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Lacrimal Drainage System Neoplasm

MedGen UID:
738686
•Concept ID:
C1644176
•
Neoplastic Process
Synonyms: Neoplasm of lacrimal drainage system; Neoplasm of lacrimal duct
SNOMED CT: Neoplasm of lacrimal drainage system (419889000); Neoplasm of lacrimal duct (419889000)

Definition

A benign or malignant neoplasm that affects the lacrimal drainage system. [from NCI]

Professional guidelines

PubMed

Dacryoendoscopic Findings of Patients with Lacrimal Drainage Obstruction Associated with Cancer Treatment.
Kim Y, Lew H
Korean J Ophthalmol 2022 Dec;36(6):509-517. Epub 2022 Oct 11 doi: 10.3341/kjo.2022.0051. PMID: 36220641Free PMC Article
Ocular surface complications of local anticancer drugs for treatment of ocular tumors.
Moon J, Choi SH, Lee MJ, Jo DH, Park UC, Yoon SO, Woo SJ, Oh JY
Ocul Surf 2021 Jan;19:16-30. Epub 2020 Nov 22 doi: 10.1016/j.jtos.2020.11.006. PMID: 33238207
Clinical features and treatment outcomes of patients with tearing after chemotherapy.
Park J, Kim J, Baek S
Eye (Lond) 2019 May;33(5):746-753. Epub 2018 Dec 10 doi: 10.1038/s41433-018-0305-y. PMID: 30531801Free PMC Article

Recent clinical studies

Etiology

Blood-stained tears-a red flag for malignancy?
Kaushik M, Juniat V, Ezra DG, Verity DH, Uddin J, Timlin H
Eye (Lond) 2023 Jun;37(8):1711-1716. Epub 2022 Sep 10 doi: 10.1038/s41433-022-02224-x. PMID: 36088421Free PMC Article
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Carcinomas of the lacrimal drainage system.
Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675
Patency of the lacrimal drainage system in patients with a peripunctal tumour.
Ishikawa E, Sabundayo MS, Kono S, Kakizaki H, Takahashi Y
Orbit 2020 Apr;39(2):102-106. Epub 2019 Jun 6 doi: 10.1080/01676830.2019.1626446. PMID: 31169438
Tumors of the lacrimal drainage system.
Heindl LM, Jünemann AG, Kruse FE, Holbach LM
Orbit 2010 Oct;29(5):298-306. doi: 10.3109/01676830.2010.492887. PMID: 20958177

Diagnosis

Blood-stained tears-a red flag for malignancy?
Kaushik M, Juniat V, Ezra DG, Verity DH, Uddin J, Timlin H
Eye (Lond) 2023 Jun;37(8):1711-1716. Epub 2022 Sep 10 doi: 10.1038/s41433-022-02224-x. PMID: 36088421Free PMC Article
Melanoma of the lacrimal drainage system: A systematic review.
Vinciguerra A, Rampi A, Giordano Resti A, Barbieri D, Bussi M, Trimarchi M
Head Neck 2021 Jul;43(7):2240-2252. Epub 2021 Apr 12 doi: 10.1002/hed.26705. PMID: 33843111
Primary Malignant Epithelial Tumors of the Lacrimal Drainage System: A Major Review.
Singh S, Ali MJ
Orbit 2021 Jun;40(3):179-192. Epub 2020 Jun 8 doi: 10.1080/01676830.2020.1769684. PMID: 32506982
Carcinomas of the lacrimal drainage system.
Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675
Lymphoproliferative tumors involving the lacrimal drainage system: a major review.
Singh S, Ali MJ
Orbit 2020 Aug;39(4):276-284. Epub 2019 Jul 3 doi: 10.1080/01676830.2019.1634104. PMID: 31267826

