fingers of the hand). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGV1-5 finger syndactyly

Conditions with this feature

Syndactyly type 4
MedGen UID:
350013
•Concept ID:
C1861355
•
Disease or Syndrome
Syndactyly type IV (SDTY4) is characterized by complete syndactylism of all the fingers accompanied by polydactyly and cup-shaped hands due to flexion of the fingers (summary by Sato et al., 2007).
See: Condition Record
Syndactyly type 4

Recent clinical studies

Etiology

Syndactyly release: a comparison of skin graft versus graftless techniques in the same patient.
Wang AA, Hutchinson DT
J Hand Surg Eur Vol 2019 Oct;44(8):845-849. Epub 2019 May 16 doi: 10.1177/1753193419848989. PMID: 31096828
ORAL-FACIAL-DIGITAL SYNDROME TYPE I (CLINICAL CASE).
Horlenko O, Lenchenko A, Kossey G, Tomey A, Debretseni O
Georgian Med News 2018 Dec;(285):47-51. PMID: 30702069
Five- and 10-Year Follow-Up of Nonvascularized Toe Phalanx Transfers.
Kawabata H, Tamura D
J Hand Surg Am 2018 May;43(5):485.e1-485.e5. Epub 2017 Dec 6 doi: 10.1016/j.jhsa.2017.10.034. PMID: 29223628
Dorsal plane-shaped advancement flap for the reconstruction of web space in syndactyly without skin grafting: A preliminary report.
Liu J, Zheng H, Chen Z, Dai X, Schilling AF, Machens HG
J Plast Reconstr Aesthet Surg 2015 Nov;68(11):e167-73. Epub 2015 Jun 27 doi: 10.1016/j.bjps.2015.06.016. PMID: 26190763
Complex syndactyly: aesthetic and objective outcomes.
Goldfarb CA, Steffen JA, Stutz CM
J Hand Surg Am 2012 Oct;37(10):2068-73. Epub 2012 Aug 31 doi: 10.1016/j.jhsa.2012.06.033. PMID: 22939825

Diagnosis

ORAL-FACIAL-DIGITAL SYNDROME TYPE I (CLINICAL CASE).
Horlenko O, Lenchenko A, Kossey G, Tomey A, Debretseni O
Georgian Med News 2018 Dec;(285):47-51. PMID: 30702069

Therapy

Syndactyly release: a comparison of skin graft versus graftless techniques in the same patient.
Wang AA, Hutchinson DT
J Hand Surg Eur Vol 2019 Oct;44(8):845-849. Epub 2019 May 16 doi: 10.1177/1753193419848989. PMID: 31096828
ORAL-FACIAL-DIGITAL SYNDROME TYPE I (CLINICAL CASE).
Horlenko O, Lenchenko A, Kossey G, Tomey A, Debretseni O
Georgian Med News 2018 Dec;(285):47-51. PMID: 30702069

Prognosis

Syndactyly release: a comparison of skin graft versus graftless techniques in the same patient.
Wang AA, Hutchinson DT
J Hand Surg Eur Vol 2019 Oct;44(8):845-849. Epub 2019 May 16 doi: 10.1177/1753193419848989. PMID: 31096828
Five- and 10-Year Follow-Up of Nonvascularized Toe Phalanx Transfers.
Kawabata H, Tamura D
J Hand Surg Am 2018 May;43(5):485.e1-485.e5. Epub 2017 Dec 6 doi: 10.1016/j.jhsa.2017.10.034. PMID: 29223628
Bhlha9 regulates apical ectodermal ridge formation during limb development.
Kataoka K, Matsushima T, Ito Y, Sato T, Yokoyama S, Asahara H
J Bone Miner Metab 2018 Jan;36(1):64-72. Epub 2017 Mar 21 doi: 10.1007/s00774-017-0820-0. PMID: 28324176Free PMC Article
Dorsal plane-shaped advancement flap for the reconstruction of web space in syndactyly without skin grafting: A preliminary report.
Liu J, Zheng H, Chen Z, Dai X, Schilling AF, Machens HG
J Plast Reconstr Aesthet Surg 2015 Nov;68(11):e167-73. Epub 2015 Jun 27 doi: 10.1016/j.bjps.2015.06.016. PMID: 26190763
The preliminary outcome of syndactyly management in children with a new external separation device.
Mei H, Zhu G, He R, Liu K, Wu J, Tang J
J Pediatr Orthop B 2015 Jan;24(1):56-62. doi: 10.1097/BPB.0000000000000116. PMID: 25387062

Clinical prediction guides

Syndactyly release: a comparison of skin graft versus graftless techniques in the same patient.
Wang AA, Hutchinson DT
J Hand Surg Eur Vol 2019 Oct;44(8):845-849. Epub 2019 May 16 doi: 10.1177/1753193419848989. PMID: 31096828
Bhlha9 regulates apical ectodermal ridge formation during limb development.
Kataoka K, Matsushima T, Ito Y, Sato T, Yokoyama S, Asahara H
J Bone Miner Metab 2018 Jan;36(1):64-72. Epub 2017 Mar 21 doi: 10.1007/s00774-017-0820-0. PMID: 28324176Free PMC Article
The preliminary outcome of syndactyly management in children with a new external separation device.
Mei H, Zhu G, He R, Liu K, Wu J, Tang J
J Pediatr Orthop B 2015 Jan;24(1):56-62. doi: 10.1097/BPB.0000000000000116. PMID: 25387062
Complex syndactyly: aesthetic and objective outcomes.
Goldfarb CA, Steffen JA, Stutz CM
J Hand Surg Am 2012 Oct;37(10):2068-73. Epub 2012 Aug 31 doi: 10.1016/j.jhsa.2012.06.033. PMID: 22939825

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