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Pyriform Fossa Neoplasm

MedGen UID:
138025
•Concept ID:
C0345704
•
Neoplastic Process
Synonyms: Neoplasm of Pyriform Fossa; Neoplasm of pyriform sinus; Neoplasm of Pyriform Sinus; Neoplasm of the Pyriform Fossa; Neoplasm of the Pyriform Sinus; Pyriform Fossa Tumor; Pyriform Sinus Neoplasm; Pyriform Sinus Tumor; Tumor of pyriform fossa; Tumor of Pyriform Fossa; Tumor of Pyriform Sinus; Tumor of the Pyriform Fossa; Tumor of the Pyriform Sinus
SNOMED CT: Neoplasm of pyriform sinus (126688006); Tumor of pyriform fossa (126688006)

Definition

A benign or malignant neoplasm that affects the pyriform sinus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPyriform Fossa Neoplasm

Professional guidelines

PubMed

Integrated cone-beam CT and fluoroscopic navigation in treatment of head and neck vascular malformations and tumors.
Nesbit GM, Nesbit EG, Hamilton BE
J Neurointerv Surg 2011 Jun;3(2):186-90. Epub 2010 Dec 16 doi: 10.1136/jnis.2010.003376. PMID: 21990816
Hypopharyngeal cancer: results of treatment based on radiation therapy and salvage surgery.
Godballe C, Jørgensen K, Hansen O, Bastholt L
Laryngoscope 2002 May;112(5):834-8. doi: 10.1097/00005537-200205000-00011. PMID: 12150614
Treatment and long-term outcome of chronic radiation esophagitis after radiation therapy for head and neck tumors. A report of 13 cases.
Silvain C, Barrioz T, Besson I, Babin P, Fontanel JP, Daban A, Matuchansky C, Beauchant M
Dig Dis Sci 1993 May;38(5):927-31. doi: 10.1007/BF01295922. PMID: 8482193

Recent clinical studies

Etiology

Swallowing in advanced oral cancers: A prospective observational study.
Malik A, Sharin F, Balaji A, Mathur Y, Nair S, Chaturvedi P, Nair D
J Cancer Res Ther 2024 Jan 1;20(1):340-348. Epub 2024 Mar 29 doi: 10.4103/jcrt.jcrt_1499_22. PMID: 38554344
Hypopharyngeal spindle cell lipoma: A case report and review of literature.
Liang Z, Zang Y, Jing Z, Zhang Y, Cao H, Zhou H
Medicine (Baltimore) 2021 May 7;100(18):e25782. doi: 10.1097/MD.0000000000025782. PMID: 33950973Free PMC Article
Hypopharynx and larynx defect repair after resection for pyriform fossa cancer with a platysma skin flap.
Cai Q, Liang F, Huang X, Han P, Pan Y, Zheng Y
Otolaryngol Head Neck Surg 2015 Feb;152(2):374-6. Epub 2014 Nov 26 doi: 10.1177/0194599814559508. PMID: 25428776
Deep neck infections of congenital causes.
Nour YA, Hassan MH, Gaafar A, Eldaly A
Otolaryngol Head Neck Surg 2011 Mar;144(3):365-71. Epub 2010 Dec 20 doi: 10.1177/0194599810391629. PMID: 21493197
Near-total laryngectomy.
Pradhan SA, D'Cruz AK, Pai PS
Asian J Surg 2002 Jan;25(1):27-34. PMID: 17585442

Diagnosis

Long-Term Survival of Patients After Total Pharyngolaryngoesophagectomy With Gastric Pull-Up Reconstruction for Hypopharyngeal or Laryngeal Cancer Invading Cervical Esophagus.
Bich TA, Vuong NL, Cam Tu NCHTN, Truong TM, Trung LV
Ann Otol Rhinol Laryngol 2023 May;132(5):511-518. Epub 2022 Jun 3 doi: 10.1177/00034894221098802. PMID: 35656819
Hypopharyngeal spindle cell lipoma: A case report and review of literature.
Liang Z, Zang Y, Jing Z, Zhang Y, Cao H, Zhou H
Medicine (Baltimore) 2021 May 7;100(18):e25782. doi: 10.1097/MD.0000000000025782. PMID: 33950973Free PMC Article
Monophasic synovial sarcoma of the pyriform fossa.
Ng CT, Wong EHC, Prepageran N
BMJ Case Rep 2020 Nov 30;13(11) doi: 10.1136/bcr-2020-236204. PMID: 33257363Free PMC Article
Deep neck infections of congenital causes.
Nour YA, Hassan MH, Gaafar A, Eldaly A
Otolaryngol Head Neck Surg 2011 Mar;144(3):365-71. Epub 2010 Dec 20 doi: 10.1177/0194599810391629. PMID: 21493197
Cartilaginous tumors of the trachea and larynx.
Neis PR, McMahon MF, Norris CW
Ann Otol Rhinol Laryngol 1989 Jan;98(1 Pt 1):31-6. doi: 10.1177/000348948909800107. PMID: 2642679

