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BAP1 loss triggers DNA methylomic repatterning in highly aggressive Class 2 uveal melanomas [MethylationEPIC]
PubMed Full text in PMC Similar studies Analyze with GEO2R
BAP1 loss triggers DNA methylomic repatterning in highly aggressive Class 2 uveal melanomas
BAP1 loss triggers DNA methylomic repatterning in highly aggressive Class 2 uveal melanomas [RNA-Seq]
PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector
BAP1 loss triggers DNA methylomic repatterning in highly aggressive Class 2 uveal melanomas [BeadChip 450K]
RNA-seq analysis of BAP1-depleted uveal melanoma cells
Gene expression analysis of uveal melanoma Class 1 tumors with and without metastasis
Gene expression changes resulting from the stable loss of BAP1 in uveal melanoma cell lines
BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors
In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations
PubMed Similar studies Analyze with GEO2R
Global expression analysis of BAP1 knockdown in transfected 92.1 cells
Expression Data from Uveal Melanoma patient-derived xenograft and tumor of origin
Integrated differential DNA methylation and gene expression of formalin-fixed paraffin-embedded uveal melanoma specimens identifies genes associated with early metastasis and poor prognosis
Gene expression data from formalin-fixed paraffin-embedded (FFPE) human uveal melanoma tumors; subset early metastasis vs subset no metastasis
llumina 450k array was used to identify DNA methylation data from formalin-fixed paraffine-embedded (FFPE) human uveal melanoma correlated to gene expression, metastasis and poor prognosis
Transcriptomic analysis of BAP1 negative primary and metastatic uveal melanoma tumors
Loss of Bap1 in Xenopus laevis embryos
PubMed Full text in PMC Similar studies
Loss of Bap1 leads to an increased global methylation and decrease in H3K27AC enhancer marks around key lineage commitment genes in Xenopus laevis embryos [ChIP-seq]
PubMed Full text in PMC Similar studies SRA Run Selector
Bap1 loss leads to decreased expression of lineage specific commitment genes, and increased expression of pluripotency genes [RNA-seq]
RNA-seq analysis of BAP1 mutant and wild-type uveal melanoma cell lines
Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s.
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