Similar studies for GEO DataSets (Select 200050833) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Links from GEO DataSets

Items: 19

Select item 2000508331.

Analysis of age-related vascular gene expression in mice

(Submitter supplied) Analyses of the age-related changes that occur at a gene expression level and transcriptional profile have not been elucidated in depth. To determine the changes of the vascular transcriptome, we conducted gene expression microarray experiments on aortas of adult and old mice, in which age-related vascular dysfunction was confirmed by increased stiffness and associated systolic hypertension

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
12 Samples

Download data: TXT

Series

Accession:: GSE50833

ID:: 200050833

Select item 2000665722.

Analysis of the vascular gene expression profile following a chronic nitrate supplementation in old mice

(Submitter supplied) Analyses of the vascular changes that occur following a chronic nitrate supplementation in old mice at a gene expression level and transcriptional profile have not been elucidated in depth. To determine the changes of the vascular transcriptome, we conducted gene expression microarray experiments on aortas of old and old nitrate treated mice, in which age-related vascular dysfunction was confirmed by endothelial dysfunction.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
11 Samples

Download data: TXT

Series

Accession:: GSE66572

ID:: 200066572

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000005653.

mouse RPE/choroid age comparison - ATLAS arrays

(Submitter supplied) Young mice were compared to old mice (2 month vs 24 month) to determine gene changes that occur with aging in the mouse retinal pigmented epithelium/choroid of the eye. Keywords = retinal pigmented epithelium Keywords = aging Keywords = choroid Keywords: other

Organism:: Mus musculus

Type:: Expression profiling by array

Platforms:: GPL144 GPL145
12 Samples

Download data

Series

Accession:: GSE565

ID:: 200000565

Select item 2000064854.

Expression data from olfactory epithelium of Harlequin mutant mice compared to littermate controls

(Submitter supplied) Microarray analysis of gene expression in the olfactory epithelium of Harlequin mouse as a model of oxidative-stress induced neurodegeneration of olfactory sensory neurons Keywords: comparison of gene expression level in unperturbed tissue of mutant vs. control mouse

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3365
Platform:: GPL1261
6 Samples

Download data: CEL

Series

Accession:: GSE6485

ID:: 200006485

Select item 33655.

Oxidative-stress induced neurodegeneration in Harlequin mutant: olfactory epithelium

Analysis of olfactory epithelium from Harlequin mutant, a model of oxidative stress (OS)-induced neurodegeneration. OS in the olfactory system is a major factor associated with age-related olfactory impairment. Results provide insight into the molecular basis of OS-associated olfactory aging.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE6485
6 Samples

Download data: CEL

DataSet

Accession:: GDS3365

ID:: 3365

Select item 2000015606.

Aortas of mice on high fat diet

(Submitter supplied) Expression profiles in aortas isolated from mouse strains C3H.2/HeJ and C57.2Bl/6. Mice were were either on a high fat diet or normal diet for 0, 4, 10, 24, or 40 weeks. Keywords: other

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS735
Platform:: GPL891
54 Samples

Download data

Series

Accession:: GSE1560

ID:: 200001560

Select item 7357.

High fat diet effect on aorta: time course

Comparison of gene expression in aortas of C57BL/6 and C3H/HeJ fed identical high fat diets at 0, 4, 8, 24, and 40 weeks. C57BL/6 has a greater tendency than C3H/HeJ to develop atherosclerotic aortic lesions when both fed identical high fat diets.

Organism:: Mus musculus

Type:: Expression profiling by array, log ratio, 2 growth protocol, 2 strain, 5 time sets

Platform:: GPL891
Series:: GSE1560
54 Samples

Download data

DataSet

Accession:: GDS735

ID:: 735

Select item 2000250768.

Hypothalamic expression differences between hypertensive BPH/2J and normotensive BPN/3J mouse strains

(Submitter supplied) Identification of hypothalamic genes whose expression differs between high blood pressure (BPH/2J) and normal blood pressure (BPN/3J) Schlager mouse strains at age 6 weeks (young) and 26 weeks (mature) using Affymetrix GeneChip® Mouse Gene 1.0 ST Arrays.

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3895
Platform:: GPL6246
24 Samples

Download data: CEL

Series

Accession:: GSE25076

ID:: 200025076

Select item 38959.

