NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE65978 Query DataSets for GSE65978
Status Public on Feb 09, 2017
Title microRNA data from high-fat diet fed mice with and without exercise
Platform organism synthetic construct
Sample organism Mus musculus
Experiment type Non-coding RNA profiling by array
Summary Non-alcoholic fatty liver disease (NAFLD) is associated with obesity and lifestyle. Exercise is known to be beneficial for NAFLD treatment. Recent studies have shown the critical involvement of microRNA in NAFLD. However, it is unclear whether exercise could prevent NAFLD via miRNA targeting.
We used microarrays to examine microRNA profiles in high-fat diet fed mice with and without exercise in comparison to normal diet fed mice.
 
Overall design Mouse livers from normal diet fed mice (group C, n=5), high-fat diet fed mice without exercise (group HF, n=5), and high-fat diet fed mice with exercise (groupe HE, n=5) were used for RNA extraction and hybridization on Affymetrix miRNA 3.0.
 
Contributor(s) Xiao J, Bei Y
Citation(s) 26648452
Submission date Feb 17, 2015
Last update date Jul 27, 2018
Contact name Yihua Bei
E-mail(s) beiyh36@yahoo.fr
Phone +86 13816265303
Organization name Shanghai University
Department School of Life Science
Lab Regeneration Lab
Street address 133 Nanchen Road
City Shanghai
ZIP/Postal code 200444
Country China
 
Platforms (1)
GPL16384 [miRNA-3] Affymetrix Multispecies miRNA-3 Array
Samples (15)
GSM1611895 Liver_Normal diet_rep1
GSM1611896 Liver_Normal diet_rep2
GSM1611897 Liver_Normal diet_rep3
Relations
BioProject PRJNA275623

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE65978_RAW.tar 33.4 Mb (http)(custom) TAR (of CEL)
GSE65978_fold_change.txt.gz 243.5 Kb (ftp)(http) TXT
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap