Similar studies for GEO DataSets (Select 1062) - GEO DataSets

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Items: 20

Select item 10621.

Squamous cell carcinoma of the oral cavity with lymph node metastasis

Expression profiling of 18 primary squamous cell carcinomas of the oral cavity with or without lymph node metastasis. Expression in lymph node metastasis also examined. Results used to identify gene expression signature in primary tumors that indicates the presence of lymph node metastasis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state, 2 tissue sets

Platform:: GPL96
Series:: GSE2280
27 Samples

Download data: CEL

DataSet

Accession:: GDS1062

ID:: 1062

Select item 2000022802.

Prediction of lymphatic metastasis from primary squamous cell carcinoma of the oral cavity

(Submitter supplied) Metastasis via the lymphatics is a major risk factor in squamous cell carcinoma of the oral cavity (OSCC). We sought to determine whether the presence of metastasis in the regional lymph node could be predicted by a gene expression signature of the primary tumor. A total of 18 OSCCs were characterized for gene expression by hybridizing RNA to Affymetrix U133A gene chips. Genes with differential expression were identified using a permutation technique and verified by quantitative RT-PCR and immunohistochemistry. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1062
Platform:: GPL96
27 Samples

Download data: CEL

Series

Accession:: GSE2280

ID:: 200002280

Select item 2000318533.

Expression data from oral squamous cell carcinoma (OSCC)-derived cell lines and normal oral keratinocytes

(Submitter supplied) Oral squamous cell carcinoma (OSCC) is a lethal disease and early death usually occurs as a result of local invasion and regional lymph node metastases. We used microarrays to identify down or upregulated genes in OSCCs compared with non-malignant controls.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4560
Platforms:: GPL96 GPL570
11 Samples

Download data: CEL, CHP

Series

Accession:: GSE31853

ID:: 200031853

Select item 45604.

Oral squamous cell carcinoma-derived cell lines

Analysis of oral squamous cell carcinoma (OSCC)-derived cell lines. OSCC is a lethal disease with early death typically occurring as a result of local invasion and regional lymph node metastases. Results provide insight the molecular mechanisms underlying OSCC.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 9 cell line sets

Platform:: GPL96
Series:: GSE31853
9 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4560

ID:: 4560

Select item 2000035245.

Association b/w gene expression profile & tumor invasion in OSCC

(Submitter supplied) There are limited studies attempting to correlate the expression changes in oral squamous cell carcinoma with clinically relevant variables. We determined the gene expression profile of 16 tumor and 4 normal tissues from 16 patients by means of Affymetrix Hu133A GeneChips. The hybridized RNA was isolated from cells obtained with laser capture microdissection, then was amplified and labeled using T7 polymerase-based in vitro transcription. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1584
Platform:: GPL96
20 Samples

Download data: CEL

Series

Accession:: GSE3524

ID:: 200003524

Select item 15846.

Oral squamous cell carcinoma

Analysis of oral squamous cell carcinoma (OSCC) cells from 16 patients. OSCC cells isolated from tumors by laser capture microdissection. Results identify a strong correlation between gene expression profile and tumor invasiveness in OSCC.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 9 other sets

Platform:: GPL96
Series:: GSE3524
20 Samples

Download data: CEL

DataSet

Accession:: GDS1584

ID:: 1584

Select item 2000307887.

Validation of an expression signature for lymph node metastasis detection in oral cavity squamous cell carcinoma

(Submitter supplied) Validation of a previously established gene expression profile for detection of lymph node metastasis (ArrayExpress E-UMCU-11).

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL13952 GPL13953
316 Samples

Download data: TXT

Series

Accession:: GSE30788

ID:: 200030788

Select item 2000156418.

Gene signatures of progression and metastasis in renal cell cancer

(Submitter supplied) In order to address the progression, metastasis, and clinical heterogeneity of renal cell cancer (RCC), transcriptional profiling with oligonucleotide microarrays (22,283 genes) was done on 49 RCC tumors, 20 non-RCC renal tumors, and 23 normal kidney samples. Samples were clustered based on gene expression profiles and specific gene sets for each renal tumor type were identified. Gene expression was correlated to disease progression and a metastasis gene signature was derived. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
92 Samples

Download data: CEL, TXT

Series

Accession:: GSE15641

ID:: 200015641

Select item 2000074109.

Gene expression in early stage cervical cancer

(Submitter supplied) Gene expression profiling of early stage cervical cancer tumours with and without lymph node metastasis, in order to predict lymph node metastasis before treatment. Subsequently, comparing gene expression profiles between healthy cervical tissue and early stage cervical cancer tissue. Keywords: Disease stage analysis

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1708
45 Samples

Download data: TXT

Series

Accession:: GSE7410

ID:: 200007410

Select item 20000445910.

