U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lacrimal duct cancer

MedGen UID:
57795
•Concept ID:
C0153631
•
Neoplastic Process
Synonyms: cancer of lacrimal drainage system; lacrimal drainage system cancer; lacrimal duct cancer; malignant lacrimal drainage system neoplasm; Malignant Lacrimal Duct Neoplasm; malignant lacrimal duct neoplasm; Malignant Lacrimal Duct Tumor; malignant lacrimal duct tumor; malignant lacrimal duct tumour; Malignant Nasolacrimal Duct Neoplasm; malignant neoplasm of lacrimal drainage system; Malignant Neoplasm of Lacrimal Duct; Malignant neoplasm of lacrimal duct; malignant neoplasm of lacrimal duct; Malignant Neoplasm of the Lacrimal Duct; malignant neoplasm of the lacrimal duct; Malignant Tumor of Lacrimal Duct; malignant tumor of lacrimal duct; Malignant Tumor of the Lacrimal Duct; malignant tumor of the lacrimal duct; malignant tumour of lacrimal duct; malignant tumour of the lacrimal duct
SNOMED CT: Malignant neoplasm of lacrimal duct (188274004)
 
Monarch Initiative: MONDO:0001580

Definition

A primary or metastatic malignant neoplasm affecting the lacrimal duct. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLacrimal duct cancer

Professional guidelines

PubMed

Treatment of congenital nasolacrimal duct cyst: the role of endoscopic marsupialisation.
Rampinelli V, Ferrari M, Zorzi S, Berlucchi M
Acta Otorhinolaryngol Ital 2020 Oct;40(5):377-382. doi: 10.14639/0392-100X-N0759. PMID: 33299228Free PMC Article
Treatment outcomes after definitive radio(chemo)therapy for 17 lacrimal sac squamous cell carcinoma.
Song X, He H, Zhu Y, Wang S, Wang J, Wang W, Li Y
Br J Radiol 2020 Nov 1;93(1115):20190633. Epub 2020 Oct 6 doi: 10.1259/bjr.20190633. PMID: 32970475Free PMC Article
Conservative management of congenital dacryocystocele: resolution and complications.
Lee MJ, Park J, Kim N, Choung HK, Khwarg SI
Can J Ophthalmol 2019 Aug;54(4):421-425. Epub 2018 Oct 23 doi: 10.1016/j.jcjo.2018.08.006. PMID: 31358138

Recent clinical studies

Etiology

Recurrent lacrimal gland pleomorphic adenoma.
Reilly S, Ellard R, O'Sullivan M, Khan R, Kennedy S
Orbit 2023 Dec;42(6):635-640. Epub 2022 May 12 doi: 10.1080/01676830.2022.2064515. PMID: 35546531
Carcinomas of the lacrimal drainage system.
Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Evaluation and Management of Chemotherapy-Induced Epiphora, Punctal and Canalicular Stenosis, and Nasolacrimal Duct Obstruction.
Mansur C, Pfeiffer ML, Esmaeli B
Ophthalmic Plast Reconstr Surg 2017 Jan/Feb;33(1):9-12. doi: 10.1097/IOP.0000000000000745. PMID: 27429222
Current treatment of lacrimal gland carcinoma.
Woo KI, Kim YD, Sa HS, Esmaeli B
Curr Opin Ophthalmol 2016 Sep;27(5):449-56. doi: 10.1097/ICU.0000000000000301. PMID: 27273588

Diagnosis

Carcinomas of the lacrimal drainage system.
Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
An Update on Tumors of the Lacrimal Gland.
Andreasen S, Esmaeli B, Holstein SL, Mikkelsen LH, Rasmussen PK, Heegaard S
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):159-172. doi: 10.22608/APO.201707. PMID: 28399336
Tumors of the lacrimal gland.
von Holstein SL, Rasmussen PK, Heegaard S
Semin Diagn Pathol 2016 May;33(3):156-63. Epub 2015 Oct 9 doi: 10.1053/j.semdp.2015.10.002. PMID: 26849904
Canaliculops.
Sacks E, Jakobiec FA, Dodick J
Ophthalmology 1987 Jan;94(1):78-81. doi: 10.1016/s0161-6420(87)33499-2. PMID: 3561961

Therapy

Lymphoproliferative tumors involving the lacrimal drainage system: a major review.
Singh S, Ali MJ
Orbit 2020 Aug;39(4):276-284. Epub 2019 Jul 3 doi: 10.1080/01676830.2019.1634104. PMID: 31267826
Congenital bilateral dacryocystocele.
Carneiro de Sousa P, Neves M, Duarte D, Azevedo P
Eur Ann Otorhinolaryngol Head Neck Dis 2019 Feb;136(1):41-42. Epub 2018 Oct 15 doi: 10.1016/j.anorl.2017.10.006. PMID: 30337239
Evaluation and Management of Chemotherapy-Induced Epiphora, Punctal and Canalicular Stenosis, and Nasolacrimal Duct Obstruction.
Mansur C, Pfeiffer ML, Esmaeli B
Ophthalmic Plast Reconstr Surg 2017 Jan/Feb;33(1):9-12. doi: 10.1097/IOP.0000000000000745. PMID: 27429222
Mycotic Infections of the Eye.
Słowik M, Biernat MM, Urbaniak-Kujda D, Kapelko-Słowik K, Misiuk-Hojło M
Adv Clin Exp Med 2015 Nov-Dec;24(6):1113-7. doi: 10.17219/acem/50572. PMID: 26771986
Docetaxel-associated epiphora.
Kintzel PE, Michaud LB, Lange MK
Pharmacotherapy 2006 Jun;26(6):853-67. doi: 10.1592/phco.26.6.853. PMID: 16716138

