U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 6

1.

Gene expression associated with liver metabolism during viral hemorrhagic fever

(Submitter supplied) Rhesus macaques (Macaca mulatta) infected with a lethal dose of lymphocytic choriomeningitis virus-strain WE (LCMV-WE) provide a model for Lassa fever virus infection of man. Like Lassa fever in human beings, disease begins with flu-like symptoms but can progress to morbidity fairly rapidly. Previously, we profiled the blood transcriptome of LCMV-infected monkeys (M. Djavani et al. J. Virol. 2007: PMID 17522210) showing distinct pre-viremic and viremic stages that discriminated between virulent and benign infections. more...
Organism:
Macaca mulatta; Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4161
Platform:
GPL570
20 Samples
Download data: CEL
Series
Accession:
GSE12254
ID:
200012254
2.
Full record GDS4161

Nonhuman primate model of Lassa fever: liver

Temporal analysis of liver from macaques infected with virulent lymphocytic choriomeningitis virus (LCMV)-WE or with non-virulent LCMV-Armstrong. LCMV-WE-infected macaques develop viral hemorrhagic fever similar to human Lassa fever. Results provide insight into molecular basis of LCMV pathogenesis.
Organism:
Macaca mulatta; Homo sapiens
Type:
Expression profiling by array, transformed count, 3 disease state, 4 infection, 11 time sets
Platform:
GPL570
Series:
GSE12254
20 Samples
Download data: CEL
3.

Primate blood signs of arenavirus hemorrhagic fever

(Submitter supplied) Lassa fever virus is a zoonotic pathogen that plagues the endemic areas of West Africa. Rhesus macaques infected with a related arenavirus, LCMV-WE, serve as a model for Lassa-infection of human beings. Using a dose similar to that expected from a needle-stick, monkeys experience an early pre-viremic phase (day 1-3), a viremic phase with febrile onset (day 4-7), and, like human beings who succumb, they die within two weeks. more...
Organism:
Macaca mulatta; Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
24 Samples
Download data: CEL
Series
Accession:
GSE5790
ID:
200005790
4.

Transcriptional comparison of cynomolgus macaques (Macaca fascicularis) following infection with Lassa or Lujo viruses

(Submitter supplied) Microarray analysis of PBMC from cynomolgus macaques collected longitudinally over the course of infection with Lassa-Josiah, Lassa-Z132, Lassa-SorombaR, or Lujo viruses (n=3 animals/infection condition).
Organism:
Macaca fascicularis; Macaca mulatta
Type:
Expression profiling by array
Platform:
GPL14569
61 Samples
Download data: TXT
Series
Accession:
GSE49838
ID:
200049838
5.

Expression data from Rhesus immune cells responding to YFV

(Submitter supplied) Immune response to infection involves the regulation of numerouse genes in numerous cell types. The number and type of genes that become differentially expressed in response to infection can result in very different pathophysiologic presentations and disease course. Wild type YFV and 17D despite having very few genetic differences result in very different disease outcomes in human and monkey hosts. We used microarrays to detail the global programme of gene expression of Rhesus macaque immune cells responding to both wild type and 17D strains of YFV. We identified distinct classes of gene expression as well as marked differences in differential gene expression between responses to 17D and wild type strains of YFV.
Organism:
Macaca mulatta
Type:
Expression profiling by array
Platform:
GPL3535
12 Samples
Download data: CEL
Series
Accession:
GSE51972
ID:
200051972
6.

Systemic persistent RNA virus infection is short-lived at the single cell level

(Submitter supplied) We report that cells infected with the prototypic arenavirus LCMV are continiously cleared from the infection in a non-cytolytic manner. Non-cytolytic clearance of murine hepatocytes goes along with profound alterations in gene expression.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
19 Samples
Download data: TSV
Series
Accession:
GSE157431
ID:
200157431
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=1|qty=5|blobid=MCID_6751d46d929f4f59327aed7e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center