U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ischemic disease

MedGen UID:
5899
•Concept ID:
C0022116
•
Pathologic Function
Synonyms: Ischemia; Ischemias
SNOMED CT: Ischemia (52674009)
 
Monarch Initiative: MONDO:0005053

Definition

Lack of blood supply to an area of the body, resulting in impairment of tissue oxygenation. [from NCI]

Professional guidelines

PubMed

Insights into the Explicit Protective Activity of Herbals in Management of Neurodegenerative and Cerebrovascular Disorders.
Behl T, Makkar R, Sehgal A, Sharma N, Singh S, Albratty M, Najmi A, Meraya AM, Bungau SG
Molecules 2022 Aug 4;27(15) doi: 10.3390/molecules27154970. PMID: 35956919Free PMC Article
Evaluation and Management of Kidney Calculi.
Shadman A, Bastani B
Iran J Kidney Dis 2017 Nov;11(6):395-407. PMID: 29190598
Evidence for maximal treatment of atherosclerosis: drastic reduction of cholesterol and fibrinogen restores vascular homeostasis.
Jaeger BR
Ther Apher 2001 Jun;5(3):207-11. PMID: 11467757

Recent clinical studies

Etiology

Is Alzheimer's Disease Risk Modifiable?
Serrano-Pozo A, Growdon JH
J Alzheimers Dis 2019;67(3):795-819. doi: 10.3233/JAD181028. PMID: 30776012Free PMC Article
Migraine and the risk for stroke and cardiovascular disease.
Sacco S, Kurth T
Curr Cardiol Rep 2014 Sep;16(9):524. doi: 10.1007/s11886-014-0524-1. PMID: 25059466
Concise review: Circulating endothelial progenitor cells for vascular medicine.
Asahara T, Kawamoto A, Masuda H
Stem Cells 2011 Nov;29(11):1650-5. doi: 10.1002/stem.745. PMID: 21948649
Homocysteine and oxidative stress.
Perna AF, Ingrosso D, De Santo NG
Amino Acids 2003 Dec;25(3-4):409-17. Epub 2003 Jul 31 doi: 10.1007/s00726-003-0026-8. PMID: 14661100
Pediatric neurosonography.
Grant EG, White EM
J Child Neurol 1986 Oct;1(4):319-37. doi: 10.1177/088307388600100403. PMID: 3298401

Diagnosis

Vascular Myelopathies.
Jadhav AP
Continuum (Minneap Minn) 2024 Feb 1;30(1):160-179. doi: 10.1212/CON.0000000000001378. PMID: 38330477
Inherited platelet diseases with normal platelet count: phenotypes, genotypes and diagnostic strategy.
Nurden P, Stritt S, Favier R, Nurden AT
Haematologica 2021 Feb 1;106(2):337-350. doi: 10.3324/haematol.2020.248153. [Epub ahead of print] PMID: 33147934Free PMC Article
Hypoxia and ischemia-reperfusion: a BiK contribution?
Tano JY, Gollasch M
Am J Physiol Heart Circ Physiol 2014 Sep 15;307(6):H811-7. Epub 2014 Jul 11 doi: 10.1152/ajpheart.00319.2014. PMID: 25015960
Ischaemic colitis--review.
Dimitrijević I, Micev M, Saranović Dj, Marković V, Petrović J, Antić S, Sekulić A, Krivokapić Z
Acta Chir Iugosl 2008;55(3):89-95. doi: 10.2298/aci0803089d. PMID: 19069699
Pediatric neurosonography.
Grant EG, White EM
J Child Neurol 1986 Oct;1(4):319-37. doi: 10.1177/088307388600100403. PMID: 3298401

Therapy

Protective Functions of Reactive Astrocytes Following Central Nervous System Insult.
Linnerbauer M, Rothhammer V
Front Immunol 2020;11:573256. Epub 2020 Sep 30 doi: 10.3389/fimmu.2020.573256. PMID: 33117368Free PMC Article
Panretinal Photocoagulation: A Review of Complications.
Reddy SV, Husain D
Semin Ophthalmol 2018;33(1):83-88. Epub 2017 Nov 27 doi: 10.1080/08820538.2017.1353820. PMID: 29172937
Nitric Oxide-Releasing Biomaterials for Biomedical Applications.
Zhou X, Zhang J, Feng G, Shen J, Kong D, Zhao Q
Curr Med Chem 2016;23(24):2579-2601. doi: 10.2174/0929867323666160729104647. PMID: 27480214
Therapeutic angiogenesis.
Vartanian SM, Sarkar R
Vasc Endovascular Surg 2007 Jun-Jul;41(3):173-85. doi: 10.1177/1538574407302849. PMID: 17595382
Heart transplantation.
Goldstein JP, Narine K, Wellens F, De Geest R, Deloof T, Coddens J, Gooris T, Vanermen H
Acta Chir Belg 1991 Jan-Feb;91(1):34-7. PMID: 2068879

