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Immune system disorder

MedGen UID:
5759
•Concept ID:
C0021053
•
Disease or Syndrome
Synonym: Immune system disease
SNOMED CT: Immunity disorders (41266007); Disorder of immune system (41266007)
 
Monarch Initiative: MONDO:0005046

Definition

A disorder resulting from an abnormality in the immune system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVImmune system disorder

Professional guidelines

PubMed

International consensus statement on allergy and rhinology: Allergic rhinitis - 2023.
Wise SK, Damask C, Roland LT, Ebert C, Levy JM, Lin S, Luong A, Rodriguez K, Sedaghat AR, Toskala E, Villwock J, Abdullah B, Akdis C, Alt JA, Ansotegui IJ, Azar A, Baroody F, Benninger MS, Bernstein J, Brook C, Campbell R, Casale T, Chaaban MR, Chew FT, Chambliss J, Cianferoni A, Custovic A, Davis EM, DelGaudio JM, Ellis AK, Flanagan C, Fokkens WJ, Franzese C, Greenhawt M, Gill A, Halderman A, Hohlfeld JM, Incorvaia C, Joe SA, Joshi S, Kuruvilla ME, Kim J, Klein AM, Krouse HJ, Kuan EC, Lang D, Larenas-Linnemann D, Laury AM, Lechner M, Lee SE, Lee VS, Loftus P, Marcus S, Marzouk H, Mattos J, McCoul E, Melen E, Mims JW, Mullol J, Nayak JV, Oppenheimer J, Orlandi RR, Phillips K, Platt M, Ramanathan M Jr, Raymond M, Rhee CS, Reitsma S, Ryan M, Sastre J, Schlosser RJ, Schuman TA, Shaker MS, Sheikh A, Smith KA, Soyka MB, Takashima M, Tang M, Tantilipikorn P, Taw MB, Tversky J, Tyler MA, Veling MC, Wallace D, Wang Y, White A, Zhang L
Int Forum Allergy Rhinol 2023 Apr;13(4):293-859. Epub 2023 Mar 6 doi: 10.1002/alr.23090. PMID: 36878860
Hashimoto thyroiditis: clinical and diagnostic criteria.
Caturegli P, De Remigis A, Rose NR
Autoimmun Rev 2014 Apr-May;13(4-5):391-7. Epub 2014 Jan 13 doi: 10.1016/j.autrev.2014.01.007. PMID: 24434360
International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).
Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RH, DE Groot PG, Koike T, Meroni PL, Reber G, Shoenfeld Y, Tincani A, Vlachoyiannopoulos PG, Krilis SA
J Thromb Haemost 2006 Feb;4(2):295-306. doi: 10.1111/j.1538-7836.2006.01753.x. PMID: 16420554

Recent clinical studies

Etiology

Assessing the causal relationship between immune cell traits and depression by Mendelian randomization analysis.
Xue H, Chen J, Fan W
J Affect Disord 2024 Jul 1;356:48-53. Epub 2024 Apr 7 doi: 10.1016/j.jad.2024.04.006. PMID: 38593939
Stratified distribution of Th17 and Treg cells in patients with multi-stage rheumatoid arthritis.
Su R, Li B, Wu R, Xie Y, Gao A, Gao C, Li X, Wang C
Arthritis Res Ther 2023 Apr 4;25(1):55. doi: 10.1186/s13075-023-03041-7. PMID: 37016395Free PMC Article
Antigen-specific immunotherapies in type 1 diabetes.
Zhang X, Dong Y, Liu D, Yang L, Xu J, Wang Q
J Trace Elem Med Biol 2022 Sep;73:127040. Epub 2022 Jul 15 doi: 10.1016/j.jtemb.2022.127040. PMID: 35868165
Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease.
Koseva PM, Kamenov ZA, Nikolova MM, Andreeva-Gateva PA
Folia Med (Plovdiv) 2021 Aug 31;63(4):467-474. doi: 10.3897/folmed.63.e57193. PMID: 35851162
Autoimmune diseases in patients undergoing percutaneous coronary intervention: A risk factor for in-stent restenosis?
Pepe M, Napoli G, Carulli E, Moscarelli M, Forleo C, Nestola PL, Biondi-Zoccai G, Giordano A, Favale S
Atherosclerosis 2021 Sep;333:24-31. Epub 2021 Aug 5 doi: 10.1016/j.atherosclerosis.2021.08.007. PMID: 34418682

Diagnosis

Antigen-specific immunotherapies in type 1 diabetes.
Zhang X, Dong Y, Liu D, Yang L, Xu J, Wang Q
J Trace Elem Med Biol 2022 Sep;73:127040. Epub 2022 Jul 15 doi: 10.1016/j.jtemb.2022.127040. PMID: 35868165
Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease.
Koseva PM, Kamenov ZA, Nikolova MM, Andreeva-Gateva PA
Folia Med (Plovdiv) 2021 Aug 31;63(4):467-474. doi: 10.3897/folmed.63.e57193. PMID: 35851162
An inflammation classification system using cytokine parameters.
Roe K
Scand J Immunol 2021 Feb;93(2):e12970. Epub 2020 Sep 18 doi: 10.1111/sji.12970. PMID: 32892387
Chronic Nonbacterial Osteomyelitis and Chronic Recurrent Multifocal Osteomyelitis in Children.
Zhao Y, Ferguson PJ
Pediatr Clin North Am 2018 Aug;65(4):783-800. doi: 10.1016/j.pcl.2018.04.003. PMID: 30031498
Radiological manifestations of sarcoidosis.
Vagal AS, Shipley R, Meyer CA
Clin Dermatol 2007 May-Jun;25(3):312-25. doi: 10.1016/j.clindermatol.2007.03.009. PMID: 17560309