Gene expression signature and the prediction of lymph node metastases

(Submitter supplied) Samples were taken from colorectal cancers in surgically resected specimens in 89 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be used for molecular markers for predicting lymph node metastases. Keywords: disease state analysis

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
89 Samples

Download data

Series

Accession:: GSE4459

ID:: 200004459

Select item 20000467611.

Gene expression profiles of oral tongue squamous cell carcinoma tissues.

(Submitter supplied) Gene expression profiles of oral tongue squamous cell carcinoma tissues. Keywords: human tongue cancer, brachytherapy, biopsy sample, primary tissues

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2891
98 Samples

Download data

Series

Accession:: GSE4676

ID:: 200004676

Select item 20000283712.

Survival Prediction of HNSCC using FFPE samples

(Submitter supplied) Recently it was shown that gene expression signatures generated from DNA microarray analyses have promise as biomarkers of clinical outcome and that the molecular characteristics of tumors could be elucidated. Through this study, we have determined a high-risk signature for recurrence as a prognostic biomarker using formalin-fixed HNSCC tumors and tested the results to an independent data set obtained from fresh frozen tumors as a comparison. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1352
40 Samples

Download data

Series

Accession:: GSE2837

ID:: 200002837

Select item 20000457313.

Gene expression signatures for predicting prognosis of squamous cell lung carcinomas

(Submitter supplied) Gene signatures were derived to separate high risk patients from low risk ones.. Keywords: prognosis analysis

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2373
Platform:: GPL96
130 Samples

Download data

Series

Accession:: GSE4573

ID:: 200004573

Select item 237314.

Squamous cell lung carcinomas

Analysis of primary squamous cell lung carcinomas (SCCs) from 129 patients. SCCs and adenocarcinomas compose the majority of non small cell lung cancers. Gene expression profiles were compared to clinical outcome.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 6 disease state, 2 gender, 12 other sets

Platform:: GPL96
Series:: GSE4573
130 Samples

Download data

DataSet

Accession:: GDS2373

ID:: 2373

Select item 20000582815.

Gene expression profiling classifies lung squamous cell carcinomas with N1 positive lymph nodes

(Submitter supplied) Using gene expression microarrays, we tested whether lung SCCs that have metastasised to loco-regional lymph nodes (N1/2m) are different to those that directly invade and involve local nodes (N1d). Using 22,323 element microarrays, a non-parametric test identified 126 genes/transcripts that discriminated between N0 (n=35) and N1/2m (n=16) tumours (Wilcoxon-Mann-Whitney U test, P<0.01). Hiearchical clustering of all 59 tumours (including 8 N1d tumours) demonstrated the N1d tumours clustered with the N0 tumours rather than the N1/2m tumours. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL3877
59 Samples

Download data

Series

Accession:: GSE5828

ID:: 200005828

Select item 20005906916.

OSCC whole genome expression by T stage

(Submitter supplied) Differentially expressed genes between T4 and T1 stage human oral squamous cell carcinoma (OSCC)

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL14550
36 Samples

Download data: TXT

Series

Accession:: GSE59069

ID:: 200059069

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20003694217.

Genomic profiling of oral squamous cell carcinoma by array-based comparative genomic hybridization

(Submitter supplied) In this study, we investigated CNAs of 40 tumor samples from 25 patients, including 15 metastatic primary tumor (MPT), paired neck lymph-node metastasis (LNM) and 10 non-metastatic primary tumor (NMPT), by 44k oligonucleotide-based array comparative genomic hybridization (array CGH).

Organism:: Homo sapiens

Type:: Genome variation profiling by array

Platform:: GPL5477
42 Samples

Download data: TXT

Series

Accession:: GSE36942

ID:: 200036942

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20003105618.

A gene signature in histologically normal surgical margins is predictive of oral carcinoma recurrence

(Submitter supplied) Samples were prospectively collected from patients with histologically normal surgical resection margins. 96 tissue samples (histologically normal margins, oral carcinoma and adjacent normal tissues) from 24 patients comprised the training set. Our study design was guided by the hypothesis that the expression of genes present in oral squamous cell carcinoma (OSCC) but not in healthy oral tissues would be indicative of recurrence in advance of histological alteration. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4562
Platform:: GPL10526
96 Samples

Download data: CEL

Series

Accession:: GSE31056

ID:: 200031056

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 456219.

Squamous cell carcinoma of the tongue: tumors and histologically normal surgical margins

Analysis of oral carcinoma, histologically normal margins, and adjacent normal tissues from patients with squamous cell carcinoma (OSCC) of the tongue (training set). Results provide insight into molecular signature in histologically normal margins that is predictive of oral carcinoma recurrence.