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Links from GEO DataSets

Items: 8

1.

Transcriptomic analysis of SM21 resistant and susceptible haploid Candida albicans strains

(Submitter supplied) A comprehensive RNASeq analysis was performed on the haploid parent GZY803 and strains resistant to SM21 antifungal. Results imply the mechanisms underlying resistance responses.
Organism:
Candida albicans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24129
36 Samples
Download data: TXT
Series
Accession:
GSE104900
ID:
200104900
2.

Gene expression in response to fluconazole vs. the combination of fluconazole and osthole

(Submitter supplied) Transcriptional profiling of Candida albicans comparing fluconazole treated cells with fluconazole and osthole treated cells
Organism:
Candida albicans
Type:
Expression profiling by array
Platform:
GPL9728
3 Samples
Download data: LSR
Series
Accession:
GSE84936
ID:
200084936
3.

Identification and mode of action of a plant natural product targeting human fungal pathogens

(Submitter supplied) Candida albicans was subjected to treatment with tomatidine and samples were taken at 2 different time points (1h, 3h). The results show that tomatidine induces genes involved in ergosterol biosynthesis as compared to untreated controls.
Organism:
Candida albicans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19036
12 Samples
Download data: XLSX
Series
Accession:
GSE96965
ID:
200096965
4.

RNA abundance in wild-type and rtt109 -/- Candida albicans, with and without peroxide stress

(Submitter supplied) Candida albicans is a ubiquitous opportunistic pathogen that is the most prevalent cause of hospital-acquired fungal infections. In mammalian hosts, C. albicans is engulfed by phagocytes that attack the pathogen with DNA-damaging reactive oxygen species (ROS). Acetylation of histone H3 lysine 56 (H3K56) by the fungal-specific histone acetyltransferase Rtt109 is important for yeast model organisms to survive DNA damage and maintain genome integrity. more...
Organism:
Candida albicans
Type:
Expression profiling by array
Platform:
GPL9545
8 Samples
Download data: GPR
Series
Accession:
GSE18936
ID:
200018936
5.

Candida glabrata haploid and diploid

(Submitter supplied) The different expression of Candida glabrata haploid and diploid.
Organism:
Nakaseomyces glabratus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30061
6 Samples
Download data: TXT
Series
Accession:
GSE173617
ID:
200173617
6.

Comparative Genome Hybridization between Candida albicans and Candida dubliniensis and their derivatives

(Submitter supplied) Total genomic DNAs of J118, CdUM4b, the pseudotetraploid hybrid strain HBT1 and the progeny hybrid strain HBP1 were isolated. In an attempt to determine the number of copies of individual chromosomes, we used comparative genome hybridization (CGH) analysis using specially designed whole genome microarrays representing C. albicans and C. dubliniensis genomes. The arrays contained 60 mer probes that fell in three categories either C. more...
Organism:
Candida albicans; Candida dubliniensis; Candida albicans x Candida dubliniensis
Type:
Genome variation profiling by genome tiling array
Platform:
GPL10949
4 Samples
Download data: TXT
Series
Accession:
GSE24269
ID:
200024269
7.

Combining Genome-wide Gene Expression Analysis (RNA-seq) and Gene Editing Platform (CRISPR-Cas9) to Uncover the Selectively Pro-oxidant Activity of Aurone Compound against Candida albicans

(Submitter supplied) The antifungal activity of aurones SH1009 and SH9051 against Candida albicans was investigated. A whole-genome transcriptional analysis post aurone SH1009 and SH9051 treatments on the C. albicans SC5314 strain was performed using RNA-seq technique.
Organism:
Candida albicans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL15645
9 Samples
Download data: XLSX
Series
Accession:
GSE158472
ID:
200158472
8.

Saccharomyces cerevisiae deletion collections chemogenomic screen with Triclosan, Methylparaben and Ethylzingerone

(Submitter supplied) Growth assay in the presence of a toxic chemical that uses the barcoded collections of yeast gene deletions (haploid, diploid, DamP) to identify deletion strains that are hypersensitive to the drug.
Organism:
Saccharomyces cerevisiae; Saccharomyces cerevisiae S288C
Type:
Expression profiling by array
Platform:
GPL18088
6 Samples
Download data: GPR
Series
Accession:
GSE125353
ID:
200125353
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