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Pharyngeal Carcinoma

MedGen UID:
148183
•Concept ID:
C0747548
•
Neoplastic Process
Synonyms: Cancer of Pharynx; Cancer of the Pharynx; Carcinoma of Pharynx; Carcinoma of the Pharynx; Pharyngeal Cancer; Pharynx Carcinoma

Definition

Carcinoma, predominantly squamous cell, arising from the epithelial cells of the pharynx. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPharyngeal Carcinoma

Professional guidelines

PubMed

Outcomes of Endoscopic Submucosal Dissection for Treatment of Superficial Pharyngeal Cancers: Systematic Review and Meta-Analysis.
Kamal F, Khan MA, Lee-Smith W, Sharma S, Imam Z, Jowhar D, Petryna E, Esswein J, Acharya A, Aziz M, Farooq U, Zafar U, Mcdonough S, Adler DG
Dig Dis Sci 2022 Aug;67(8):3518-3528. Epub 2021 Sep 9 doi: 10.1007/s10620-021-07225-6. PMID: 34505257
Recommendations for the diagnosis of human papilloma virus (HPV) high and low risk in the prevention and treatment of diseases of the oral cavity, pharynx and larynx. Guide of experts PTORL and KIDL.
Wierzbicka M, Józefiak A, Szydłowski J, Marszałek A, Stankiewicz C, Hassman-Poznańska E, Osuch-Wójcikiewicz E, Składzień J, Klatka J, Pietruszewska W, Puacz E, Szyfter K, Szyfter W
Otolaryngol Pol 2013 May-Jun;67(3):113-34. Epub 2013 Jan 11 doi: 10.1016/j.otpol.2013.01.003. PMID: 23719268
Transoral robotic surgery: role in the management of upper aerodigestive tract tumors.
Genden EM, O'Malley BW Jr, Weinstein GS, Stucken CL, Selber JC, Rinaldo A, Hockstein NG, Ozer E, Mallet Y, Satava RM, Moore EJ, Silver CE, Ferlito A
Head Neck 2012 Jun;34(6):886-93. Epub 2011 Aug 24 doi: 10.1002/hed.21752. PMID: 22610591

Recent clinical studies

Therapy

Assessment of the In Vitro Cytotoxic Profile of Two Broad-Spectrum Antibiotics-Tetracycline and Ampicillin-On Pharyngeal Carcinoma Cells.
Pancu DF, Racea RC, Macasoi I, Sarau CA, Pinzaru I, Poenaru M, Rusu LC, Dehelean CA, Dinu S
Medicina (Kaunas) 2022 Sep 16;58(9) doi: 10.3390/medicina58091289. PMID: 36143966Free PMC Article
Outcomes of Endoscopic Submucosal Dissection for Treatment of Superficial Pharyngeal Cancers: Systematic Review and Meta-Analysis.
Kamal F, Khan MA, Lee-Smith W, Sharma S, Imam Z, Jowhar D, Petryna E, Esswein J, Acharya A, Aziz M, Farooq U, Zafar U, Mcdonough S, Adler DG
Dig Dis Sci 2022 Aug;67(8):3518-3528. Epub 2021 Sep 9 doi: 10.1007/s10620-021-07225-6. PMID: 34505257
Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis.
Zhang W, Geng T, Han W, Dou H
Med Sci Monit 2014 Nov 3;20:2142-50. doi: 10.12659/MSM.892333. PMID: 25363316Free PMC Article
Gastroesophageal reflux and carcinoma of larynx or pharynx: a meta-analysis.
Zhang D, Zhou J, Chen B, Zhou L, Tao L
Acta Otolaryngol 2014 Oct;134(10):982-9. Epub 2014 Aug 18 doi: 10.3109/00016489.2014.927592. PMID: 25131391
Knowledge and perceptions regarding oral and pharyngeal carcinoma among adult dental patients.
Park JH, Slack-Smith L, Smith A, Frydrych AM, O'Ferrall I, Bulsara M
Aust Dent J 2011 Sep;56(3):284-9. Epub 2011 Aug 11 doi: 10.1111/j.1834-7819.2011.01342.x. PMID: 21884144

