GEO DataSets

(Submitter supplied) Aging is classically conceptualized as an ever-increasing trajectory of damage accumulation and loss of function, leading to increases in morbidity and mortality. However, recent in vitro studies have raised the possibility of age reversal. We characterized several models in which biological age, assessed primarily through analysis of DNA methylation, undergoes reversible changes. Pregnancy is one such example.

Organism:

Rattus norvegicus; Homo sapiens; Mus musculus

Type:

Methylation profiling by array

Platform:

GPL28271

46 Samples

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(Submitter supplied) Developed in the labs of Steve Horvath and Jason Ernst. The mammalian array platform applies to ALL mammals (humans, mouse, rat, sheep, horses, pigs, etc.). The array design is similar to the Illumina Infinium 450K array but it contains fewer up to 37492 CpGs. Additional material can be found on the Github page https://github.com/shorvath/MammalianMethylationConsortium/ A vignette on using the mammal methylation array with SeSAMe is available from https://bioconductor.org/packages/release/bioc/vignettes/sesame/inst/doc/mammal.html. more...

Organism:

Homo sapiens; Mus musculus; Rattus norvegicus

49 Series

22420 Samples

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