Similar studies for GEO DataSets (Select 200225289) - GEO DataSets

(Submitter supplied) An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from skin samples of beluga whales, Maui's dolphin, and humpback whale. Tissue: Skin

Organism:: Balaenoptera musculus; Megaptera novaeangliae; Delphinapterus leucas; Mus musculus; Rattus norvegicus; Cephalorhynchus hectori maui; Homo sapiens; Physeter catodon

Type:: Methylation profiling by genome tiling array

Platform:: GPL28271
143 Samples

Download data: IDAT

Series

Accession:: GSE164465

ID:: 200164465

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Select item 2001842164.

Methylation studies in roe deer

(Submitter supplied) An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from blood samples of roe deer n=94 blood samples

Organism:: Capreolus capreolus; Homo sapiens; Mus musculus; Rattus norvegicus

Type:: Methylation profiling by array

Platform:: GPL28271
94 Samples

Download data: CSV, DOCX, IDAT

Series

Accession:: GSE184216

ID:: 200184216

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Select item 2001733305.

Methylation clocks for age estimation in toothed whales and dolphins

(Submitter supplied) An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from several tissues (skin, blood) in toothed whales and dolphins. Tissues: skin and blood.

Organism:: Delphinus delphis; Cephalorhynchus commersonii; Orcinus orca; Tursiops truncatus; Globicephala macrorhynchus; Steno bredanensis; Delphinapterus leucas; Mus musculus; Rattus norvegicus; Lagenorhynchus obliquidens; Homo sapiens; Phocoena phocoena

Type:: Methylation profiling by genome tiling array

Platform:: GPL28271
545 Samples

Download data: IDAT, TXT

Series

Accession:: GSE173330

ID:: 200173330

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Select item 2001379576.

DNA methylation clocks as a predictor for ageing and age estimation in naked mole-rats, Heterocephalus glaber

(Submitter supplied) The naked mole-rat, Heterocephalus glaber (NMR), the longest-lived rodent with a maximum possible lifespan exceeding 33 years, is emerging as an important non-model organism for the study of longevity and healthspan. As such it is of significance and interest in the study of biomarkers for ageing in mammals. Recent breakthroughs in this field have indicated that ‘epigenetic clocks’ based on the temporal accumulation of DNA methylation at specific genomic sites can enable accurate age estimates for tissues across the lifespan of an individual. more...

Organism:: Heterocephalus glaber

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL27526
39 Samples

Download data: CSV

Series

Accession:: GSE137957

ID:: 200137957

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Select item 2001042177.

The rate of ageing-associated DNA methylation dynamics is a molecular readout of lifespan variation amongst mammalian species [Macaque_450k]

(Submitter supplied) We used blood samples from Macaque to determine rate of change of methylation with respect to age.

Organism:: Macaca mulatta; Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
6 Samples

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Series

Accession:: GSE104217

ID:: 200104217

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Select item 2001042168.

The rate of ageing-associated DNA methylation dynamics is a molecular readout of lifespan variation amongst mammalian species [TC1_450k]

(Submitter supplied) We used liver samples from TC1 Mice to determine rate of change of methylation with respect to age.

Organism:: Homo sapiens; Mus musculus

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
6 Samples

Download data: TXT

Series

Accession:: GSE104216

ID:: 200104216

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Select item 2001042159.

The rate of ageing-associated DNA methylation dynamics is a molecular readout of lifespan variation amongst mammalian species [Bis-PCR: naked mole-rat]

(Submitter supplied) We used liver samples from Naked Mole Rat to determine rate of change of methylation with respect to age.

Organism:: Heterocephalus glaber

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL24046
24 Samples

Download data: TXT

Series

Accession:: GSE104215

ID:: 200104215

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Select item 20008605910.

The rate of ageing-associated DNA methylation dynamics is a molecular readout of lifespan variation amongst mammalian species

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Macaca mulatta; Homo sapiens; Canis lupus familiaris; Mus musculus; Heterocephalus glaber

Type:: Methylation profiling by high throughput sequencing; Methylation profiling by genome tiling array

Platforms:: GPL24046 GPL13534 GPL22370
84 Samples

Download data: TXT

Series

Accession:: GSE86059

ID:: 200086059

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Select item 20008605811.

The rate of ageing-associated DNA methylation dynamics is a molecular readout of lifespan variation amongst mammalian species [Bis-PCR: dog]

(Submitter supplied) We used buccal samples from two different dog breeds with well established differences in average lifespan to perform genome-scale identification of ageing-associated differentially methylated positions (aDMPs) in a total of 48 different dogs. A significant proportion of aDMPs that gained methylation with age replicated in an independent cohort. Furthermore, we also show that human aDMPs show similar ageing-associated dynamics at the homologous genomic regions in the dog. more...

