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Lung Soft Tissue Neoplasm

MedGen UID:
353872
•Concept ID:
C1708783
•
Neoplastic Process

Definition

A benign, intermediate, or malignant mesenchymal neoplasm that arises from the lung. [from NCI]

Professional guidelines

PubMed

Risk of second primary cancers after a diagnosis of first primary cancer: A pan-cancer analysis and Mendelian randomization study.
Ruan X, Huang D, Zhan Y, Huang J, Huang J, Ng AT, Tsu JH, Na R
Elife 2023 Nov 2;12 doi: 10.7554/eLife.86379. PMID: 37917154Free PMC Article
Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China.
Xu C, Si L, Wang W, Li Z, Song Z, Wang Q, Liu A, Yu J, Fang W, Zhong W, Wang Z, Zhang Y, Liu J, Zhang S, Cai X, Liu A, Li W, Zhan P, Liu H, Lv T, Miao L, Min L, Chen Y, Yuan J, Wang F, Jiang Z, Lin G, Pu X, Lin R, Liu W, Rao C, Lv D, Yu Z, Lei L, Li X, Tang C, Zhou C, Zhang J, Xue J, Guo H, Chu Q, Meng R, Wu J, Zhang R, Hu X, Zhou J, Zhu Z, Li Y, Qiu H, Xia F, Lu Y, Chen X, Ge R, Dai E, Han Y, Pan W, Luo J, Jia H, Dong X, Pang F, Wang K, Wang L, Zhu Y, Xie Y, Lin X, Cai J, Wei J, Lan F, Feng H, Wang L, Du Y, Yao W, Shi X, Niu X, Yuan D, Yao Y, Huang J, Zhang Y, Sun P, Wang H, Ye M, Wang D, Wang Z, Wan B, Lv D, Wei Q, Kang J, Zhang J, Zhang C, Yu G, Ou J, Shi L, Li Z, Liu Z, Liu J, Yang N, Wu L, Wang H, Jin G, Yang L, Wang G, Fang M, Fang Y, Li Y, Wang X, Zhang Y, Ma S, Wang B, Zhang X, Song Y, Lu Y
Thorac Cancer 2022 Nov;13(21):3084-3097. Epub 2022 Sep 20 doi: 10.1111/1759-7714.14644. PMID: 36127731Free PMC Article
DLL3 as an Emerging Target for the Treatment of Neuroendocrine Neoplasms.
Yao J, Bergsland E, Aggarwal R, Aparicio A, Beltran H, Crabtree JS, Hann CL, Ibrahim T, Byers LA, Sasano H, Umejiego J, Pavel M
Oncologist 2022 Nov 3;27(11):940-951. doi: 10.1093/oncolo/oyac161. PMID: 35983951Free PMC Article

Recent clinical studies

Etiology

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
CIC-DUX4 sarcomas.
Brahmi M, Vanacker H, Macagno N, Tirode F, Dufresne A
Curr Opin Oncol 2022 Jul 1;34(4):342-347. Epub 2022 Jun 22 doi: 10.1097/CCO.0000000000000855. PMID: 35730520
Primary Soft Tissue Hydatid Cysts.
Patmano M, Çetin DA, Gümüş T, Patmano G, Yenigül AE
Turkiye Parazitol Derg 2022 May 23;46(2):145-149. doi: 10.4274/tpd.galenos.2021.03511. PMID: 35604194
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Antonescu CR, Agaram NP, Sung YS, Zhang L, Swanson D, Dickson BC
Am J Surg Pathol 2018 Apr;42(4):553-560. doi: 10.1097/PAS.0000000000001010. PMID: 29309307Free PMC Article
Soft tissue limb and trunk sarcomas: diagnosis, treatment and follow-up.
Rastrelli M, Tropea S, Basso U, Roma A, Maruzzo M, Rossi CR
Anticancer Res 2014 Oct;34(10):5251-62. PMID: 25275017

Diagnosis

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
GLI1 Immunohistochemistry Distinguishes Mesenchymal Neoplasms With GLI1 Alterations From Morphologic Mimics.
Parrack PH, Mariño-Enríquez A, Fletcher CDM, Hornick JL, Papke DJ Jr
Am J Surg Pathol 2023 Apr 1;47(4):453-460. Epub 2023 Jan 23 doi: 10.1097/PAS.0000000000002018. PMID: 36693363
Basic Knowledge in Soft Tissue Sarcoma.
Bourcier K, Le Cesne A, Tselikas L, Adam J, Mir O, Honore C, de Baere T
Cardiovasc Intervent Radiol 2019 Sep;42(9):1255-1261. Epub 2019 Jun 24 doi: 10.1007/s00270-019-02259-w. PMID: 31236647
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Antonescu CR, Agaram NP, Sung YS, Zhang L, Swanson D, Dickson BC
Am J Surg Pathol 2018 Apr;42(4):553-560. doi: 10.1097/PAS.0000000000001010. PMID: 29309307Free PMC Article
Liposarcoma.
Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