BPH/J2 model of neurogenic hypertension: hypothalamus

Analysis of hypothalamus from young (6 week-old) and adult (26 week-old) BPH/2J hypertensive males and age-/gender-matched normotensive BPN/3J controls. Results provide insight into molecular mechanisms underlying early and established neurogenic hypertension in hypothalamus.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 age, 2 disease state, 2 strain sets

Platform:: GPL6246
Series:: GSE25076
24 Samples

Download data: CEL

DataSet

Accession:: GDS3895

ID:: 3895

Select item 20000240110.

Gene expression in Hypotension

(Submitter supplied) Rat kidney in normo- and hypotensive animals. Keywords: parallel sample

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS1251
Platform:: GPL341
9 Samples

Download data: CEL, EXP, RPT

Series

Accession:: GSE2401

ID:: 200002401

Select item 125111.

Acute hypotension effect on kidneys

Expression profiling of kidneys of 12 week old normotensive Wistar-Kyoto males subjected to acute hypotension by withdrawing 3 ml of blood. Results provide insight into vasoregulatory mechanisms and the genetics and physiology of blood pressure regulation.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 stress sets

Platform:: GPL341
Series:: GSE2401
9 Samples

Download data: CEL, EXP, RPT

DataSet

Accession:: GDS1251

ID:: 1251

Select item 20000036212.

Normal human muscle - U133 arrays

(Submitter supplied) vastus lateralis biopsies were obtained from healthy subjects, either young adults (20-29 yr old) or older (65-75 yr old) Keywords = muscle Keywords = aging Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS287 GDS288
Platforms:: GPL96 GPL97
30 Samples

Download data

Series

Accession:: GSE362

ID:: 200000362

Select item 28813.

Muscle function and aging - male (HG-U133B)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 age sets

Platform:: GPL97
Series:: GSE362
15 Samples

Download data

DataSet

Accession:: GDS288

ID:: 288

Select item 28714.

Muscle function and aging - male (HG-U133A)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 age sets

Platform:: GPL96
Series:: GSE362
15 Samples

Download data

DataSet

Accession:: GDS287

ID:: 287

Select item 20001074815.

Expression data from brain tissue of Rattus norvegicus treated with D-Serine

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS3643
Platform:: GPL1355
24 Samples

Download data: CEL

Series

Accession:: GSE10748

ID:: 200010748

Select item 364316.

D-serine effect on the brain: dose response

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 agent, 6 dose sets

Platform:: GPL1355
Series:: GSE10748
24 Samples

Download data: CEL

DataSet

Accession:: GDS3643

ID:: 3643

Select item 20011115917.

Tissue-specific features of oxidative stress-associated gene expression in a healthy mouse model

(Submitter supplied) Oxidative stress is a common phenomenon and is linked to a wide range of diseases and pathological processes. Tissue-specific variation in redox signaling and cellular responses to oxidative stress may be associated with vulnerability to toxic agents and carcinogenic exposures. In order to provide a basis for tissue-specific difference, we examined the tissue-specific transcriptional features of 101 oxidative stress-associated genes in 10 different tissues and organs of healthy mice under physiological conditions. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
50 Samples

Download data: CEL

Series

Accession:: GSE111159

ID:: 200111159

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005401518.

Expression data from male and female Schlager hypertensive (BPH/2J) and normotensive (BPN/3J) kidneys

(Submitter supplied) Analysis of kidneys from 12 week BPH/2J hypertensive and age matched normotensive BPN/3J controls - males and females. The results provide insights into the genes that are involved in hypertension in both males and females, as well as highlight mechanisms that underlye sex differences in hypertension. We show that female data can be used to refine candidate genes and pathways, as well as highlight potential mechanisms to explain the differences in prevalence and severity of disease between the sexes.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11533
24 Samples

Download data: CEL

Series

Accession:: GSE54015

ID:: 200054015

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20006722019.

AginAging: a portrait from gene expression profile in blood cells: a portrait from gene expression profile in blood cells.

(Submitter supplied) In almost every countries the proportion of people over 60 years is growing faster that any other age group. Increased life expectancy is leading to the characterization of specific aspects of aging for the various physiological systems. The study of healthy aging is important to design strategies capable to maximize the health and to prevent chronic diseases in older people. Immunosenscence reflects the age-related changes of the immune system and the reduced capacity of elderly people to cope with new infections. more...