GEO DataSets

(Submitter supplied) Dietary restriction has shown benefits in physiological, metabolic, and molecular signatures associated with aging. In mice, periodic dietary restriction, that accompanies cyclical periods of reduced calories, mitigates aging phenotypes, yet the effects of this periodic restriction in higher order, genetically heterogenous mammals, have not been investigated. Reducing caloric intake in middle-aged Rhesus Macaques for four days followed by ad libitum eating for ten days, repeated for six cycles, led to significant changes in body composition, metabolome, and microbiome of the restricted monkeys compared to their ad libitum fed (age and sex matched) controls. more...

Organism:

gut metagenome

Type:

Other

Platform:

GPL33529

140 Samples

Download data: TXT

(Submitter supplied) Background:Diversion colitis (DC) is a non-specific inflammation in the intestinal mucosa with colonic dysfunction after low anterior resection of rectal cancer. It is newly proposed in recent years. With the gradual prolongation time of the ileostomy status, the condition of DC may become increasingly severe. However, the corresponding pathogenesis of DC has not been clarified yet. Methods:Clinical information were collected from patients with low rectal cancer admitted to the Department of Anorectal Surgery, Changzheng Hospital, from April 2017 to April 2019. more...

Organism:

gut metagenome

Type:

Other

Platform:

GPL29420

40 Samples

Download data: XLSX

(Submitter supplied) Illumina high-throughput sequencing was used to analyse the intestinal bacteria of these two species during different wintering periods at Shengjin Lake. We tested whether contact time enhances the trans-species spread of gut bacteria. Our results indicate that although intestinal microflora of hooded crane and the bean goose were different, direct or indirect contact in the mixed-species flock caused the spread of gut bacteria trans-species, and a very high proportion of common pathogens among these two hosts.

Organism:

gut metagenome

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29420

111 Samples

Download data: TXT

(Submitter supplied) We used a DNA microarray chip covering 369 resistance types to investigate the relation of antibiotic resistance gene diversity with humans’ age. Metagenomic DNA from fecal samples of 123 healthy volunteers of four different age groups, i.e. pre-school Children (CH), School Children (SC), High School Students (HSS) and Adults (AD) were used for hybridization. The results showed that 80 different gene types were recovered from the 123 individuals gut microbiota, among which 25 were present in CH, 37 in SC, 58 in HSS and 72 in AD. more...

Organism:

human gut metagenome; gut metagenome

Type:

Genome variation profiling by array

Platform:

GPL18168

123 Samples

Download data: PAIR

(Submitter supplied) Here, we report the use of Illumina RNA-Seq for investigating the physiology of the digestive-tract microbiome within the medicinal leech, Hirudo verbana. About 12 million cDNA reads were mapped against the genomes of the two dominant members of this simple microbiome. Results suggested that the most abundant, yet uncultured Rikenella-like bacterium forages host mucin glycans and ferments the carbohydrates to acetate that is secreted into the environment. more...

Organism:

Hirudo verbana; gut metagenome

Type:

Expression profiling by high throughput sequencing

Platform:

GPL10862

2 Samples

Download data: TXT

(Submitter supplied) NimbleGen design name: 091124_micro_BZ_EXP_HX12, NimbleGen design ID: 10987 An detection design for 2916 antibiotic resistance genes from ARDB with twelve 60-mer probe pairs (PM/MM) per gene. Each probe is replicated 3 times. The design includes random GC control probes. The .ndf and .ngd files are linked below as supplementary files. However, please note that not all genes in the ngd file are represented in the platform data table. more...

Organism:

gut metagenome

1 Series

123 Samples

Download data: NCD, NDF, NGD