Prognosis

T52 attenuates oncogenic STAT3 signaling and suppresses osteosarcoma.
Tian L, Li C, Xiang L, Zeng J, Chen S, Guo W, Chen S, Wang Y, He X, Su P, Xu C
Phytomedicine 2023 Jun;114:154799. Epub 2023 Apr 3 doi: 10.1016/j.phymed.2023.154799. PMID: 37058945
WTAP-mediated m(6)A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis.
Li ZX, Zheng ZQ, Yang PY, Lin L, Zhou GQ, Lv JW, Zhang LL, Chen F, Li YQ, Wu CF, Li F, Ma J, Liu N, Sun Y
Cell Death Differ 2022 Jun;29(6):1137-1151. Epub 2022 Jan 8 doi: 10.1038/s41418-021-00905-w. PMID: 34999731Free PMC Article
Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis.
Zhang W, Geng T, Han W, Dou H
Med Sci Monit 2014 Nov 3;20:2142-50. doi: 10.12659/MSM.892333. PMID: 25363316Free PMC Article
Gastroesophageal reflux and carcinoma of larynx or pharynx: a meta-analysis.
Zhang D, Zhou J, Chen B, Zhou L, Tao L
Acta Otolaryngol 2014 Oct;134(10):982-9. Epub 2014 Aug 18 doi: 10.3109/00016489.2014.927592. PMID: 25131391
Subtotal laryngectomy.
Pearson BW
Laryngoscope 1981 Nov;91(11):1904-12. doi: 10.1288/00005537-198111000-00016. PMID: 7300541

Clinical prediction guides

T52 attenuates oncogenic STAT3 signaling and suppresses osteosarcoma.
Tian L, Li C, Xiang L, Zeng J, Chen S, Guo W, Chen S, Wang Y, He X, Su P, Xu C
Phytomedicine 2023 Jun;114:154799. Epub 2023 Apr 3 doi: 10.1016/j.phymed.2023.154799. PMID: 37058945
Determining Invasion Depth in Superficial Pharyngeal Carcinoma by Transoral Ultrasonography.
Yumii K, Ueda T, Urabe Y, Fukuhara M, Chikuie N, Taruya T, Kono T, Hamamoto T, Hattori M, Takumida M, Ishino T, Takeno S
Laryngoscope 2023 Sep;133(9):2192-2197. Epub 2022 Nov 28 doi: 10.1002/lary.30483. PMID: 36440626
Assessment of the In Vitro Cytotoxic Profile of Two Broad-Spectrum Antibiotics-Tetracycline and Ampicillin-On Pharyngeal Carcinoma Cells.
Pancu DF, Racea RC, Macasoi I, Sarau CA, Pinzaru I, Poenaru M, Rusu LC, Dehelean CA, Dinu S
Medicina (Kaunas) 2022 Sep 16;58(9) doi: 10.3390/medicina58091289. PMID: 36143966Free PMC Article
Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis.
Zhang W, Geng T, Han W, Dou H
Med Sci Monit 2014 Nov 3;20:2142-50. doi: 10.12659/MSM.892333. PMID: 25363316Free PMC Article
Trends in incidence of oral and pharyngeal carcinoma in Florida: 1981-2008.
McGorray SP, Guo Y, Logan H
J Public Health Dent 2012 Winter;72(1):68-74. Epub 2011 Sep 19 doi: 10.1111/j.1752-7325.2011.00285.x. PMID: 22316319Free PMC Article

Recent systematic reviews

Outcomes of Endoscopic Submucosal Dissection for Treatment of Superficial Pharyngeal Cancers: Systematic Review and Meta-Analysis.
Kamal F, Khan MA, Lee-Smith W, Sharma S, Imam Z, Jowhar D, Petryna E, Esswein J, Acharya A, Aziz M, Farooq U, Zafar U, Mcdonough S, Adler DG
Dig Dis Sci 2022 Aug;67(8):3518-3528. Epub 2021 Sep 9 doi: 10.1007/s10620-021-07225-6. PMID: 34505257
Gastroesophageal reflux and carcinoma of larynx or pharynx: a meta-analysis.
Zhang D, Zhou J, Chen B, Zhou L, Tao L
Acta Otolaryngol 2014 Oct;134(10):982-9. Epub 2014 Aug 18 doi: 10.3109/00016489.2014.927592. PMID: 25131391

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