Prognosis

The poor prognosis of lacrimal gland adenocarcinoma: a clinical study and literature review.
Liu R, Ren T, Li J, Wang N, Xu L, Guo Q, Zhang H, Ma J
J Cancer Res Clin Oncol 2024 Jan 23;150(1):26. doi: 10.1007/s00432-023-05510-7. PMID: 38263473Free PMC Article
Lymphoproliferative Tumors of the Ocular Adnexa.
Verdijk RM
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):132-142. doi: 10.22608/APO.2016209. PMID: 28399341
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Tumors of the lacrimal gland.
von Holstein SL, Rasmussen PK, Heegaard S
Semin Diagn Pathol 2016 May;33(3):156-63. Epub 2015 Oct 9 doi: 10.1053/j.semdp.2015.10.002. PMID: 26849904
Mycotic Infections of the Eye.
Słowik M, Biernat MM, Urbaniak-Kujda D, Kapelko-Słowik K, Misiuk-Hojło M
Adv Clin Exp Med 2015 Nov-Dec;24(6):1113-7. doi: 10.17219/acem/50572. PMID: 26771986

Clinical prediction guides

The poor prognosis of lacrimal gland adenocarcinoma: a clinical study and literature review.
Liu R, Ren T, Li J, Wang N, Xu L, Guo Q, Zhang H, Ma J
J Cancer Res Clin Oncol 2024 Jan 23;150(1):26. doi: 10.1007/s00432-023-05510-7. PMID: 38263473Free PMC Article
Dacryops - A review.
Tanaboonyawat S, Idowu OO, Copperman TS, Vagefi MR, Kersten RC
Orbit 2020 Apr;39(2):128-134. Epub 2019 Sep 12 doi: 10.1080/01676830.2019.1608564. PMID: 31512543
Clinical management and outcomes of lacrimal sac squamous cell carcinoma.
Song X, Wang S, Wang J, Wang W, Wang S, Yang G, Li J, Zhu Y, Chen F, Zhu W
Head Neck 2019 Apr;41(4):974-981. Epub 2019 Jan 10 doi: 10.1002/hed.25529. PMID: 30629760
IgG4-related orbital disease.
Flores Balverdi J, Baenas DF, Riscanevo NC, Sánchez AV, Figueroa Rosales R, Alvarellos A
Arch Soc Esp Oftalmol (Engl Ed) 2018 Oct;93(10):494-496. Epub 2018 Jun 1 doi: 10.1016/j.oftal.2018.04.003. PMID: 29866378
Mycotic Infections of the Eye.
Słowik M, Biernat MM, Urbaniak-Kujda D, Kapelko-Słowik K, Misiuk-Hojło M
Adv Clin Exp Med 2015 Nov-Dec;24(6):1113-7. doi: 10.17219/acem/50572. PMID: 26771986

Recent systematic reviews

Recurrence rate of pleomorphic adenoma of the lacrimal gland: systematic review and meta-analysis.
Van Swol EG, Gupta A, Nguyen SA, Eiseman AS
Orbit 2024 Apr;43(2):208-216. Epub 2023 Oct 23 doi: 10.1080/01676830.2023.2269252. PMID: 37870812
Ectopic Lacrimal Gland Tissue: A Systematic Review.
Nagendran S, Alsamnan M, Strianese D, Malhotra R
Ophthalmic Plast Reconstr Surg 2020 Nov/Dec;36(6):540-544. doi: 10.1097/IOP.0000000000001621. PMID: 32205779
A systematic review of sinonasal oncocytomas and oncocytic carcinomas: Diagnosis, management, and technical considerations.
Hodzic Z, Rowan NR, Kashiwazaki R, Willson TJ, Wang EW, Lee SE
Int Forum Allergy Rhinol 2017 May;7(5):514-524. Epub 2017 Jan 16 doi: 10.1002/alr.21902. PMID: 28092140
Intermediate and long-term adverse effects of radioiodine therapy for differentiated thyroid carcinoma--a systematic review.
Clement SC, Peeters RP, Ronckers CM, Links TP, van den Heuvel-Eibrink MM, Nieveen van Dijkum EJ, van Rijn RR, van der Pal HJ, Neggers SJ, Kremer LC, van Eck-Smit BL, van Santen HM
Cancer Treat Rev 2015 Dec;41(10):925-34. Epub 2015 Sep 10 doi: 10.1016/j.ctrv.2015.09.001. PMID: 26421813
Nasolacrimal duct tumours in the era of endoscopic dacryocystorhinostomy: literature review.
Tanweer F, Mahkamova K, Harkness P
J Laryngol Otol 2013 Jul;127(7):670-5. Epub 2013 Jun 12 doi: 10.1017/S0022215113001163. PMID: 23756574

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...