Therapy

Role of Nectin‑4 protein in cancer (Review).
Liu Y, Han X, Li L, Zhang Y, Huang X, Li G, Xu C, Yin M, Zhou P, Shi F, Liu X, Zhang Y, Wang G
Int J Oncol 2021 Nov;59(5) Epub 2021 Oct 19 doi: 10.3892/ijo.2021.5273. PMID: 34664682
Talazoparib monotherapy in metastatic castration-resistant prostate cancer with DNA repair alterations (TALAPRO-1): an open-label, phase 2 trial.
de Bono JS, Mehra N, Scagliotti GV, Castro E, Dorff T, Stirling A, Stenzl A, Fleming MT, Higano CS, Saad F, Buttigliero C, van Oort IM, Laird AD, Mata M, Chen HC, Healy CG, Czibere A, Fizazi K
Lancet Oncol 2021 Sep;22(9):1250-1264. Epub 2021 Aug 10 doi: 10.1016/S1470-2045(21)00376-4. PMID: 34388386
Eribulin in Cancer Treatment.
Swami U, Shah U, Goel S
Mar Drugs 2015 Aug 7;13(8):5016-58. doi: 10.3390/md13085016. PMID: 26262627Free PMC Article
Ridaforolimus.
Drugs R D 2010;10(3):165-78. doi: 10.2165/11586010-000000000-00000. PMID: 20945947Free PMC Article
Liposarcoma.
Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

Prognosis

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
Primary pulmonary angiosarcoma.
Rana MK, Rahman O, O'Brien A
BMJ Case Rep 2021 Nov 9;14(11) doi: 10.1136/bcr-2021-244578. PMID: 34753722Free PMC Article
Basic Knowledge in Soft Tissue Sarcoma.
Bourcier K, Le Cesne A, Tselikas L, Adam J, Mir O, Honore C, de Baere T
Cardiovasc Intervent Radiol 2019 Sep;42(9):1255-1261. Epub 2019 Jun 24 doi: 10.1007/s00270-019-02259-w. PMID: 31236647
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Antonescu CR, Agaram NP, Sung YS, Zhang L, Swanson D, Dickson BC
Am J Surg Pathol 2018 Apr;42(4):553-560. doi: 10.1097/PAS.0000000000001010. PMID: 29309307Free PMC Article
Liposarcoma.
Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

Clinical prediction guides

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
Musculoskeletal Metastasis From Soft-tissue Sarcomas: A Review of the Literature.
Pretell-Mazzini J, Seldon CS, D'Amato G, Subhawong TK
J Am Acad Orthop Surg 2022 Jun 1;30(11):493-503. Epub 2022 Mar 22 doi: 10.5435/JAAOS-D-21-00944. PMID: 35320120
Metastatic pediatric sclerosing epithelioid fibrosarcoma.
Woods AD, Purohit R, Mitchell LC, Collier JR, Collier KA, Lathara M, Learned K, Vaske O, Geiger H, Wrzeszczynski KO, Jobanputra V, Srinivasa G, Rudzinski ER, Whelan K, Beierle E, Spunt SL, Keller C, Wadhwa A
Cold Spring Harb Mol Case Stud 2021 Oct;7(5) Epub 2021 Oct 19 doi: 10.1101/mcs.a006093. PMID: 34362827Free PMC Article
BCOR-CCNB3 Fusion Positive Sarcomas: A Clinicopathologic and Molecular Analysis of 36 Cases With Comparison to Morphologic Spectrum and Clinical Behavior of Other Round Cell Sarcomas.
Kao YC, Owosho AA, Sung YS, Zhang L, Fujisawa Y, Lee JC, Wexler L, Argani P, Swanson D, Dickson BC, Fletcher CDM, Antonescu CR
Am J Surg Pathol 2018 May;42(5):604-615. doi: 10.1097/PAS.0000000000000965. PMID: 29300189Free PMC Article
Metallothioneins and cancer.
Eckschlager T, Adam V, Hrabeta J, Figova K, Kizek R
Curr Protein Pept Sci 2009 Aug;10(4):360-75. doi: 10.2174/138920309788922243. PMID: 19689357

Recent systematic reviews

Clinical outcomes of brain metastasectomy from soft tissue and bone sarcomas: a systematic review.
Wang Y, Delisle M, Smith D, Alshamsan B, Srikanthan A
Int J Clin Oncol 2022 Nov;27(11):1767-1779. Epub 2022 Aug 22 doi: 10.1007/s10147-022-02227-4. PMID: 35994183
Metastasis to the oral and maxillofacial region. A systematic review.
Labrador AJP, Marin NRG, Valdez LHM, Sanchez KBT, Zabarburu W, Ibazetta KAR, Garcia AER, Cabezas DM, Romero L, Conte AM, Wright JM
J Stomatol Oral Maxillofac Surg 2022 Oct;123(5):e474-e483. Epub 2021 Dec 20 doi: 10.1016/j.jormas.2021.12.009. PMID: 34933137
A systematic review and meta-analysis of outcomes after acute limb ischemia in patients with cancer.
Govsyeyev N, Malgor RD, Hoffman C, Harroun N, Sturman E, Al-Musawi M, Malgor EA, Jacobs DL, Nehler M
J Vasc Surg 2021 Sep;74(3):1033-1040.e1. Epub 2021 Apr 24 doi: 10.1016/j.jvs.2021.03.058. PMID: 33905869
High frequency of lobular breast cancer in distant metastases to the orbit.
Raap M, Antonopoulos W, Dämmrich M, Christgen H, Steinmann D, Länger F, Lehmann U, Kreipe H, Christgen M
Cancer Med 2015 Jan;4(1):104-11. Epub 2014 Oct 30 doi: 10.1002/cam4.331. PMID: 25355547Free PMC Article
Risk of gastrointestinal events with sorafenib, sunitinib and pazopanib in patients with solid tumors: a systematic review and meta-analysis of clinical trials.
Santoni M, Conti A, De Giorgi U, Iacovelli R, Pantano F, Burattini L, Muzzonigro G, Berardi R, Santini D, Cascinu S
Int J Cancer 2014 Aug 15;135(4):763-73. Epub 2013 Nov 18 doi: 10.1002/ijc.28544. PMID: 24127298

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