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reactive attachment disorder

MedGen UID:
141906
Concept ID:
C0525043
Mental or Behavioral Dysfunction
Synonyms: Attachment Disorder, Reactive; Attachment Disorders, Reactive; Disorder, Reactive Attachment; Disorders, Reactive Attachment; Reactive Attachment Disorder; Reactive Attachment Disorders
SNOMED CT: Reactive attachment disorder (41526007)

Definition

Markedly disturbed and developmentally inappropriate social relatedness that begins before age 5 and is associated with grossly pathological child care. The child may persistently fail to initiate and respond to social interactions in a developmentally appropriate way (inhibited type) or there may be a pattern of diffuse attachments with nondiscriminate sociability (disinhibited type). (From DSM-V) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • reactive attachment disorder

Professional guidelines

PubMed

Seim AR, Jozefiak T, Wichstrøm L, Lydersen S, Kayed NS
Eur Child Adolesc Psychiatry 2022 Jan;31(1):85-98. Epub 2020 Nov 13 doi: 10.1007/s00787-020-01673-7. PMID: 33185772Free PMC Article
Zeanah CH, Gleason MM
J Child Psychol Psychiatry 2015 Mar;56(3):207-22. Epub 2014 Oct 31 doi: 10.1111/jcpp.12347. PMID: 25359236Free PMC Article
Hanson RF, Spratt EG
Child Maltreat 2000 May;5(2):137-45. doi: 10.1177/1077559500005002005. PMID: 11232086

Recent clinical studies

Etiology

Hornor G
J Pediatr Health Care 2019 Sep-Oct;33(5):612-622. doi: 10.1016/j.pedhc.2019.04.017. PMID: 31447013
McKenzie R, Dallos R
Clin Child Psychol Psychiatry 2017 Oct;22(4):632-648. Epub 2017 May 22 doi: 10.1177/1359104517707323. PMID: 28530116
von Klitzing K, Döhnert M, Kroll M, Grube M
Dtsch Arztebl Int 2015 May 25;112(21-22):375-86; quiz 386. doi: 10.3238/arztebl.2015.0375. PMID: 26149380Free PMC Article
Fearon RP, Bakermans-Kranenburg MJ, van Ijzendoorn MH, Lapsley AM, Roisman GI
Child Dev 2010 Mar-Apr;81(2):435-56. doi: 10.1111/j.1467-8624.2009.01405.x. PMID: 20438450
Hornor G
J Pediatr Health Care 2008 Jul-Aug;22(4):234-9. Epub 2008 Mar 5 doi: 10.1016/j.pedhc.2007.07.003. PMID: 18590868

Diagnosis

Engler AD, Sarpong KO, Van Horne BS, Greeley CS, Keefe RJ
Trauma Violence Abuse 2022 Jan;23(1):255-264. Epub 2020 Jul 20 doi: 10.1177/1524838020941197. PMID: 32686611
Hornor G
J Pediatr Health Care 2019 Sep-Oct;33(5):612-622. doi: 10.1016/j.pedhc.2019.04.017. PMID: 31447013
Allen B
Res Dev Disabil 2018 Jun;77:24-29. Epub 2018 Apr 5 doi: 10.1016/j.ridd.2018.03.012. PMID: 29626664
Hornor G
J Pediatr Health Care 2008 Jul-Aug;22(4):234-9. Epub 2008 Mar 5 doi: 10.1016/j.pedhc.2007.07.003. PMID: 18590868
Arrigo BA, Griffin A
Behav Sci Law 2004;22(3):375-93. doi: 10.1002/bsl.583. PMID: 15211558

Therapy

Guyon-Harris KL, Humphreys KL, Degnan K, Fox NA, Nelson CA, Zeanah CH
Attach Hum Dev 2019 Apr;21(2):95-110. Epub 2018 Jul 23 doi: 10.1080/14616734.2018.1499208. PMID: 30037301Free PMC Article
Lo CKM, Chan KL, Ip P
Trauma Violence Abuse 2019 Dec;20(5):706-719. Epub 2017 Sep 7 doi: 10.1177/1524838017730579. PMID: 29333992
Wright B, Hackney L, Hughes E, Barry M, Glaser D, Prior V, Allgar V, Marshall D, Barrow J, Kirby N, Garside M, Kaushal P, Perry A, McMillan D
PLoS One 2017;12(7):e0180858. Epub 2017 Jul 14 doi: 10.1371/journal.pone.0180858. PMID: 28708838Free PMC Article
Love L, Minnis H, O'connor S
Infant Ment Health J 2015 Jul-Aug;36(4):427-45. Epub 2015 Jun 19 doi: 10.1002/imhj.21520. PMID: 26096595
Wilson SL
J Psychosoc Nurs Ment Health Serv 2009 Aug;47(8):23-7. doi: 10.3928/02793695-20090706-04. PMID: 19681518

