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Status |
Public on Mar 14, 2009 |
Title |
Vastus lateralis muscle of patients with an acute COPD exacerbation |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
To further unravel the potential molecular mechanisms involved in the loss of muscle function during an acute exacerbation, a cross-sectional microarray study was designed to compare the gene expression profile of the vastus lateralis muscle in patients with an acute COPD exacerbation and in stable COPD patients. Keywords: cross-sectional patient study
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Overall design |
A cross-sectional microarray study was designed. The microarray screening was performed on a vastus lateralis biopsy obtained from 4 patients with an acute COPD exacerbation and 5 stable COPD patients. No replicates or dye-swaps were included.
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Contributor(s) |
Crul T, Testelmans D, Spruit MA, Gayan-Ramirez G, Troosters T, Gosselink R, Geeraerts I, Decramer M |
Citation(s) |
20332630 |
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Submission date |
Mar 14, 2008 |
Last update date |
Apr 29, 2019 |
Contact name |
Tim Crul |
Organization name |
University of Leuven
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Department |
Pathophysiology
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Lab |
Pneumology
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Street address |
Herestraat 49 - 706
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City |
Leuven |
ZIP/Postal code |
3000 |
Country |
Belgium |
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Platforms (1) |
GPL2891 |
GE Healthcare/Amersham Biosciences CodeLinkā¢ UniSet Human 20K I Bioarray |
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Samples (9)
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GSM273723 |
T00252617 vastus lateralis COPD exacerbation |
GSM273724 |
T00252619 vastus lateralis COPD exacerbation |
GSM273726 |
T00252621 vastus lateralis COPD exacerbation |
GSM273728 |
T00251332 vastus lateralis COPD exacerbation |
GSM274172 |
T00252618 Vastus lateralis stable COPD |
GSM274173 |
T00252620 vastus lateralis stable COPD |
GSM274174 |
T00252622 Vastus lateralis stable COPD |
GSM274175 |
T00251333 vastus lateralis stable COPD |
GSM274177 |
T00251335 vastus lateralis stable COPD |
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Relations |
BioProject |
PRJNA107433 |