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Speech disorder

MedGen UID:
11531
•Concept ID:
C0037822
•
Disease or Syndrome
Synonym: Speech Disorders
 
Monarch Initiative: MONDO:0004730

Definition

A term referring to disorders characterized by the disruption of normal speech. It includes stuttering, lisps, dysarthria and voice disorders. [from NCI]

Professional guidelines

PubMed

Speech disorders in Parkinson's disease: pathophysiology, medical management and surgical approaches.
Dashtipour K, Tafreshi A, Lee J, Crawley B
Neurodegener Dis Manag 2018 Oct;8(5):337-348. Epub 2018 Sep 18 doi: 10.2217/nmt-2018-0021. PMID: 30223711
Contemporary Approaches to the Management of Post-stroke Apraxia of Speech.
Basilakos A
Semin Speech Lang 2018 Feb;39(1):25-36. Epub 2018 Jan 22 doi: 10.1055/s-0037-1608853. PMID: 29359303Free PMC Article
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT): Characteristics, treatment and outcome in 251 cases from the literature.
Laurent C, Capron J, Quillerou B, Thomas G, Alamowitch S, Fain O, Mekinian A
Autoimmun Rev 2016 Dec;15(12):1129-1133. Epub 2016 Sep 15 doi: 10.1016/j.autrev.2016.09.008. PMID: 27639840

Recent clinical studies

Etiology

Infant microbes and metabolites point to childhood neurodevelopmental disorders.
Ahrens AP, Hyötyläinen T, Petrone JR, Igelström K, George CD, Garrett TJ, Orešič M, Triplett EW, Ludvigsson J
Cell 2024 Apr 11;187(8):1853-1873.e15. Epub 2024 Apr 3 doi: 10.1016/j.cell.2024.02.035. PMID: 38574728
Stroke and COVID19: Not only a large-vessel disease.
Frisullo G, Bellavia S, Scala I, Piano C, Morosetti R, Brunetti V, Calabresi P, Della Marca G
J Stroke Cerebrovasc Dis 2020 Oct;29(10):105074. Epub 2020 Jun 19 doi: 10.1016/j.jstrokecerebrovasdis.2020.105074. PMID: 32912559Free PMC Article
Genetic pathways involved in human speech disorders.
den Hoed J, Fisher SE
Curr Opin Genet Dev 2020 Dec;65:103-111. Epub 2020 Jul 1 doi: 10.1016/j.gde.2020.05.012. PMID: 32622339
Refining the Phenotype of Recurrent Rearrangements of Chromosome 16.
Redaelli S, Maitz S, Crosti F, Sala E, Villa N, Spaccini L, Selicorni A, Rigoldi M, Conconi D, Dalprà L, Roversi G, Bentivegna A
Int J Mol Sci 2019 Mar 4;20(5) doi: 10.3390/ijms20051095. PMID: 30836598Free PMC Article
Disorders of communication: dysarthria.
Enderby P
Handb Clin Neurol 2013;110:273-81. doi: 10.1016/B978-0-444-52901-5.00022-8. PMID: 23312647

Diagnosis

Infant microbes and metabolites point to childhood neurodevelopmental disorders.
Ahrens AP, Hyötyläinen T, Petrone JR, Igelström K, George CD, Garrett TJ, Orešič M, Triplett EW, Ludvigsson J
Cell 2024 Apr 11;187(8):1853-1873.e15. Epub 2024 Apr 3 doi: 10.1016/j.cell.2024.02.035. PMID: 38574728
An Update on Apraxia of Speech.
Utianski RL, Josephs KA
Curr Neurol Neurosci Rep 2023 Jul;23(7):353-359. Epub 2023 Jun 3 doi: 10.1007/s11910-023-01275-1. PMID: 37269450Free PMC Article
Genetic pathways involved in human speech disorders.
den Hoed J, Fisher SE
Curr Opin Genet Dev 2020 Dec;65:103-111. Epub 2020 Jul 1 doi: 10.1016/j.gde.2020.05.012. PMID: 32622339
Surgical speech disorders.
Shen T, Sie KC
Facial Plast Surg Clin North Am 2014 Nov;22(4):593-609. Epub 2014 Nov 8 doi: 10.1016/j.fsc.2014.07.010. PMID: 25444731
Disorders of communication: dysarthria.
Enderby P
Handb Clin Neurol 2013;110:273-81. doi: 10.1016/B978-0-444-52901-5.00022-8. PMID: 23312647

Therapy

Bilateral Medial Medullary Infarct with Unique Radiological Presentation.
Çakmakci G, Çetiner M, Uysal N, Arikan FA, Kabay SC
Acta Neurol Taiwan 2024 Mar 30;33(1):13-16. doi: 10.4103/ANT.33-1_111_0017. PMID: 37848233
The effect of ankyloglossia and tongue-tie division on speech articulation: A systematic review.
Wang J, Yang X, Hao S, Wang Y
Int J Paediatr Dent 2022 Mar;32(2):144-156. Epub 2021 May 22 doi: 10.1111/ipd.12802. PMID: 33964037
Cerebellar mutism syndrome.
Catsman-Berrevoets C, Patay Z
Handb Clin Neurol 2018;155:273-288. doi: 10.1016/B978-0-444-64189-2.00018-4. PMID: 29891065
Stuttering: Clinical and research update.
Perez HR, Stoeckle JH
Can Fam Physician 2016 Jun;62(6):479-84. PMID: 27303004Free PMC Article
Retigabine: in partial seizures.
Plosker GL, Scott LJ
CNS Drugs 2006;20(7):601-8; discussion 609-10. doi: 10.2165/00023210-200620070-00005. PMID: 16800718

