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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001014437.3 → NP_001014437.1 cysteine--tRNA ligase, cytoplasmic isoform c
See identical proteins and their annotated locations for NP_001014437.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) includes an additional in-frame exon in the 5' coding region, and uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (c) has an additional segment in the N-terminal region and a distinct and longer C-terminus, compared to isoform a.
- Source sequence(s)
-
BX647906
- Consensus CDS
-
CCDS41600.1
- UniProtKB/TrEMBL
-
B4DPV7
- Related
- ENSP00000369897.4, ENST00000380525.9
- Conserved Domains (3) summary
-
- cd00672
Location:113 → 528
- CysRS_core; catalytic core domain of cysteinyl tRNA synthetase
- cd10310
Location:3 → 76
- GST_C_CysRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of Cysteinyl-tRNA synthetase from higher eukaryotes
- PTZ00399
Location:91 → 822
- PTZ00399; cysteinyl-tRNA-synthetase; Provisional
-
NM_001194997.2 → NP_001181926.1 cysteine--tRNA ligase, cytoplasmic isoform e
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) includes an additional in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (e) that is longer than isoform a.
- Source sequence(s)
-
AC131971, AI432096, AK298514, DC376478
- UniProtKB/TrEMBL
-
B4DPV7
- Conserved Domains (3) summary
-
- cd00672
Location:113 → 528
- CysRS_core; catalytic core domain of cysteinyl tRNA synthetase
- cd10310
Location:3 → 76
- GST_C_CysRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of Cysteinyl-tRNA synthetase from higher eukaryotes
- PTZ00399
Location:91 → 787
- PTZ00399; cysteinyl-tRNA-synthetase; Provisional
-
NM_001378136.1 → NP_001365065.1 cysteine--tRNA ligase, cytoplasmic isoform f
Status: REVIEWED
- Source sequence(s)
-
AC108448, AC131971, AK296763
- Consensus CDS
-
CCDS91411.1
- UniProtKB/TrEMBL
- B4DKY1, E9PPK8, Q53HG6
- Related
- ENSP00000432619.2, ENST00000529772.5
- Conserved Domains (1) summary
-
- PTZ00399
Location:28 → 717
- PTZ00399; cysteinyl-tRNA-synthetase; Provisional
-
NM_001378137.1 → NP_001365066.1 cysteine--tRNA ligase, cytoplasmic isoform g
Status: REVIEWED
- Source sequence(s)
-
AC108448, AC131971
- UniProtKB/TrEMBL
- A8MVQ3, B4DI19
- Conserved Domains (1) summary
-
- PTZ00399
Location:28 → 729
- PTZ00399; cysteinyl-tRNA-synthetase; Provisional
-
NM_001378138.1 → NP_001365067.1 cysteine--tRNA ligase, cytoplasmic isoform h
Status: REVIEWED
- Source sequence(s)
-
AC108448, AC131971
- UniProtKB/TrEMBL
-
B4DI19
- Conserved Domains (1) summary
-
- PTZ00399
Location:28 → 694
- PTZ00399; cysteinyl-tRNA-synthetase; Provisional
-
NM_001378139.1 → NP_001365068.1 cysteine--tRNA ligase, cytoplasmic isoform h
Status: REVIEWED
- Source sequence(s)
-
AC108448, AC131971
- UniProtKB/TrEMBL
-
B4DI19
- Conserved Domains (1) summary
-
- PTZ00399
Location:28 → 694
- PTZ00399; cysteinyl-tRNA-synthetase; Provisional
-
NM_001378140.1 → NP_001365069.1 cysteine--tRNA ligase, cytoplasmic isoform i
Status: REVIEWED
- Source sequence(s)
-
AC108448, AC131971
- UniProtKB/TrEMBL
-
B4DI19
- Conserved Domains (1) summary
-
- PTZ00399
Location:1 → 647
- PTZ00399; cysteinyl-tRNA-synthetase; Provisional
-
NM_001751.6 → NP_001742.1 cysteine--tRNA ligase, cytoplasmic isoform b
See identical proteins and their annotated locations for NP_001742.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (b) has a longer and distinct C-terminus, compared to isoform a.
- Source sequence(s)
-
BC002880
- Consensus CDS
-
CCDS7742.1
- UniProtKB/Swiss-Prot
- P49589, Q53XI8, Q5HYE4, Q9HD24, Q9HD25
- UniProtKB/TrEMBL
-
Q53HG6
- Related
- ENSP00000380300.5, ENST00000397111.9
- Conserved Domains (1) summary
-
- PTZ00399
Location:3 → 739
- PTZ00399; cysteinyl-tRNA-synthetase; Provisional
-
NM_139273.4 → NP_644802.1 cysteine--tRNA ligase, cytoplasmic isoform a
See identical proteins and their annotated locations for NP_644802.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) consists of 22 exons and encodes the shortest isoform (a).
- Source sequence(s)
-
AF288207, AI608729, DC376478
- Consensus CDS
-
CCDS41602.1
- UniProtKB/TrEMBL
-
Q53HG6
- Related
- ENSP00000278224.9, ENST00000278224.13
- Conserved Domains (2) summary
-
- cd00672
Location:30 → 445
- CysRS_core; catalytic core domain of cysteinyl tRNA synthetase
- PTZ00399
Location:3 → 704
- PTZ00399; cysteinyl-tRNA-synthetase; Provisional
RNA
-
NR_036542.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) includes an additional exon in the 5' region, and uses an alternate splice site in both the 5' and 3' regions, compared to variant 1. This variant is represented as non-coding because the use of the supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC108448, AI432096, AK096313, DC376478
- Related
-
ENST00000531387.5
-
NR_165428.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC108448, AC131971
-
NR_165429.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC108448, AC131971
-
NR_165430.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC108448, AC131971
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000011.10 Reference GRCh38.p14 Primary Assembly
- Range
-
3000929..3057423 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047427673.1 → XP_047283629.1 cysteine--tRNA ligase, cytoplasmic isoform X2
- UniProtKB/TrEMBL
-
A8K067
-
XM_047427672.1 → XP_047283628.1 cysteine--tRNA ligase, cytoplasmic isoform X1
- UniProtKB/TrEMBL
-
B4DPV7
-
XM_047427674.1 → XP_047283630.1 cysteine--tRNA ligase, cytoplasmic isoform X3
Reference GRCh38.p14 ALT_REF_LOCI_1
Genomic
-
NT_187585.1 Reference GRCh38.p14 ALT_REF_LOCI_1
- Range
-
231991..288455 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054328872.1 → XP_054184847.1 cysteine--tRNA ligase, cytoplasmic isoform X1
- UniProtKB/TrEMBL
-
B4DPV7
-
XM_054328873.1 → XP_054184848.1 cysteine--tRNA ligase, cytoplasmic isoform X3
Alternate T2T-CHM13v2.0
Genomic
-
NC_060935.1 Alternate T2T-CHM13v2.0
- Range
-
3090162..3146645 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054370125.1 → XP_054226100.1 cysteine--tRNA ligase, cytoplasmic isoform X2
- UniProtKB/TrEMBL
-
A8K067
-
XM_054370124.1 → XP_054226099.1 cysteine--tRNA ligase, cytoplasmic isoform X1
- UniProtKB/TrEMBL
-
B4DPV7
-
XM_054370126.1 → XP_054226101.1 cysteine--tRNA ligase, cytoplasmic isoform X3
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001014438.1: Suppressed sequence
- Description
- NM_001014438.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.