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| Status |
Public on Jan 12, 2012 |
| Title |
Estrogen receptors in breast cancer stem cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Breast cancer stem cells are considered estrogen receptor negative and estrogen insensitive. However, estrogens potentiate growth of the vast majority of breast tumors. In this study, we characterize the expression of estrogen receptors in breast cancer stem cells.
We used microarrays to characterize the global gene expression underlying estrogen receptor activation versus inhibition in breast cancer cells from invasive breast cancers.
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| Overall design |
Cancer cells from invasive breast carcinomas are treated with D (DPN), T (4OHT) or untreated (vehicle control).
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| Contributor(s) |
Hartman J, Lindström L |
| Citation(s) |
26208432 |
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| Submission date |
Jan 11, 2012 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Johan Hartman |
| E-mail(s) |
johan.hartman@ki.se
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| Organization name |
Karolinska Institute
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| Department |
Dept of Oncology and Pathology
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| Street address |
R8:03, CCK
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| City |
Stockholm |
| ZIP/Postal code |
SE-171 77 |
| Country |
Sweden |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (24)
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| GSM861015 |
individual 33, untreated |
| GSM861016 |
individual 33, D treatment |
| GSM861017 |
individual 33, T treatment |
| GSM861018 |
individual 35, untreated |
| GSM861019 |
individual 35, D treatment |
| GSM861020 |
individual 35, T treatment |
| GSM861021 |
individual 41, untreated |
| GSM861022 |
individual 41, D treatment |
| GSM861023 |
individual 41, T treatment |
| GSM861024 |
individual 57, untreated |
| GSM861025 |
individual 57, D treatment |
| GSM861026 |
individual 57, T treatment |
| GSM861027 |
individual 69, untreated |
| GSM861028 |
individual 69, D treatment |
| GSM861029 |
individual 69, T treatment |
| GSM861030 |
individual 84, untreated |
| GSM861031 |
individual 84, D treatment |
| GSM861032 |
individual 84, T treatment |
| GSM861033 |
individual 92, untreated |
| GSM861034 |
individual 92, D treatment |
| GSM861035 |
individual 92, T treatment |
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| Relations |
| BioProject |
PRJNA150863 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE35031_RAW.tar |
89.1 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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