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Lacrimal apparatus disorder

MedGen UID:
5994
•Concept ID:
C0022904
•
Disease or Syndrome
Synonym: Lacrimal apparatus disease
SNOMED CT: Lachrymal system disorders (31053003); Disorder of lacrimal system (31053003)
 
Monarch Initiative: MONDO:0001854

Definition

A non-neoplastic or neoplastic disorder that affects the lacrimal gland and/or the lacrimal drainage system. [from NCI]

Professional guidelines

PubMed

Dry Eye Disease: Prevalence, Assessment, and Management.
Rouen PA, White ML
Home Healthc Now 2018 Mar/Apr;36(2):74-83. doi: 10.1097/NHH.0000000000000652. PMID: 29498987
The Diagnosis and Treatment of Sjögren's Syndrome.
Stefanski AL, Tomiak C, Pleyer U, Dietrich T, Burmester GR, Dörner T
Dtsch Arztebl Int 2017 May 26;114(20):354-361. doi: 10.3238/arztebl.2017.0354. PMID: 28610655Free PMC Article
The pathophysiology, diagnosis, and treatment of dry eye disease.
Messmer EM
Dtsch Arztebl Int 2015 Jan 30;112(5):71-81; quiz 82. doi: 10.3238/arztebl.2015.0071. PMID: 25686388Free PMC Article

Recent clinical studies

Etiology

Repeated Lacrimal Gland Biopsies.
Kaushik M, Vahdani K, Neumann I, Magan T, Rose GE
Ophthalmic Plast Reconstr Surg 2024 Jul-Aug 01;40(4):440-444. Epub 2024 Feb 5 doi: 10.1097/IOP.0000000000002614. PMID: 38329425
Recurrent lacrimal gland pleomorphic adenoma.
Reilly S, Ellard R, O'Sullivan M, Khan R, Kennedy S
Orbit 2023 Dec;42(6):635-640. Epub 2022 May 12 doi: 10.1080/01676830.2022.2064515. PMID: 35546531
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Current treatment of lacrimal gland carcinoma.
Woo KI, Kim YD, Sa HS, Esmaeli B
Curr Opin Ophthalmol 2016 Sep;27(5):449-56. doi: 10.1097/ICU.0000000000000301. PMID: 27273588
Diagnostic criteria for IgG4-related ophthalmic disease.
Goto H, Takahira M, Azumi A; Japanese Study Group for IgG4-Related Ophthalmic Disease
Jpn J Ophthalmol 2015 Jan;59(1):1-7. Epub 2014 Nov 14 doi: 10.1007/s10384-014-0352-2. PMID: 25392273

Diagnosis

Repeated Lacrimal Gland Biopsies.
Kaushik M, Vahdani K, Neumann I, Magan T, Rose GE
Ophthalmic Plast Reconstr Surg 2024 Jul-Aug 01;40(4):440-444. Epub 2024 Feb 5 doi: 10.1097/IOP.0000000000002614. PMID: 38329425
Non-infectious Dacryoadenitis.
Singh S, Selva D
Surv Ophthalmol 2022 Mar-Apr;67(2):353-368. Epub 2021 May 31 doi: 10.1016/j.survophthal.2021.05.011. PMID: 34081929
Dacryops - A review.
Tanaboonyawat S, Idowu OO, Copperman TS, Vagefi MR, Kersten RC
Orbit 2020 Apr;39(2):128-134. Epub 2019 Sep 12 doi: 10.1080/01676830.2019.1608564. PMID: 31512543
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Dacryolithiasis: A Review.
Mishra K, Hu KY, Kamal S, Andron A, Della Rocca RC, Ali MJ, Nair AG
Ophthalmic Plast Reconstr Surg 2017 Mar/Apr;33(2):83-89. doi: 10.1097/IOP.0000000000000769. PMID: 27533513

Therapy

Dacryocystectomy: A fibrin glue-assisted subfascial excision.
Tong JY, Selva D
Indian J Ophthalmol 2023 May;71(5):2260-2262. doi: 10.4103/IJO.IJO_2667_22. PMID: 37202965Free PMC Article
Intense pulsed light (IPL) therapy for the treatment of meibomian gland dysfunction.
Cote S, Zhang AC, Ahmadzai V, Maleken A, Li C, Oppedisano J, Nair K, Busija L, Downie LE
Cochrane Database Syst Rev 2020 Mar 18;3(3):CD013559. doi: 10.1002/14651858.CD013559. PMID: 32182637Free PMC Article
Lymphoproliferative tumors involving the lacrimal drainage system: a major review.
Singh S, Ali MJ
Orbit 2020 Aug;39(4):276-284. Epub 2019 Jul 3 doi: 10.1080/01676830.2019.1634104. PMID: 31267826
Blepharoplasty complications.
Lelli GJ Jr, Lisman RD
Plast Reconstr Surg 2010 Mar;125(3):1007-17. doi: 10.1097/PRS.0b013e3181ce17e8. PMID: 20195127
The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007).
Ocul Surf 2007 Apr;5(2):75-92. doi: 10.1016/s1542-0124(12)70081-2. PMID: 17508116