Therapy

Emergency Laryngectomy Feasibility and Indications Beyond Airway Obstruction in the Era of Concurrent Chemoradiotherapy.
Battoo AJ, Sheikh ZA, Thankappan K, Haji AG
Ear Nose Throat J 2021 Dec;100(10_suppl):892S-896S. Epub 2020 May 26 doi: 10.1177/0145561320927946. PMID: 32453642
Excision versus trichloroacetic acid (TCA) chemocauterization for branchial sinus of the pyriform fossa.
Hwang J, Kim SC, Kim DY, Namgoong JM, Nam SY, Roh JL
J Pediatr Surg 2015 Nov;50(11):1949-53. Epub 2015 Jul 14 doi: 10.1016/j.jpedsurg.2015.07.006. PMID: 26282101
Pitfalls in the surgical management of cancer of the larynx and hypopharynx.
Thabet MH, Talaat M, Rizk AM
Otolaryngol Head Neck Surg 2000 Oct;123(4):482-7. doi: 10.1067/mhn.2000.105062. PMID: 11020190
Cancer of the pyriform fossa: hyperfractionated radiotherapy as a primary treatment modality.
Conlon BJ, Walsh M, McShane D, Corcoran N, Moriarty M, Healy JB, Fraser I, O'Dwyer TP
Clin Otolaryngol Allied Sci 1997 Aug;22(4):327-31. doi: 10.1046/j.1365-2273.1997.00016.x. PMID: 9298607
Complications following surgery for cancer of the larynx and pyriform fossa.
Sarkar S, Mehta SA, Tiwari J, Mehta AR, Mehta MS
J Surg Oncol 1990 Apr;43(4):245-9. doi: 10.1002/jso.2930430411. PMID: 2325423

Prognosis

Swallowing in advanced oral cancers: A prospective observational study.
Malik A, Sharin F, Balaji A, Mathur Y, Nair S, Chaturvedi P, Nair D
J Cancer Res Ther 2024 Jan 1;20(1):340-348. Epub 2024 Mar 29 doi: 10.4103/jcrt.jcrt_1499_22. PMID: 38554344
Long-Term Survival of Patients After Total Pharyngolaryngoesophagectomy With Gastric Pull-Up Reconstruction for Hypopharyngeal or Laryngeal Cancer Invading Cervical Esophagus.
Bich TA, Vuong NL, Cam Tu NCHTN, Truong TM, Trung LV
Ann Otol Rhinol Laryngol 2023 May;132(5):511-518. Epub 2022 Jun 3 doi: 10.1177/00034894221098802. PMID: 35656819
Early detection of isolated pleural metastasis from carcinoma pyriform fossa: Can it be steered away from doom?
Vashistha B, Garg P, Negi P, Kingsley PA
J Cancer Res Ther 2022 Jan-Mar;18(1):280-281. doi: 10.4103/jcrt.JCRT_1739_20. PMID: 35381801
Near-total laryngectomy.
Pradhan SA, D'Cruz AK, Pai PS
Asian J Surg 2002 Jan;25(1):27-34. PMID: 17585442
Supraglottic cancer.
Bocca E
Laryngoscope 1975 Aug;85(8):1318-26. doi: 10.1288/00005537-197508000-00007. PMID: 1160463

Clinical prediction guides

Swallowing in advanced oral cancers: A prospective observational study.
Malik A, Sharin F, Balaji A, Mathur Y, Nair S, Chaturvedi P, Nair D
J Cancer Res Ther 2024 Jan 1;20(1):340-348. Epub 2024 Mar 29 doi: 10.4103/jcrt.jcrt_1499_22. PMID: 38554344
Surgical approach of laryngofissure combined with epiglottis valley in treating locally-advanced pyriform sinus carcinoma.
Wu P, Tang Y, Fang X, Zhao S
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2021 Aug 28;46(8):843-850. doi: 10.11817/j.issn.1672-7347.2021.200996. PMID: 34565728Free PMC Article
Hypopharynx and larynx defect repair after resection for pyriform fossa cancer with a platysma skin flap.
Cai Q, Liang F, Huang X, Han P, Pan Y, Zheng Y
Otolaryngol Head Neck Surg 2015 Feb;152(2):374-6. Epub 2014 Nov 26 doi: 10.1177/0194599814559508. PMID: 25428776
Laryngopharyngeal sensory deficits and impaired pharyngeal motor function predict aspiration in patients irradiated for nasopharyngeal carcinoma.
Ku PK, Vlantis AC, Leung SF, Lee KY, Cheung DM, Abdullah VJ, van Hasselt A, Tong MC
Laryngoscope 2010 Feb;120(2):223-8. doi: 10.1002/lary.20701. PMID: 19950372
Hypopharyngeal cancer: results of treatment based on radiation therapy and salvage surgery.
Godballe C, Jørgensen K, Hansen O, Bastholt L
Laryngoscope 2002 May;112(5):834-8. doi: 10.1097/00005537-200205000-00011. PMID: 12150614

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