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Series GSE127787 Query DataSets for GSE127787
Status Public on Mar 01, 2020
Title 17β-estradiol regulates the release of exosomes via miR-1495p and hnRNPA2/B1 in ER+ breast cancer cells
Platform organism synthetic construct
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary We analyzed RNA from 2 breast cancer cell lines (MDA-MB-231 (MM231) and MCF7) and exosomes derived from them
We used Affymetrix miRNA-3 array to determine the miRNA profile to find out whether miRs content in exosomes and expression levels were different after 17β-estradiol .
 
Overall design Here, we performed a global profiling of differentially expressed miRNAs in breast cancer cell lines
 
Contributor(s) Pardini B, Calin GA
Citation(s) 37252969
Submission date Mar 04, 2019
Last update date May 31, 2023
Contact name George Calin
E-mail(s) gcalin@mdanderson.org
Phone 713-792-5461
Organization name MD Anderson Cancer Center
Department Experimental Therapeutics
Street address 1881 East Road
City Houston
State/province TX
ZIP/Postal code 77054
Country USA
 
Platforms (1)
GPL16384 [miRNA-3] Affymetrix Multispecies miRNA-3 Array
Samples (16)
GSM3638704 RNA from MCF7 cells treated with 17β-estradiol replicate 1
GSM3638705 RNA from MCF7 cells treated with 17β-estradiol replicate 2
GSM3638706 RNA from MCF7 cells not treated with 17β-estradiol replicate 1
Relations
BioProject PRJNA525398

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE127787_RAW.tar 36.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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