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Abnormal uvea morphology

MedGen UID:
871348
•Concept ID:
C4025842
•
Anatomical Abnormality
Synonym: Abnormality of the uvea
 
HPO: HP:0000553

Definition

An abnormality of the uvea, the vascular layer of the eyeball. [from HPO]

Professional guidelines

PubMed

Diagnosis and treatment of microspherophakia.
Yu X, Chen W, Xu W
J Cataract Refract Surg 2020 Dec;46(12):1674-1679. doi: 10.1097/j.jcrs.0000000000000334. PMID: 32694307
Polypoidal choroidal vasculopathy: Pearls in diagnosis and management.
Anantharaman G, Sheth J, Bhende M, Narayanan R, Natarajan S, Rajendran A, Manayath G, Sen P, Biswas R, Banker A, Gupta C
Indian J Ophthalmol 2018 Jul;66(7):896-908. doi: 10.4103/ijo.IJO_1136_17. PMID: 29941728Free PMC Article
PLATEAU IRIS--DIAGNOSIS AND TREATMENT.
Stefan C, Iliescu DA, Batras M, Timaru CM, De Simone A
Rom J Ophthalmol 2015 Jan-Mar;59(1):14-8. PMID: 27373109Free PMC Article

Recent clinical studies

Etiology

Sildenafil in ophthalmology: An update.
Arora S, Surakiatchanukul T, Arora T, Cagini C, Lupidi M, Chhablani J
Surv Ophthalmol 2022 Mar-Apr;67(2):463-487. Epub 2021 Jun 25 doi: 10.1016/j.survophthal.2021.06.004. PMID: 34175342
Vascular abnormalities in uveitis.
Ebrahimiadib N, Maleki A, Fadakar K, Manhapra A, Ghassemi F, Foster CS
Surv Ophthalmol 2021 Jul-Aug;66(4):653-667. Epub 2021 Jan 5 doi: 10.1016/j.survophthal.2020.12.006. PMID: 33412171
Pachychoroid neovasculopathy.
Pang CE, Freund KB
Retina 2015 Jan;35(1):1-9. doi: 10.1097/IAE.0000000000000331. PMID: 25158945
Polypoidal choroidal vasculopathy.
Ciardella AP, Donsoff IM, Yannuzzi LA
Ophthalmol Clin North Am 2002 Dec;15(4):537-54. doi: 10.1016/s0896-1549(02)00053-6. PMID: 12515086
Trisomy 22.
Zellweger H, Ionasescu V, Simpson J
J Genet Hum 1975 Mar;23(1):65-75. PMID: 1165480

Diagnosis

Congenital Microcoria.
Jeeva-Patel T, Lutchman C, Margolin E
Ophthalmology 2021 Apr;128(4):586. doi: 10.1016/j.ophtha.2020.11.006. PMID: 33745527
Vascular abnormalities in uveitis.
Ebrahimiadib N, Maleki A, Fadakar K, Manhapra A, Ghassemi F, Foster CS
Surv Ophthalmol 2021 Jul-Aug;66(4):653-667. Epub 2021 Jan 5 doi: 10.1016/j.survophthal.2020.12.006. PMID: 33412171
The Pupil.
Bouffard MA
Continuum (Minneap Minn) 2019 Oct;25(5):1194-1214. doi: 10.1212/CON.0000000000000771. PMID: 31584534
Uveal melanoma.
Kashyap S, Meel R, Singh L, Singh M
Semin Diagn Pathol 2016 May;33(3):141-7. Epub 2016 Mar 10 doi: 10.1053/j.semdp.2015.10.005. PMID: 26972224
PLATEAU IRIS--DIAGNOSIS AND TREATMENT.
Stefan C, Iliescu DA, Batras M, Timaru CM, De Simone A
Rom J Ophthalmol 2015 Jan-Mar;59(1):14-8. PMID: 27373109Free PMC Article

Therapy

A systematic approach to the management of microspherophakia.
Venkataraman P, Haripriya A, Mohan N, Rajendran A
Indian J Ophthalmol 2022 Jul;70(7):2262-2271. doi: 10.4103/ijo.IJO_2888_21. PMID: 35791105Free PMC Article
Sildenafil in ophthalmology: An update.
Arora S, Surakiatchanukul T, Arora T, Cagini C, Lupidi M, Chhablani J
Surv Ophthalmol 2022 Mar-Apr;67(2):463-487. Epub 2021 Jun 25 doi: 10.1016/j.survophthal.2021.06.004. PMID: 34175342
Current management strategy of polypoidal choroidal vasculopathy.
Ho CPS, Lai TYY
Indian J Ophthalmol 2018 Dec;66(12):1727-1735. doi: 10.4103/ijo.IJO_975_18. PMID: 30451173Free PMC Article
Polypoidal choroidal vasculopathy.
Ciardella AP, Donsoff IM, Yannuzzi LA
Ophthalmol Clin North Am 2002 Dec;15(4):537-54. doi: 10.1016/s0896-1549(02)00053-6. PMID: 12515086
Malignant glaucoma.
Simmons RJ
Br J Ophthalmol 1972 Mar;56(3):263-72. doi: 10.1136/bjo.56.3.263. PMID: 5032764Free PMC Article

