GFAP-negative lamina cribrosa cell response to TGF-beta1
Summary:
Analysis of glial fibrillary acidic acid (GFAP)-negative lamina cribrosa (LC) glial cell response to 10 ng/ml TGF-beta1 for 24 hours. This is a model for primary open-angle glaucoma (POAG) in which TGF-beta levels are elevated in human LC tissue.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Kirwan RP, Leonard MO, Murphy M, Clark AF et al. Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells. Glia 2005 Dec;52(4):309-24. PMID: 16078232
