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B-Cell Proliferation of Uncertain Malignant Potential

MedGen UID:
231391
•Concept ID:
C1332363
•
Neoplastic Process

Definition

A B-cell lymphoproliferative disorder with uncertain malignant potential. The representative example of this category is lymphomatoid granulomatosis. [from NCI]

Recent clinical studies

Etiology

So-called "Lennert's lymphoma": is it a clinicopathologic entity?
Kim H, Nathwani BN, Rappaport H
Cancer 1980 Mar 15;45(6):1379-99. doi: 10.1002/1097-0142(19800315)45:6<1379::aid-cncr2820450617>3.0.co;2-#. PMID: 6986978

Diagnosis

Morphological and Molecular Study of Hybrid Oncocytic/Chromophobe Tumor of the Kidney Associated with Sporadic Renal Oncocytosis and Chronic B-Cell Lymphocytic Leukemia: The Possible Contribution of Lymphoma to Renal Oncocytosis.
Idoate MA, Trigo I, Saenz de Zaitigui J, Pérez-Pérez M, Ríos JJ
Pathobiology 2021;88(4):313-322. Epub 2021 Apr 21 doi: 10.1159/000515215. PMID: 33882490
Saliva-omics in plasma cell disorders- Proof of concept and potential as a non-invasive tool for monitoring disease burden.
Tierney C, Bazou D, Lê G, Dowling P, O'Gorman P
J Proteomics 2021 Jan 16;231:104015. Epub 2020 Oct 14 doi: 10.1016/j.jprot.2020.104015. PMID: 33068749
Premalignant Clonal Hematopoietic Proliferations.
Nardi V, Kuo FC, Hasserjian RP
Am J Clin Pathol 2019 Aug 1;152(3):347-358. doi: 10.1093/ajcp/aqz079. PMID: 31305863
Atypical uterine leiomyoma: a case report and review of the literature.
Manxhuka-Kerliu S, Kerliu-Saliu I, Sahatciu-Meka V, Kerliu L, Shahini L
J Med Case Rep 2016 Jan 22;10:22. doi: 10.1186/s13256-016-0800-3. PMID: 26801982Free PMC Article
A case of lymphomatoid granulomatosis followed for 14 months on the basis of clinical and histological findings.
Okuda T, Akai F, Kataoka K, Taneda M
Brain Tumor Pathol 2008;25(1):33-8. Epub 2008 Apr 16 doi: 10.1007/s10014-007-0227-z. PMID: 18415664

Therapy

Knockdown of BAP31 Overcomes Hepatocellular Carcinoma Doxorubicin Resistance through Downregulation of Survivin.
Liu J, Zhang Q, Wang C, Yang J, Yang S, Wang T, Wang B
Int J Mol Sci 2023 Apr 21;24(8) doi: 10.3390/ijms24087622. PMID: 37108785Free PMC Article
A case of lymphomatoid granulomatosis followed for 14 months on the basis of clinical and histological findings.
Okuda T, Akai F, Kataoka K, Taneda M
Brain Tumor Pathol 2008;25(1):33-8. Epub 2008 Apr 16 doi: 10.1007/s10014-007-0227-z. PMID: 18415664

Clinical prediction guides

So-called "Lennert's lymphoma": is it a clinicopathologic entity?
Kim H, Nathwani BN, Rappaport H
Cancer 1980 Mar 15;45(6):1379-99. doi: 10.1002/1097-0142(19800315)45:6<1379::aid-cncr2820450617>3.0.co;2-#. PMID: 6986978

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