Therapy

The Association Between Taxane Use and Lacrimal Disorders.
McGwin G Jr, Contorno T, Vicinanzo MG, Owsley C
Curr Eye Res 2023 Sep;48(9):873-877. Epub 2023 Jun 2 doi: 10.1080/02713683.2023.2219041. PMID: 37232564
Ocular surface complications of local anticancer drugs for treatment of ocular tumors.
Moon J, Choi SH, Lee MJ, Jo DH, Park UC, Yoon SO, Woo SJ, Oh JY
Ocul Surf 2021 Jan;19:16-30. Epub 2020 Nov 22 doi: 10.1016/j.jtos.2020.11.006. PMID: 33238207
Lymphoproliferative tumors involving the lacrimal drainage system: a major review.
Singh S, Ali MJ
Orbit 2020 Aug;39(4):276-284. Epub 2019 Jul 3 doi: 10.1080/01676830.2019.1634104. PMID: 31267826
Lacrimal drainage system stenosis associated with Trastuzumab emtansine (Kadcyla®, T-DM1) administration: a case report.
Kim CY, Kim N, Choung HK, In Khwarg S
BMC Cancer 2019 Aug 6;19(1):774. doi: 10.1186/s12885-019-5986-5. PMID: 31387552Free PMC Article
Postoncological lacrimal duct reconstruction: A practical classification system for reconstructive planning and short-term results of a case series.
van Burink MV, Rakhorst HA, van Couwelaar GM, Schmidbauer U
J Plast Reconstr Aesthet Surg 2018 Dec;71(12):1796-1803. Epub 2018 Aug 3 doi: 10.1016/j.bjps.2018.07.024. PMID: 30213744

Prognosis

Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Melanoma of the lacrimal drainage system: A systematic review.
Vinciguerra A, Rampi A, Giordano Resti A, Barbieri D, Bussi M, Trimarchi M
Head Neck 2021 Jul;43(7):2240-2252. Epub 2021 Apr 12 doi: 10.1002/hed.26705. PMID: 33843111
Primary Malignant Epithelial Tumors of the Lacrimal Drainage System: A Major Review.
Singh S, Ali MJ
Orbit 2021 Jun;40(3):179-192. Epub 2020 Jun 8 doi: 10.1080/01676830.2020.1769684. PMID: 32506982
Lymphoproliferative tumors involving the lacrimal drainage system: a major review.
Singh S, Ali MJ
Orbit 2020 Aug;39(4):276-284. Epub 2019 Jul 3 doi: 10.1080/01676830.2019.1634104. PMID: 31267826
Tumors of the lacrimal drainage system.
Heindl LM, Jünemann AG, Kruse FE, Holbach LM
Orbit 2010 Oct;29(5):298-306. doi: 10.3109/01676830.2010.492887. PMID: 20958177

Clinical prediction guides

Long-Term Outcome for Primary Papillomas of the Lacrimal Drainage System.
Vahdani K, Rose GE
Ophthalmic Plast Reconstr Surg 2024 Sep-Oct 01;40(5):538-543. Epub 2024 Feb 19 doi: 10.1097/IOP.0000000000002636. PMID: 38372630
Human papillomavirus-related neoplasia of the ocular adnexa.
Ramberg IMS
Acta Ophthalmol 2022 Oct;100 Suppl 272(Suppl 272):3-33. doi: 10.1111/aos.15244. PMID: 36203222Free PMC Article
Microdebridement of Intranasal Cysts Associated With Congenital Dacryocystoceles.
Magoon K, Landau Prat D, Guo M, Revere K, Katowitz WR
Ophthalmic Plast Reconstr Surg 2022 Jul-Aug 01;38(4):401-403. Epub 2022 Jul 5 doi: 10.1097/IOP.0000000000002140. PMID: 35170563
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Patency of the lacrimal drainage system in patients with a peripunctal tumour.
Ishikawa E, Sabundayo MS, Kono S, Kakizaki H, Takahashi Y
Orbit 2020 Apr;39(2):102-106. Epub 2019 Jun 6 doi: 10.1080/01676830.2019.1626446. PMID: 31169438

Recent systematic reviews

NK/T-cell Lymphoma With Orbital Involvement: A Case Report and Systematic Review of the Literature.
Dhodapkar RM, Spadaro JZ, Heng JS, Sinard JH, Lee YH, Habib LA, Pointdujour-Lim R
Ophthalmic Plast Reconstr Surg 2023 Jul-Aug 01;39(4):316-327. Epub 2023 Jan 24 doi: 10.1097/IOP.0000000000002317. PMID: 36692957
Holding back the tears: is there a role for marsupialisation?
Chiu SJ, Currie ZI, Tan JH
BMJ Open Ophthalmol 2022 Aug;7(1) doi: 10.1136/bmjophth-2022-000985. PMID: 36161857Free PMC Article
Melanoma of the lacrimal drainage system: A systematic review.
Vinciguerra A, Rampi A, Giordano Resti A, Barbieri D, Bussi M, Trimarchi M
Head Neck 2021 Jul;43(7):2240-2252. Epub 2021 Apr 12 doi: 10.1002/hed.26705. PMID: 33843111

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