Prognosis

Punctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches.
Kalogeropoulos D, Rahman N, Afshar F, Hall N, Lotery AJ
Prog Retin Eye Res 2024 Mar;99:101235. Epub 2024 Jan 3 doi: 10.1016/j.preteyeres.2023.101235. PMID: 38181975
Primary congenital glaucoma: An iridotrabeculodysgenesis?
Sihota R, Mahalingam K, Maurya AK, Sharma A, Bukke AN, Dada T
Indian J Ophthalmol 2024 Mar 1;72(3):328-334. Epub 2023 Dec 15 doi: 10.4103/IJO.IJO_370_23. PMID: 38099353Free PMC Article
Disorders of vision in multiple sclerosis.
Dhanapalaratnam R, Markoulli M, Krishnan AV
Clin Exp Optom 2022 Jan;105(1):3-12. Epub 2021 Aug 4 doi: 10.1080/08164622.2021.1947745. PMID: 34348598
Uveal melanoma.
Kashyap S, Meel R, Singh L, Singh M
Semin Diagn Pathol 2016 May;33(3):141-7. Epub 2016 Mar 10 doi: 10.1053/j.semdp.2015.10.005. PMID: 26972224
Polypoidal choroidal vasculopathy.
Ciardella AP, Donsoff IM, Huang SJ, Costa DL, Yannuzzi LA
Surv Ophthalmol 2004 Jan-Feb;49(1):25-37. doi: 10.1016/j.survophthal.2003.10.007. PMID: 14711438

Clinical prediction guides

Punctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches.
Kalogeropoulos D, Rahman N, Afshar F, Hall N, Lotery AJ
Prog Retin Eye Res 2024 Mar;99:101235. Epub 2024 Jan 3 doi: 10.1016/j.preteyeres.2023.101235. PMID: 38181975
Disorders of vision in multiple sclerosis.
Dhanapalaratnam R, Markoulli M, Krishnan AV
Clin Exp Optom 2022 Jan;105(1):3-12. Epub 2021 Aug 4 doi: 10.1080/08164622.2021.1947745. PMID: 34348598
Multimodal imaging in pachychoroid spectrum.
Safi H, Ahmadieh H, Hassanpour K, Safi S
Surv Ophthalmol 2022 Mar-Apr;67(2):579-590. Epub 2021 Jul 29 doi: 10.1016/j.survophthal.2021.07.004. PMID: 34331955
Sildenafil in ophthalmology: An update.
Arora S, Surakiatchanukul T, Arora T, Cagini C, Lupidi M, Chhablani J
Surv Ophthalmol 2022 Mar-Apr;67(2):463-487. Epub 2021 Jun 25 doi: 10.1016/j.survophthal.2021.06.004. PMID: 34175342
Pachychoroid neovasculopathy.
Pang CE, Freund KB
Retina 2015 Jan;35(1):1-9. doi: 10.1097/IAE.0000000000000331. PMID: 25158945

Recent systematic reviews

Diagnosis and treatment of microspherophakia.
Yu X, Chen W, Xu W
J Cataract Refract Surg 2020 Dec;46(12):1674-1679. doi: 10.1097/j.jcrs.0000000000000334. PMID: 32694307
Spectrum of pachychoroid diseases.
Akkaya S
Int Ophthalmol 2018 Oct;38(5):2239-2246. Epub 2017 Aug 1 doi: 10.1007/s10792-017-0666-4. PMID: 28766279
Choroidal Thickness and Open-Angle Glaucoma: A Meta-Analysis and Systematic Review.
Zhang Z, Yu M, Wang F, Dai Y, Wu Z
J Glaucoma 2016 May;25(5):e446-54. doi: 10.1097/IJG.0000000000000275. PMID: 25943737
PLATEAU IRIS--DIAGNOSIS AND TREATMENT.
Stefan C, Iliescu DA, Batras M, Timaru CM, De Simone A
Rom J Ophthalmol 2015 Jan-Mar;59(1):14-8. PMID: 27373109Free PMC Article
Ocular Manifestations and Therapeutic Options in Patients with Familial Amyloid Polyneuropathy: A Systematic Review.
Martins AC, Rosa AM, Costa E, Tavares C, Quadrado MJ, Murta JN
Biomed Res Int 2015;2015:282405. Epub 2015 Oct 19 doi: 10.1155/2015/282405. PMID: 26558262Free PMC Article

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