Prognosis

Non-infectious Dacryoadenitis.
Singh S, Selva D
Surv Ophthalmol 2022 Mar-Apr;67(2):353-368. Epub 2021 May 31 doi: 10.1016/j.survophthal.2021.05.011. PMID: 34081929
Primary Malignant Epithelial Tumors of the Lacrimal Drainage System: A Major Review.
Singh S, Ali MJ
Orbit 2021 Jun;40(3):179-192. Epub 2020 Jun 8 doi: 10.1080/01676830.2020.1769684. PMID: 32506982
Lymphoproliferative tumors involving the lacrimal drainage system: a major review.
Singh S, Ali MJ
Orbit 2020 Aug;39(4):276-284. Epub 2019 Jul 3 doi: 10.1080/01676830.2019.1634104. PMID: 31267826
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Dacryolithiasis: A Review.
Mishra K, Hu KY, Kamal S, Andron A, Della Rocca RC, Ali MJ, Nair AG
Ophthalmic Plast Reconstr Surg 2017 Mar/Apr;33(2):83-89. doi: 10.1097/IOP.0000000000000769. PMID: 27533513

Clinical prediction guides

The 'tears' score: A tool for grading and monitoring epiphora.
Schulz CB, Malhotra R
Eur J Ophthalmol 2022 Jul;32(4):2108-2115. Epub 2022 May 29 doi: 10.1177/11206721221104550. PMID: 35635181
Bilateral lacrimal gland disease: clinical features and outcomes.
Huang S, Juniat V, Satchi K, Cohen LM, Davis G, Rootman DB, McNab A, Selva D
Eye (Lond) 2022 Nov;36(11):2163-2171. Epub 2021 Nov 1 doi: 10.1038/s41433-021-01819-0. PMID: 34725471Free PMC Article
One year in review 2018: Sjögren's syndrome.
Argyropoulou OD, Valentini E, Ferro F, Leone MC, Cafaro G, Bartoloni E, Baldini C
Clin Exp Rheumatol 2018 May-Jun;36 Suppl 112(3):14-26. Epub 2018 Jul 18 PMID: 30156536
IgG4-related orbital disease.
Flores Balverdi J, Baenas DF, Riscanevo NC, Sánchez AV, Figueroa Rosales R, Alvarellos A
Arch Soc Esp Oftalmol (Engl Ed) 2018 Oct;93(10):494-496. Epub 2018 Jun 1 doi: 10.1016/j.oftal.2018.04.003. PMID: 29866378
EULAR Sjogren's syndrome disease activity index: development of a consensus systemic disease activity index for primary Sjogren's syndrome.
Seror R, Ravaud P, Bowman SJ, Baron G, Tzioufas A, Theander E, Gottenberg JE, Bootsma H, Mariette X, Vitali C; EULAR Sjögren's Task Force
Ann Rheum Dis 2010 Jun;69(6):1103-9. Epub 2009 Jun 28 doi: 10.1136/ard.2009.110619. PMID: 19561361Free PMC Article

Recent systematic reviews

Oral Manifestations of Systemic Lupus Erythematosus: A Systematic Review.
García-Ríos P, Pecci-Lloret MP, Oñate-Sánchez RE
Int J Environ Res Public Health 2022 Sep 21;19(19) doi: 10.3390/ijerph191911910. PMID: 36231212Free PMC Article
Interventions for the Management of Computer Vision Syndrome: A Systematic Review and Meta-analysis.
Singh S, McGuinness MB, Anderson AJ, Downie LE
Ophthalmology 2022 Oct;129(10):1192-1215. Epub 2022 May 18 doi: 10.1016/j.ophtha.2022.05.009. PMID: 35597519
Metabolomics and lipidomics approaches in human tears: A systematic review.
Khanna RK, Catanese S, Emond P, Corcia P, Blasco H, Pisella PJ
Surv Ophthalmol 2022 Jul-Aug;67(4):1229-1243. Epub 2022 Jan 31 doi: 10.1016/j.survophthal.2022.01.010. PMID: 35093405
Efficacy and safety of topical and systemic medications: a systematic literature review informing the EULAR recommendations for the management of Sjögren's syndrome.
Brito-Zerón P, Retamozo S, Kostov B, Baldini C, Bootsma H, De Vita S, Dörner T, Gottenberg JE, Kruize AA, Mandl T, Ng WF, Seror R, Tzioufas AG, Vitali C, Bowman S, Mariette X, Ramos-Casals M
RMD Open 2019;5(2):e001064. Epub 2019 Oct 28 doi: 10.1136/rmdopen-2019-001064. PMID: 31749986Free PMC Article
The association between endometriosis and autoimmune diseases: a systematic review and meta-analysis.
Shigesi N, Kvaskoff M, Kirtley S, Feng Q, Fang H, Knight JC, Missmer SA, Rahmioglu N, Zondervan KT, Becker CM
Hum Reprod Update 2019 Jul 1;25(4):486-503. doi: 10.1093/humupd/dmz014. PMID: 31260048Free PMC Article

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