Prognosis

Infant microbes and metabolites point to childhood neurodevelopmental disorders.
Ahrens AP, Hyötyläinen T, Petrone JR, Igelström K, George CD, Garrett TJ, Orešič M, Triplett EW, Ludvigsson J
Cell 2024 Apr 11;187(8):1853-1873.e15. Epub 2024 Apr 3 doi: 10.1016/j.cell.2024.02.035. PMID: 38574728
Primary Progressive Aphasias and Apraxia of Speech.
Botha H, Josephs KA
Continuum (Minneap Minn) 2019 Feb;25(1):101-127. doi: 10.1212/CON.0000000000000699. PMID: 30707189Free PMC Article
Voice alterations in patients with Morquio A syndrome.
Szklanny K, Gubrynowicz R, Tylki-Szymańska A
J Appl Genet 2018 Feb;59(1):73-80. Epub 2017 Dec 23 doi: 10.1007/s13353-017-0421-6. PMID: 29275451Free PMC Article
Aphasia and thalamotomy: important issues.
Bruce BB, Foote KD, Rosenbek J, Sapienza C, Romrell J, Crucian G, Okun MS
Stereotact Funct Neurosurg 2004;82(4):186-90. Epub 2004 Nov 18 doi: 10.1159/000082207. PMID: 15557767
What causes stuttering?
Büchel C, Sommer M
PLoS Biol 2004 Feb;2(2):E46. Epub 2004 Feb 17 doi: 10.1371/journal.pbio.0020046. PMID: 14966540Free PMC Article

Clinical prediction guides

Infant microbes and metabolites point to childhood neurodevelopmental disorders.
Ahrens AP, Hyötyläinen T, Petrone JR, Igelström K, George CD, Garrett TJ, Orešič M, Triplett EW, Ludvigsson J
Cell 2024 Apr 11;187(8):1853-1873.e15. Epub 2024 Apr 3 doi: 10.1016/j.cell.2024.02.035. PMID: 38574728
Stuttering associated with a pathogenic variant in the chaperone protein cyclophilin 40.
Morgan AT, Scerri TS, Vogel AP, Reid CA, Quach M, Jackson VE, McKenzie C, Burrows EL, Bennett MF, Turner SJ, Reilly S, Horton SE, Block S, Kefalianos E, Frigerio-Domingues C, Sainz E, Rigbye KA, Featherby TJ, Richards KL, Kueh A, Herold MJ, Corbett MA, Gecz J, Helbig I, Thompson-Lake DGY, Liégeois FJ, Morell RJ, Hung A, Drayna D, Scheffer IE, Wright DK, Bahlo M, Hildebrand MS
Brain 2023 Dec 1;146(12):5086-5097. doi: 10.1093/brain/awad314. PMID: 37977818Free PMC Article
Resection of Insular Glioma Through the Transfrontal Limiting Sulcus Approach.
Sun GC, Zhao K, Shu XJ, Liu RY, Dong MX, Chen XL, Xu BN
Oper Neurosurg (Hagerstown) 2022 Jun 1;22(6):400-408. Epub 2022 Apr 14 doi: 10.1227/ons.0000000000000146. PMID: 35867080
The effect of ankyloglossia and tongue-tie division on speech articulation: A systematic review.
Wang J, Yang X, Hao S, Wang Y
Int J Paediatr Dent 2022 Mar;32(2):144-156. Epub 2021 May 22 doi: 10.1111/ipd.12802. PMID: 33964037
Refining the Phenotype of Recurrent Rearrangements of Chromosome 16.
Redaelli S, Maitz S, Crosti F, Sala E, Villa N, Spaccini L, Selicorni A, Rigoldi M, Conconi D, Dalprà L, Roversi G, Bentivegna A
Int J Mol Sci 2019 Mar 4;20(5) doi: 10.3390/ijms20051095. PMID: 30836598Free PMC Article

Recent systematic reviews

The effect of ankyloglossia and tongue-tie division on speech articulation: A systematic review.
Wang J, Yang X, Hao S, Wang Y
Int J Paediatr Dent 2022 Mar;32(2):144-156. Epub 2021 May 22 doi: 10.1111/ipd.12802. PMID: 33964037
The Relationship between Feeding and Non-Nutritive Sucking Behaviours and Speech Sound Development: A Systematic Review.
Burr S, Harding S, Wren Y, Deave T
Folia Phoniatr Logop 2021;73(2):75-88. Epub 2020 Feb 10 doi: 10.1159/000505266. PMID: 32040950
Speech and language in bilateral perisylvian polymicrogyria: a systematic review.
Braden RO, Leventer RJ, Jansen A, Scheffer IE, Morgan AT
Dev Med Child Neurol 2019 Oct;61(10):1145-1152. Epub 2019 Jan 25 doi: 10.1111/dmcn.14153. PMID: 30680716
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT): Characteristics, treatment and outcome in 251 cases from the literature.
Laurent C, Capron J, Quillerou B, Thomas G, Alamowitch S, Fain O, Mekinian A
Autoimmun Rev 2016 Dec;15(12):1129-1133. Epub 2016 Sep 15 doi: 10.1016/j.autrev.2016.09.008. PMID: 27639840
Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes.
Vogel AP, Folker J, Poole ML
Cochrane Database Syst Rev 2014 Oct 28;2014(10):CD008953. doi: 10.1002/14651858.CD008953.pub2. PMID: 25348587Free PMC Article

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