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Series GSE174767 Query DataSets for GSE174767
Status Public on Nov 25, 2021
Title Methylation studies in horses
Platform organisms Homo sapiens; Mus musculus; Rattus norvegicus
Sample organism Equus caballus
Experiment type Methylation profiling by array
Summary An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from many tissues from horses
We generated DNA methylation data from n=333 horse tissue samples representing tissues. Blood samples were collected via venipuncture into EDTA tubes from across 24 different horse breeds (buffy coat). The other tissues were collected at necropsy. The tissue atlas was generated from two Thoroughbred mares as part of the FAANG initiative 37, with the following tissues profiled: adipose (gluteal), adrenal cortex, blood (PBMCs; only n=1 mare), cartilage (only n=1 mare), cecum, cerebellum (2 samples each from lateral hemisphere and vermis), frontal cortex, duodenum, fibroblast, heart (2 samples each from the right atrium, left atrium, right ventricle, left ventricle), hypothalamus, ileum, jejunum, keratinocyte, kidney (kidney cortex and medulla), lamina, larynx (i.e. cricoarytenoideus dorsalis muscle), liver, lung, mammary gland, mitral valve of the heart, skeletal muscle (gluteal muscle and longissimus muscle), occipital cortex, ovary, parietal cortex, pituitary, sacrocaudalis dorsalis muscle, skin, spinal cord (C1 and T8), spleen, suspensory ligament, temporal cortex, tendon (deep digital flexor tendon and superficial digital flexor tendon), uterus.
 
Overall design N=333 tissue samples from horses. Genome annotations of the array can be downloaded from https://github.com/shorvath/MammalianMethylationConsortium
 
Contributor(s) Horvath S, Finno C
Citation(s) 35013267, 35145108, 37563227, 38848365
Submission date May 20, 2021
Last update date Jun 26, 2024
Contact name Steve Horvath
E-mail(s) shorvath@altoslabs.com
Organization name University of California, Los Angeles
Department Human Genetics
Lab Horvath
Street address 695 Charles E. Young Drive South, Box 708822
City Los Angeles
State/province CA
ZIP/Postal code 90095-7088
Country USA
 
Platforms (1)
GPL28271 Illumina HorvathMammalianMethylChip40 BeadChip
Samples (333)
GSM5326958 Sample1.Horse.203203210051_R01C01
GSM5326959 Sample2.Horse.203203210051_R02C01
GSM5326960 Sample3.Horse.203203210051_R03C01
Relations
BioProject PRJNA731494

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE174767_Explanation_of_characteristic_variables.txt.gz 219 b (ftp)(http) TXT
GSE174767_RAW.tar 249.7 Mb (http)(custom) TAR (of IDAT)
Processed data included within Sample table

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