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Malignant tumor of meninges

MedGen UID:
87594
•Concept ID:
C0348375
•
Neoplastic Process
Synonyms: Cancer, Meningeal; Cancers, Meningeal; Malignant Meningeal Neoplasm; Malignant Meningeal Neoplasms; Meningeal Cancer; Meningeal Cancers; Meningeal Neoplasm, Malignant; Meningeal Neoplasms, Malignant; Neoplasm, Malignant Meningeal; Neoplasms, Malignant Meningeal
SNOMED CT: Malignant meningeal neoplasm (414647009); Malignant tumor of meninges (363497007)
 
Monarch Initiative: MONDO:0021322

Definition

A primary or metastatic malignant tumor occurring in the meninges, which surround the brain and spinal cord. The most common are meningiomas. [from NCI]

Professional guidelines

PubMed

EANO guideline on the diagnosis and management of meningiomas.
Goldbrunner R, Stavrinou P, Jenkinson MD, Sahm F, Mawrin C, Weber DC, Preusser M, Minniti G, Lund-Johansen M, Lefranc F, Houdart E, Sallabanda K, Le Rhun E, Nieuwenhuizen D, Tabatabai G, Soffietti R, Weller M
Neuro Oncol 2021 Nov 2;23(11):1821-1834. doi: 10.1093/neuonc/noab150. PMID: 34181733Free PMC Article
Meningioma: not always a benign tumor. A review of advances in the treatment of meningiomas.
Maggio I, Franceschi E, Tosoni A, Nunno VD, Gatto L, Lodi R, Brandes AA
CNS Oncol 2021 Jun 1;10(2):CNS72. Epub 2021 May 21 doi: 10.2217/cns-2021-0003. PMID: 34015955Free PMC Article
Current treatment options for meningioma.
Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

Recent clinical studies

Etiology

Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients.
Wang JZ, Landry AP, Raleigh DR, Sahm F, Walsh KM, Goldbrunner R, Yefet LS, Tonn JC, Gui C, Ostrom QT, Barnholtz-Sloan J, Perry A, Ellenbogen Y, Hanemann CO, Jungwirth G, Jenkinson MD, Tabatabai G, Mathiesen TI, McDermott MW, Tatagiba M, la Fougère C, Maas SLN, Galldiks N, Albert NL, Brastianos PK, Ehret F, Minniti G, Lamszus K, Ricklefs FL, Schittenhelm J, Drummond KJ, Dunn IF, Pathmanaban ON, Cohen-Gadol AA, Sulman EP, Tabouret E, Le Rhun E, Mawrin C, Moliterno J, Weller M, Bi WL, Gao A, Yip S, Niyazi M; International Consortium on Meningiomas (ICOM), Aldape K, Wen PY, Short S, Preusser M, Nassiri F, Zadeh G
Neuro Oncol 2024 Oct 3;26(10):1742-1780. doi: 10.1093/neuonc/noae082. PMID: 38695575Free PMC Article
Malignant meningiomas.
Fountain DM, Young AMH, Santarius T
Handb Clin Neurol 2020;170:245-250. doi: 10.1016/B978-0-12-822198-3.00044-6. PMID: 32586496
Current treatment options for meningioma.
Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455
Update on meningiomas.
Saraf S, McCarthy BJ, Villano JL
Oncologist 2011;16(11):1604-13. Epub 2011 Oct 25 doi: 10.1634/theoncologist.2011-0193. PMID: 22028341Free PMC Article
Meningioma.
Marosi C, Hassler M, Roessler K, Reni M, Sant M, Mazza E, Vecht C
Crit Rev Oncol Hematol 2008 Aug;67(2):153-71. Epub 2008 Mar 14 doi: 10.1016/j.critrevonc.2008.01.010. PMID: 18342535

Diagnosis

Malignant meningiomas.
Fountain DM, Young AMH, Santarius T
Handb Clin Neurol 2020;170:245-250. doi: 10.1016/B978-0-12-822198-3.00044-6. PMID: 32586496
Atypical meningiomas.
Chen R, Aghi MK
Handb Clin Neurol 2020;170:233-244. doi: 10.1016/B978-0-12-822198-3.00043-4. PMID: 32586495
Management of meningioma.
Euskirchen P, Peyre M
Presse Med 2018 Nov-Dec;47(11-12 Pt 2):e245-e252. Epub 2018 Nov 16 doi: 10.1016/j.lpm.2018.05.016. PMID: 30449639
An overview of meningiomas.
Buerki RA, Horbinski CM, Kruser T, Horowitz PM, James CD, Lukas RV
Future Oncol 2018 Sep;14(21):2161-2177. Epub 2018 Aug 7 doi: 10.2217/fon-2018-0006. PMID: 30084265Free PMC Article
Meningioma.
Marosi C, Hassler M, Roessler K, Reni M, Sant M, Mazza E, Vecht C
Crit Rev Oncol Hematol 2008 Aug;67(2):153-71. Epub 2008 Mar 14 doi: 10.1016/j.critrevonc.2008.01.010. PMID: 18342535

