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The crystal structue of PDE10A complexed with 2d[HYDROLASE]
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The crystal structue of PDE10A complexed with 1i[HYDROLASE]
Crystal structure of PDE10A in complex with a triazolopyrimidine inhibitor[HYDROLASE]
Crystal structure of PDE10 in complex with inhibitor 2b[HYDROLASE/INHIBITOR]
Crystal structure of PDE10 in complex with inhibitor AF-399/14387019[HYDROLASE/INHIBITOR]
Crystal structure of PDE10A in complex with 7-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidine[HYDROLASE/HYDROLASE INHIBITOR]
Crystal structure of PDE10A in complex with 2-methyl-5-[2-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)et hyl]pyrazolo[1,5-a]pyrimidin-7-ol[HYDROLASE/HYDROLASE INHIBITOR]
Crystal structure of human PDE10A in complex with inhibitor 16d[Hydrolase/Hydrolase Inhibitor]
Pde10a With Imidazopyrazine Inhibitor[HydrolaseHYDROLASE INHIBITOR, EC: 3.1.4.17| 3.1.4.35]
Human Pde10a In Complex With 3-(2-phenylpyrazol-3-yl)-1-[3- (trifluoromethoxy)phenyl]pyridazin-4-one[Hydrolase, EC: 3.1.4.17| 3.1.4.35]
Human Pde10a, 6-chloro-5,8-dimethyl-2-[2-(2-methyl-5-pyrrolidin-1-yl- 2h-[1,2,4]triazol-3-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyridine, 2.20a, H3, Rfree=23.5%[Hydrolase, EC: 3.1.4.17| 3.1.4.35]
Human Pde10a, 8-ethyl-5-methyl-2-[2-(2-methyl-5-pyrrolidin-1-yl-1,2,4- Triazol-3-yl)ethyl]-[1,2,4]triazolo[1,5-c]pyrimidine, 2.03a, H3, Rfree=22.7%[Hydrolase, EC: 3.1.4.17| 3.1.4.35]
Human Pde10a In Complex With 3-(2-chloro-5-phenyl-3h-imidazol-4-yl)-1- (3-trifluoromethoxy-phenyl)-1h-pyridazin-4-one At 2.30a[Hydrolase, EC: 3.1.4.17| 3.1.4.35]
Human Pde10a In Complex With 1-(4-chloro-phenyl)-3-methyl-1h-thieno[2, 3-c]pyrazole-5-carboxylic Acid (tetrahydro-furan-2-ylmethyl)-amide At 2.2a[Hydrolase, EC: 3.1.4.17| 3.1.4.35]
PDE10 complexed with N-[(1-methylpyrazol-4-yl)methyl]-5-[[(1S,2S)-2-(2-pyridyl)cyclopropyl]methoxy]pyrazolo[1,5-a]pyrimidin-7-amine[HYDROLASE/HYDROLASE INHIBITOR]
Pde10 Complexed With 5-chloro-n-[(2,4-dimethylthiazol-5-yl) Methyl]pyrazolo[1,5-a]pyrimidin-7-amine[HydrolaseHYDROLASE INHIBITOR, EC: 3.1.4.17| 3.1.4.35]
PDE10 complexed with6-chloro-N-[(2,4-dimethylthiazol-5-yl)methyl]-5-methyl-2-[2-(2-pyridyl)ethoxy]pyrimidin-4-amine[hydrolase/hydrolase inhibitor]
Crystal structure of the catalytic domain of PDE10A complexed with highly potent and brain-penetrant PDE10A Inhibitor with 2-oxindole scaffold[HYDROLASE/HYDROLASE INHIBITOR]
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