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| Status |
Public on May 05, 2022 |
| Title |
Full-length transcriptome sequencing reveals gene expression signatures in human soft tissue sarcomas |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Soft tissue sarcomas (STSs) are heterogeneous malignancies derived from mesenchymal cells. Due to its rarity, heterogeneity, and limited overall response to chemotherapy, STSs represents a therapeutic challenge. Necroptosis is a novel therapeutic strategy for enhancing immunotherapy of cancer. Nevertheless, no research has explored the relationship between necroptosis-related genes (NRGs) and STSs.We performed full-length transcriptome analysis of four pairs of soft-tissue sarcomas and normal normal adjacent tissues. We further validated the expression level of necroptosis-related genes (NRGs) in these sample pairs.
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| Overall design |
We performed full-length transcriptome analysis of four pairs of soft-tissue sarcomas and normal normal adjacent tissues. We further validated the expression level of necroptosis-related genes (NRGs) in these sample pairs.
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| Contributor(s) |
Li Z, Tu C, Qi L |
| Citation(s) |
35860263, 36937870 |
| |
| Submission date |
Mar 14, 2022 |
| Last update date |
Jul 14, 2023 |
| Contact name |
Lin Qi |
| Organization name |
The Second Xiangya Hospital, Central South University
|
| Street address |
139 Renmin Road
|
| City |
Changsha |
| ZIP/Postal code |
410011 |
| Country |
China |
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| Platforms (1) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA816053 |
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