Prognosis

Engler AD, Sarpong KO, Van Horne BS, Greeley CS, Keefe RJ
Trauma Violence Abuse 2022 Jan;23(1):255-264. Epub 2020 Jul 20 doi: 10.1177/1524838020941197. PMID: 32686611
Seim AR, Jozefiak T, Wichstrøm L, Lydersen S, Kayed NS
Child Abuse Negl 2021 Aug;118:105141. Epub 2021 Jun 2 doi: 10.1016/j.chiabu.2021.105141. PMID: 34089987
Granqvist P, Sroufe LA, Dozier M, Hesse E, Steele M, van Ijzendoorn M, Solomon J, Schuengel C, Fearon P, Bakermans-Kranenburg M, Steele H, Cassidy J, Carlson E, Madigan S, Jacobvitz D, Foster S, Behrens K, Rifkin-Graboi A, Gribneau N, Spangler G, Ward MJ, True M, Spieker S, Reijman S, Reisz S, Tharner A, Nkara F, Goldwyn R, Sroufe J, Pederson D, Pederson D, Weigand R, Siegel D, Dazzi N, Bernard K, Fonagy P, Waters E, Toth S, Cicchetti D, Zeanah CH, Lyons-Ruth K, Main M, Duschinsky R
Attach Hum Dev 2017 Dec;19(6):534-558. Epub 2017 Jul 26 doi: 10.1080/14616734.2017.1354040. PMID: 28745146Free PMC Article
Agerup T, Lydersen S, Wallander J, Sund AM
Child Psychiatry Hum Dev 2015 Aug;46(4):632-42. doi: 10.1007/s10578-014-0506-y. PMID: 25319511
Pritchett R, Pritchett J, Marshall E, Davidson C, Minnis H
ScientificWorldJournal 2013;2013:818157. Epub 2013 Apr 18 doi: 10.1155/2013/818157. PMID: 23710150Free PMC Article

Clinical prediction guides

Engler AD, Sarpong KO, Van Horne BS, Greeley CS, Keefe RJ
Trauma Violence Abuse 2022 Jan;23(1):255-264. Epub 2020 Jul 20 doi: 10.1177/1524838020941197. PMID: 32686611
Bruce M, Young D, Turnbull S, Rooksby M, Chadwick G, Oates C, Nelson R, Young-Southward G, Haig C, Minnis H
Attach Hum Dev 2019 Apr;21(2):152-169. Epub 2018 Jul 18 doi: 10.1080/14616734.2018.1499211. PMID: 30021488
Granqvist P, Sroufe LA, Dozier M, Hesse E, Steele M, van Ijzendoorn M, Solomon J, Schuengel C, Fearon P, Bakermans-Kranenburg M, Steele H, Cassidy J, Carlson E, Madigan S, Jacobvitz D, Foster S, Behrens K, Rifkin-Graboi A, Gribneau N, Spangler G, Ward MJ, True M, Spieker S, Reijman S, Reisz S, Tharner A, Nkara F, Goldwyn R, Sroufe J, Pederson D, Pederson D, Weigand R, Siegel D, Dazzi N, Bernard K, Fonagy P, Waters E, Toth S, Cicchetti D, Zeanah CH, Lyons-Ruth K, Main M, Duschinsky R
Attach Hum Dev 2017 Dec;19(6):534-558. Epub 2017 Jul 26 doi: 10.1080/14616734.2017.1354040. PMID: 28745146Free PMC Article
Mayes SD, Calhoun SL, Waschbusch DA, Baweja R
Clin Child Psychol Psychiatry 2017 Oct;22(4):620-631. Epub 2016 Nov 28 doi: 10.1177/1359104516678039. PMID: 27895198
Fearon RP, Bakermans-Kranenburg MJ, van Ijzendoorn MH, Lapsley AM, Roisman GI
Child Dev 2010 Mar-Apr;81(2):435-56. doi: 10.1111/j.1467-8624.2009.01405.x. PMID: 20438450

Recent systematic reviews

Engler AD, Sarpong KO, Van Horne BS, Greeley CS, Keefe RJ
Trauma Violence Abuse 2022 Jan;23(1):255-264. Epub 2020 Jul 20 doi: 10.1177/1524838020941197. PMID: 32686611
Vasileva M, Petermann F
Trauma Violence Abuse 2018 Oct;19(4):443-458. Epub 2016 Sep 22 doi: 10.1177/1524838016669503. PMID: 27663993
Wright B, Hackney L, Hughes E, Barry M, Glaser D, Prior V, Allgar V, Marshall D, Barrow J, Kirby N, Garside M, Kaushal P, Perry A, McMillan D
PLoS One 2017;12(7):e0180858. Epub 2017 Jul 14 doi: 10.1371/journal.pone.0180858. PMID: 28708838Free PMC Article
Wright B, Barry M, Hughes E, Trépel D, Ali S, Allgar V, Cottrill L, Duffy S, Fell J, Glanville J, Glaser D, Hackney L, Manea L, McMillan D, Palmer S, Prior V, Whitton C, Perry A, Gilbody S
Health Technol Assess 2015 Jul;19(52):vii-xxviii, 1-347. doi: 10.3310/hta19520. PMID: 26177494Free PMC Article
Latimer K, Wilson P, Kemp J, Thompson L, Sim F, Gillberg C, Puckering C, Minnis H
Child Care Health Dev 2012 Sep;38(5):611-28. Epub 2012 Feb 28 doi: 10.1111/j.1365-2214.2012.01366.x. PMID: 22372737

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