Prognosis

Retinal degenerative and hypoxic ischemic disease.
Fulton AB, Akula JD, Mocko JA, Hansen RM, Benador IY, Beck SC, Fahl E, Seeliger MW, Moskowitz A, Harris ME
Doc Ophthalmol 2009 Feb;118(1):55-61. Epub 2008 May 16 doi: 10.1007/s10633-008-9127-8. PMID: 18483822Free PMC Article
Diagnostic efficacy of SonoVue.
Bokor D
Am J Cardiol 2000 Aug 17;86(4A):19G-24G. doi: 10.1016/s0002-9149(00)00985-1. PMID: 10997347
Quantitative stress echocardiography.
Shapiro SM, Ginzton LE
Echocardiography 1992 Jan;9(1):85-96. doi: 10.1111/j.1540-8175.1992.tb00444.x. PMID: 10149874
Pediatric neurosonography.
Grant EG, White EM
J Child Neurol 1986 Oct;1(4):319-37. doi: 10.1177/088307388600100403. PMID: 3298401
Tibial artery bypass.
Stephen M, Loewenthal J, Little JM, May J, Sheil R
Arch Surg 1976 Mar;111(3):235-8. doi: 10.1001/archsurg.1976.01360210029005. PMID: 1259559

Clinical prediction guides

Quantitative analysis and clinical application of iris circulation in ischemic retinal disease.
Jia Y, Xue W, Tong X, Wang Y, Cui L, Zou H
BMC Ophthalmol 2021 Nov 15;21(1):393. doi: 10.1186/s12886-021-02165-1. PMID: 34781913Free PMC Article
Distributed vasculogenesis from modular agarose-hydroxyapatite-fibrinogen microbeads.
Rioja AY, Daley ELH, Habif JC, Putnam AJ, Stegemann JP
Acta Biomater 2017 Jun;55:144-152. Epub 2017 Mar 29 doi: 10.1016/j.actbio.2017.03.050. PMID: 28365482Free PMC Article
How significant is the association between metabolic syndrome and prevalence of colorectal neoplasia?
Suchanek S, Grega T, Ngo O, Vojtechova G, Majek O, Minarikova P, Brogyuk N, Bunganic B, Seifert B, Dusek L, Zavoral M
World J Gastroenterol 2016 Sep 28;22(36):8103-11. doi: 10.3748/wjg.v22.i36.8103. PMID: 27688652Free PMC Article
Retinal degenerative and hypoxic ischemic disease.
Fulton AB, Akula JD, Mocko JA, Hansen RM, Benador IY, Beck SC, Fahl E, Seeliger MW, Moskowitz A, Harris ME
Doc Ophthalmol 2009 Feb;118(1):55-61. Epub 2008 May 16 doi: 10.1007/s10633-008-9127-8. PMID: 18483822Free PMC Article
Diagnostic efficacy of SonoVue.
Bokor D
Am J Cardiol 2000 Aug 17;86(4A):19G-24G. doi: 10.1016/s0002-9149(00)00985-1. PMID: 10997347

Recent systematic reviews

Comparative performance analysis of interventional devices for the treatment of ischemic disease in below-the-knee lesions: a systematic review and meta-analysis.
Matsuoka EK, Hasebe T, Ishii R, Miyazaki N, Soejima K, Iwasaki K
Cardiovasc Interv Ther 2022 Jan;37(1):145-157. Epub 2021 Feb 6 doi: 10.1007/s12928-021-00758-7. PMID: 33547627Free PMC Article
Outcomes of percutaneous temporary biventricular mechanical support: a systematic review.
Weber MP, O'Malley TJ, Choi JH, Maynes EJ, Prochno KW, Austin MA, Wood CT, Patel S, Morris RJ, Massey HT, Tchantchaleishvili V
Heart Fail Rev 2022 May;27(3):879-890. doi: 10.1007/s10741-020-09971-7. PMID: 32458216
Evaluation of the diagnostic value of multi-slice spiral CT in acute mesenteric ischemic diseases: a meta-analysis of randomized controlled trials.
Yang H, Wang BL
Eur Rev Med Pharmacol Sci 2019 Dec;23(23):10218-10225. doi: 10.26355/eurrev_201912_19657. PMID: 31841175
Carotid Plaque Positron Emission Tomography Imaging and Cerebral Ischemic Disease.
Chaker S, Al-Dasuqi K, Baradaran H, Demetres M, Delgado D, Nehmeh S, Osborne JR, Christos PJ, Kamel H, Gupta A
Stroke 2019 Aug;50(8):2072-2079. Epub 2019 Jul 5 doi: 10.1161/STROKEAHA.118.023987. PMID: 31272325Free PMC Article
White Matter Diffusion Abnormalities in Carotid Artery Disease: A Systematic Review and Meta-Analysis.
Baradaran H, Mtui EE, Richardson JE, Delgado D, Dunning A, Marshall RS, Sanelli PC, Gupta A
J Neuroimaging 2016 Sep;26(5):481-8. Epub 2016 Apr 15 doi: 10.1111/jon.12347. PMID: 27079165

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...