Therapy

Emerging systemic treatment options in meningioma.
Mair MJ, Berghoff AS, Brastianos PK, Preusser M
J Neurooncol 2023 Jan;161(2):245-258. Epub 2022 Oct 1 doi: 10.1007/s11060-022-04148-8. PMID: 36181606Free PMC Article
EANO guideline on the diagnosis and management of meningiomas.
Goldbrunner R, Stavrinou P, Jenkinson MD, Sahm F, Mawrin C, Weber DC, Preusser M, Minniti G, Lund-Johansen M, Lefranc F, Houdart E, Sallabanda K, Le Rhun E, Nieuwenhuizen D, Tabatabai G, Soffietti R, Weller M
Neuro Oncol 2021 Nov 2;23(11):1821-1834. doi: 10.1093/neuonc/noab150. PMID: 34181733Free PMC Article
Malignant meningiomas.
Fountain DM, Young AMH, Santarius T
Handb Clin Neurol 2020;170:245-250. doi: 10.1016/B978-0-12-822198-3.00044-6. PMID: 32586496
Leptomeningeal metastasis.
Taillibert S, Chamberlain MC
Handb Clin Neurol 2018;149:169-204. doi: 10.1016/B978-0-12-811161-1.00013-X. PMID: 29307353
Meningioma.
Marosi C, Hassler M, Roessler K, Reni M, Sant M, Mazza E, Vecht C
Crit Rev Oncol Hematol 2008 Aug;67(2):153-71. Epub 2008 Mar 14 doi: 10.1016/j.critrevonc.2008.01.010. PMID: 18342535

Prognosis

Stereotactic Radiosurgery for Intracranial Meningiomas.
Pikis S, Mantziaris G, Dumot C, Xu Z, Sheehan J
Neurosurg Clin N Am 2023 Jul;34(3):455-462. Epub 2023 Apr 7 doi: 10.1016/j.nec.2023.02.010. PMID: 37210134
Epidemiology of brain metastases and leptomeningeal disease.
Lamba N, Wen PY, Aizer AA
Neuro Oncol 2021 Sep 1;23(9):1447-1456. doi: 10.1093/neuonc/noab101. PMID: 33908612Free PMC Article
Fourth Ventricular Meningiomas.
Luo W, Xu Y, Yang J, Liu Z, Liu H
World Neurosurg 2019 Jul;127:e1201-e1209. Epub 2019 Apr 17 doi: 10.1016/j.wneu.2019.04.097. PMID: 31004862
Epidemiology of meningiomas.
Baldi I, Engelhardt J, Bonnet C, Bauchet L, Berteaud E, Grüber A, Loiseau H
Neurochirurgie 2018 Mar;64(1):5-14. Epub 2014 Sep 22 doi: 10.1016/j.neuchi.2014.05.006. PMID: 25249493
Neoplastic meningitis.
Chamberlain MC
J Clin Oncol 2005 May 20;23(15):3605-13. doi: 10.1200/JCO.2005.01.131. PMID: 15908671

Clinical prediction guides

Histopathologic and Molecular Evaluation of Meningioma.
Davidson C
Neurosurg Clin N Am 2023 Jul;34(3):311-318. Epub 2023 Apr 4 doi: 10.1016/j.nec.2023.02.001. PMID: 37210122
Management strategies and clinical follow-up of pregnant women with intracranial meningioma.
Dumitru AE, Panaitescu A, Iancu G, Paslaru FG, Paslaru AC, Gorgan RM, Peltecu G
J Med Life 2021 Jan-Mar;14(1):2-6. doi: 10.25122/jml-2021-0012. PMID: 33767778Free PMC Article
Current treatment options for meningioma.
Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455
Secretory meningiomas.
Colakoğlu N, Demirtaş E, Oktar N, Yüntem N, Islekel S, Ozdamar N
J Neurooncol 2003 May;62(3):233-41. doi: 10.1023/a:1023319407645. PMID: 12777074
Cystic meningioma.
el-Fiki M, el-Henawy Y, Abdel-Rahman N
Acta Neurochir (Wien) 1996;138(7):811-7. doi: 10.1007/BF01411258. PMID: 8869708

Recent systematic reviews

Fluorescence-guided resection of intradural spinal tumors: a systematic review and meta-analysis.
Albalkhi I, Shafqat A, Bin-Alamer O, Abou Al-Shaar AR, Mallela AN, Fernández-de Thomas RJ, Zinn PO, Gerszten PC, Hadjipanayis CG, Abou-Al-Shaar H
Neurosurg Rev 2023 Dec 12;47(1):10. doi: 10.1007/s10143-023-02230-x. PMID: 38085385
Liquid biopsy in the setting of leptomeningeal metastases: a systematic review and meta-analysis.
Wijaya JH, Patel UD, Quintero-Consuegra MD, Aguilera-Peña MP, Madriñán-Navia HJ, Putra AW, July J, Kataria S
J Neurooncol 2023 Dec;165(3):431-438. Epub 2023 Nov 29 doi: 10.1007/s11060-023-04519-9. PMID: 38019327
Pachymeningeal disease: a systematic review and metanalysis.
Gutiérrez-Valencia E, Sánchez I, Valles A, Díaz O, F González T, Balderrama R, Fuentes J, Ruiz V, Rodríguez J, Saavedra C, Velázquez-Pulido L, Cadavid E, E Ayala-Hernández L, Villalvazo A, H Bayardo L, Jamora K, Kalyvas A, Yang K, Millar BA, B Shultz D
J Neurooncol 2023 Oct;165(1):29-39. Epub 2023 Oct 10 doi: 10.1007/s11060-023-04476-3. PMID: 37815737
Combined petrosal approach: a systematic review and meta-analysis of surgical complications.
Giammattei L, Starnoni D, Peters D, George M, Messerer M, Daniel RT
Neurosurg Rev 2023 Jul 13;46(1):172. doi: 10.1007/s10143-023-02072-7. PMID: 37439884Free PMC Article
Meningioma systematic reviews and meta-analyses: an assessment of reporting and methodological quality.
George AM, Gupta S, Keshwara SM, Mustafa MA, Gillespie CS, Richardson GE, Steele AC, Zamanipoor Najafabadi AH, Dirven L, Marson AG, Islim AI, Jenkinson MD, Millward CP
Br J Neurosurg 2022 Dec;36(6):678-685. Epub 2022 Oct 20 doi: 10.1080/02688697.2022.2115008. PMID: 36263847

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