Therapy

Assessing the causal relationship between immune cell traits and depression by Mendelian randomization analysis.
Xue H, Chen J, Fan W
J Affect Disord 2024 Jul 1;356:48-53. Epub 2024 Apr 7 doi: 10.1016/j.jad.2024.04.006. PMID: 38593939
Autoimmune diseases in patients undergoing percutaneous coronary intervention: A risk factor for in-stent restenosis?
Pepe M, Napoli G, Carulli E, Moscarelli M, Forleo C, Nestola PL, Biondi-Zoccai G, Giordano A, Favale S
Atherosclerosis 2021 Sep;333:24-31. Epub 2021 Aug 5 doi: 10.1016/j.atherosclerosis.2021.08.007. PMID: 34418682
Chronic Nonbacterial Osteomyelitis and Chronic Recurrent Multifocal Osteomyelitis in Children.
Zhao Y, Ferguson PJ
Pediatr Clin North Am 2018 Aug;65(4):783-800. doi: 10.1016/j.pcl.2018.04.003. PMID: 30031498
Advances in mechanisms of systemic lupus erythematosus.
Dema B, Charles N
Discov Med 2014 May;17(95):247-55. PMID: 24882716
Vascular complications and gene therapy.
Roy S, Rothschild JG, Chen A
Expert Opin Biol Ther 2003 Feb;3(1):71-83. doi: 10.1517/14712598.3.1.71. PMID: 12718732

Prognosis

Unraveling the complex relationship: Multiple sclerosis, urinary tract infections, and infertility.
Seyedolmohadesin M, Ashkani M, Ghadikolaei TS, Mirshekar M, Bostanghadiri N, Aminzadeh S
Mult Scler Relat Disord 2024 Apr;84:105512. Epub 2024 Feb 20 doi: 10.1016/j.msard.2024.105512. PMID: 38428292
Stratified distribution of Th17 and Treg cells in patients with multi-stage rheumatoid arthritis.
Su R, Li B, Wu R, Xie Y, Gao A, Gao C, Li X, Wang C
Arthritis Res Ther 2023 Apr 4;25(1):55. doi: 10.1186/s13075-023-03041-7. PMID: 37016395Free PMC Article
Systemic immune responses after ischemic stroke: From the center to the periphery.
Wu F, Liu Z, Zhou L, Ye D, Zhu Y, Huang K, Weng Y, Xiong X, Zhan R, Shen J
Front Immunol 2022;13:911661. Epub 2022 Sep 20 doi: 10.3389/fimmu.2022.911661. PMID: 36211352Free PMC Article
Chronic Nonbacterial Osteomyelitis and Chronic Recurrent Multifocal Osteomyelitis in Children.
Zhao Y, Ferguson PJ
Pediatr Clin North Am 2018 Aug;65(4):783-800. doi: 10.1016/j.pcl.2018.04.003. PMID: 30031498
Primary open-angle glaucoma: neuroendocrine-immune disorder?
Zhang T, Xie X, Lu F
Med Hypotheses 2014 Oct;83(4):514-5. Epub 2014 Aug 20 doi: 10.1016/j.mehy.2014.08.017. PMID: 25175405

Clinical prediction guides

Assessing the causal relationship between immune cell traits and depression by Mendelian randomization analysis.
Xue H, Chen J, Fan W
J Affect Disord 2024 Jul 1;356:48-53. Epub 2024 Apr 7 doi: 10.1016/j.jad.2024.04.006. PMID: 38593939
Stratified distribution of Th17 and Treg cells in patients with multi-stage rheumatoid arthritis.
Su R, Li B, Wu R, Xie Y, Gao A, Gao C, Li X, Wang C
Arthritis Res Ther 2023 Apr 4;25(1):55. doi: 10.1186/s13075-023-03041-7. PMID: 37016395Free PMC Article
Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease.
Koseva PM, Kamenov ZA, Nikolova MM, Andreeva-Gateva PA
Folia Med (Plovdiv) 2021 Aug 31;63(4):467-474. doi: 10.3897/folmed.63.e57193. PMID: 35851162
Construction of an immune-related genes nomogram for the preoperative prediction of axillary lymph node metastasis in triple-negative breast cancer.
Tan W, Xie X, Huang Z, Chen L, Tang W, Zhu R, Ye X, Zhang X, Pan L, Gao J, Tang H, Zheng W
Artif Cells Nanomed Biotechnol 2020 Dec;48(1):288-297. doi: 10.1080/21691401.2019.1703731. PMID: 31858816
Primary open-angle glaucoma: neuroendocrine-immune disorder?
Zhang T, Xie X, Lu F
Med Hypotheses 2014 Oct;83(4):514-5. Epub 2014 Aug 20 doi: 10.1016/j.mehy.2014.08.017. PMID: 25175405

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