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| Status |
Public on Feb 14, 2009 |
| Title |
Expression data from rhabdomyosarcoma cells expressing Myod and E-protein heterodimer and controls |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Rhabdomyosarcomas (RMS) are characterized by expression of myogenic specification genes, such as MyoD and/or Myf5, as well as their bHLH partners for heterodimerization, the E-proteins. We have shown that expression of a forced heterodimer of MyoD with one of the E2A proteins, E12, leads to differentiation in a RMS cell culture model when exposed to low serum conditions.
Keywords: RD expressing Myod~E heterodimers and controls
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| Overall design |
RD cells (a type of RMS) were retrovirally infected with either the MyoD~E heterodimer or an empty control vector, differentiated for 24 hours and then RNA collected.
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| Contributor(s) |
Yang Z, MacQuarrie K, Analau E, Dilworth FJ, Cao Y, Diede SJ, Tapscott SJ |
| Citation(s) |
19299559 |
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| Submission date |
Feb 13, 2009 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Yi Cao |
| E-mail(s) |
ycao@fhcrc.org
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| Phone |
206-667-5278
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| Organization name |
Fred Hutchinson CRC
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| Department |
Human Biology
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| Lab |
Tapscott
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| Street address |
1100 Fairview Ave. N
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| City |
Seatttle |
| State/province |
WA |
| ZIP/Postal code |
98109 |
| Country |
USA |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA112059 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE14825_RAW.tar |
30.3 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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