Organism:: Canis lupus familiaris

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL22370
48 Samples

Download data: TXT

Series

Accession:: GSE86058

ID:: 200086058

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20019066312.

Methylation studies in common marmoset

(Submitter supplied) DNA methylation data from common marmosets (Callithrix jacchus) profiled on the mammalian methylation array (HorvathMammalMethylChip40) which focuses on highly conserved CpGs across mammalian species. Rapamycin study in a subset of animals.

Organism:: Callithrix jacchus; Rattus norvegicus; Homo sapiens; Mus musculus

Type:: Methylation profiling by array

Platform:: GPL28271
96 Samples

Download data: CSV, DOCX, IDAT

Series

Accession:: GSE190663

ID:: 200190663

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Select item 20019066413.

Methylation studies in rhesus macaque

(Submitter supplied) DNA methylation data from rhesus macaque (Macaca mulatta) profiled on the mammalian methylation array (HorvathMammalMethylChip40) which focuses on highly conserved CpGs across mammalian species. We profiled n = 283 tissue samples (blood, skin, adipose, kidney, liver, lung, muscle, and cerebral cortex)

Organism:: Rattus norvegicus; Macaca mulatta; Homo sapiens; Mus musculus

Type:: Methylation profiling by array

Platform:: GPL28271
283 Samples

Download data: CSV, DOCX, IDAT

Series

Accession:: GSE190664

ID:: 200190664

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Select item 20019066014.

Methylation studies in the vervet monkey

(Submitter supplied) DNA methylation data from vervet cerebral cortex, blood, and liver using highly conserved mammalian CpGs represented on the mammalian methylation array (HorvathMammalMethylChip40). We selected a total of 240 samples representing the entire vervet lifespan, from neonatal to senile stages: 144 samples from the peripheral blood, 48 samples from the liver, and 48 samples from the cortical brain area BA10.

Organism:: Mus musculus; Rattus norvegicus; Homo sapiens; Chlorocebus sabaeus

Type:: Methylation profiling by array

Platform:: GPL28271
240 Samples

Download data: CSV, DOCX, IDAT

Series

Accession:: GSE190660

ID:: 200190660

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Select item 20010022715.

The Australian Mammographic Density Twins and Sisters Study - DNA methylation data

(Submitter supplied) DNA methylation data for 479 women from 130 families including 66 monozygotic twin pairs, 66 dizygotic twin pairs and 215 sisters of twins.

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL13534
479 Samples

Download data: TXT

Series

Accession:: GSE100227

ID:: 200100227

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Select item 20019314216.

Development of a novel aging clock based on chromatin accessibility

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL24676
316 Samples

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Series

Accession:: GSE193142

ID:: 200193142

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Select item 20019314117.

Development of a novel aging clock based on chromatin accessibility [RNA-seq]

(Submitter supplied) The establishment of highly accurate aging clocks based on DNA methylation highlighted the strong link between epigenetic alterations and aging. However, connecting methylation clocks to physiological changes is not straightforward. Transcriptomics and proteomics clocks on the other hand are directly connected to cellular function, yet they do not allow us to understand underlying epigenetic mechanisms. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
159 Samples

Download data: CSV

Series

Accession:: GSE193141

ID:: 200193141

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Select item 20019314018.

Development of a novel aging clock based on chromatin accessibility [ATAC-seq]

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL24676
157 Samples

Download data: TXT

Series

Accession:: GSE193140

ID:: 200193140

PubMed Full text in PMC Similar studies

Select item 20019997919.

Genetic Loci and Metabolic States Associated With Murine Epigenetic Aging

(Submitter supplied) DNA methylation measured in mice belonging to the BXD Family using the HorvathMammalMethylChip40

Organism:: Mus musculus; Rattus norvegicus; Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL28271
339 Samples

Download data: IDAT

Series

Accession:: GSE199979

ID:: 200199979

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Select item 20013280420.

Dysfunctional epigenetic aging of the normal colon and colorectal cancer risk

(Submitter supplied) Genome wide DNA methylation profiling of normal colon samples. The Illumina Infinium HumanMethylation450 and EPIC Beadchip arrays were used to obtain DNA methylation profiles across approximately 450,000 and 850,000 CpGs. Samples were from nomal colons of 334 subjects with low, medium or high CRC risk according to their personal adenoma or cancer history.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platforms:: GPL21145 GPL13534
334 Samples

Download data: IDAT

Series

Accession:: GSE132804

ID:: 200132804

PubMed Full text in PMC Similar studies Analyze with GEO2R

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